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AB181073

Anti-C6orf89 antibody [EPR13621]

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(4 Publications)

Rabbit Recombinant Monoclonal C6orf89 antibody. Suitable for WB and reacts with Human samples. Cited in 4 publications.

View Alternative Names

BRAP, UNQ177/PRO203, C6orf89, Bombesin receptor-activated protein C6orf89, Amfion

1 Images
Western blot - Anti-C6orf89 antibody [EPR13621] (AB181073)
  • WB

Supplier Data

Western blot - Anti-C6orf89 antibody [EPR13621] (AB181073)

All lanes:

Western blot - Anti-C6orf89 antibody [EPR13621] (ab181073) at 1/1000 dilution

Lane 1:

A549 cell lysate at 20 µg

Lane 2:

293 cell lysate at 20 µg

Lane 3:

HepG2 cell lysate at 20 µg

Secondary

All lanes:

Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution

Predicted band size: 40 kDa

false

  • Carrier free

    Anti-C6orf89 antibody [EPR13621] - BSA and Azide free

Key facts

Host species

Rabbit

Clonality

Monoclonal

Clone number

EPR13621

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

WB

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

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Primary Antibodies

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/2000", "WB-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Rat": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" } } }
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Product details

Patented technology
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

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Properties and storage information

Form
Liquid
Purity
Tissue culture supernatant
Storage buffer
Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

The C6orf89 protein also known as Chromosome 6 Open Reading Frame 89 has a molecular mass of about 18 kDa. Researchers have observed that this protein is widely expressed across various tissues. Its mechanical function is not fully characterized yet but studies suggest it might play a role in cellular processes due to its presence in multiple cell types.
Biological function summary

The role of C6orf89 remains largely ambiguous but researchers believe it may have links to cellular metabolism and regulatory processes. Currently there is no direct evidence suggesting that C6orf89 is part of a larger protein complex. More research is needed to uncover its specific biological functions and interactions with other molecular structures in the cell.

Pathways

Scientists have yet to allocate a precise pathway where C6orf89 functions prominently. It is essential to explore how it interacts with known cellular pathways such as the metabolic pathways or regulatory networks to understand its contribution better. Other proteins potentially like AMPK or mTOR signaling components might interact with it once its exact mechanistic role becomes clearer.

Researchers are investigating potential connections between C6orf89 and disorders like metabolic syndromes or certain cancers. No direct disease-related proteins have been conclusively linked to C6orf89 yet although alterations in its expression may subtly influence pathological conditions. Scientists are working on profiling its expression in disease contexts to establish direct associations and mechanisms.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Exhibits histone deacetylase (HDAC) enhancer properties (PubMed : 23460338). May play a role in cell cycle progression and wound repair of bronchial epithelial cells (PubMed : 21857995).
See full target information C6orf89
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Publications (4)

Recent publications for all applications. Explore the full list and refine your search

Clinical and experimental pharmacology & physiology 51:e13916 PubMed39155151

2024

Attenuation of renal fibrosis in mice due to lack of bombesin receptor-activated protein homologue.

Applications

Unspecified application

Species

Unspecified reactive species

Zhi Peng,Hui Wang,Jiaoyun Zheng,Hui Chen,Jie Wang,Horst Christian Weber,Lin Yuan,Xiaoqun Qin,Yang Xiang,Chi Liu,Ming Ji,Huijun Liu,Xiangping Qu

FEBS letters 597:2626-2642 PubMed37715941

2023

Knockout of the BRAP homolog in mice leads to abnormal tracheal cilia.

Applications

Unspecified application

Species

Unspecified reactive species

Hui Wang,Suhui Zuo,Jiaoyun Zheng,Zhi Peng,Xueping Yao,Jie Wang,Horst Christian Weber,Xiaoqun Qin,Yang Xiang,Chi Liu,Ming Ji,Huijun Liu,Lang Pan,Xiangping Qu

Life science alliance 5: PubMed35820707

2022

Lack of bombesin receptor-activated protein attenuates bleomycin-induced pulmonary fibrosis in mice.

Applications

Unspecified application

Species

Unspecified reactive species

Hui Wang,Wenrui Zhang,Rujiao Liu,Jiaoyun Zheng,Xueping Yao,Hui Chen,Jie Wang,Horst Christian Weber,Xiaoqun Qin,Yang Xiang,Chi Liu,Huijun Liu,Lang Pan,Xiangping Qu

JCI insight 5: PubMed32897879

2020

PPP2R2D suppresses IL-2 production and Treg function.

Applications

Unspecified application

Species

Unspecified reactive species

Wenliang Pan,Amir Sharabi,Andrew Ferretti,Yinfeng Zhang,Catalina Burbano,Nobuya Yoshida,Maria G Tsokos,George C Tsokos
View all publications
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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

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