JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB121743

Anti-C8orf55 antibody

Be the first to review this product! Submit a review

|

(2 Publications)

Rabbit Polyclonal C8orf55 antibody. Suitable for IHC-P, ICC, WB and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Recombinant Fragment Protein within Human THEM6 aa 100 to C-terminus.

View Alternative Names

C8orf55, PSEC0098, THEM6, Protein THEM6, Mesenchymal stem cell protein DSCD75, Thioesterase superfamily member 6

6 Images
Immunocytochemistry - Anti-C8orf55 antibody (AB121743)
  • ICC

Supplier Data

Immunocytochemistry - Anti-C8orf55 antibody (AB121743)

Immunofluorescent staining of Human cell line U-251MG shows positivity in nucleus but not nucleoli and cytoplasm. Recommended concentration of ab121743 is 0.04 μg/ml. Cells treated with PFA/Triton X-100.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-C8orf55 antibody (AB121743)
  • IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-C8orf55 antibody (AB121743)

ab121743, at a 1/1000 dilution staining C8orf55 in paraffin-embedded Human fallopian tube tissue by Immunohistochemistry.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-C8orf55 antibody (AB121743)
  • IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-C8orf55 antibody (AB121743)

ab121743, at a 1/1000 dilution staining C8orf55 in paraffin-embedded Human small intestine tissue by Immunohistochemistry.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-C8orf55 antibody (AB121743)
  • IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-C8orf55 antibody (AB121743)

ab121743, at a 1/1000 dilution staining C8orf55 in paraffin-embedded Human cerebellum tissue by Immunohistochemistry.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-C8orf55 antibody (AB121743)
  • IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-C8orf55 antibody (AB121743)

ab121743, at a 1/1000 dilution staining C8orf55 in paraffin-embedded Human kidney tissue by Immunohistochemistry.

Western blot - Anti-C8orf55 antibody (AB121743)
  • WB

Unknown

Western blot - Anti-C8orf55 antibody (AB121743)

All lanes:

Western blot - Anti-C8orf55 antibody (ab121743) at 0.04 µg/mL

Lane 1:

RT-4 lysate

Lane 2:

U-251 MG lysate

Lane 3:

Human plasma

Lane 4:

Human liver lysate

Lane 5:

Human tonsil lysate

Predicted band size: 24 kDa

true

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

WB, IHC-P, ICC

applications

Immunogen

Recombinant Fragment Protein within Human THEM6 aa 100 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.

Q8WUY1

style
left-column

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "ICC" : {"fullname" : "Immunocytochemistry", "shortname":"ICC"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/500 - 1/1000", "IHCP-species-notes": "<p></p> Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.", "ICC-species-checked": "testedAndGuaranteed", "ICC-species-dilution-info": "", "ICC-species-notes": "<p></p>", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "0.04-0.4 µg/mL", "WB-species-notes": "<p></p>" } } }
style
left-column
style
left-column

Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine)
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
style
left-column

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

C8orf55 is also known as Chromosome 8 Open Reading Frame 55. It is a protein with a molecular mass of approximately 23 kDa. Researchers have identified this protein in several tissues but it shows higher expression in the heart and skeletal muscles. The exact molecular mechanisms of C8orf55 remain under investigation but it appears to play a role in cellular processes such as metabolism or regulation of energy.
Biological function summary

Scientists see C8orf55 as integral in energy production and utilization within muscle tissues. While no established complex houses C8orf55 its functional significance suggests interactions with key metabolic proteins possibly occur. The protein's role hints at involvement in critical cellular efficiency processes and may impact muscle function and maintenance by influencing metabolic pathways.

Pathways

C8orf55 interacts significantly within cellular metabolic pathways particularly those involving mitochondrial function. It associates with the oxidative phosphorylation pathway an important energy-generation pathway. C8orf55 may relate to proteins such as ATP synthase through its involvement in producing cellular energy. Researchers speculate links with the electron transport chain connecting C8orf55 to essential bioenergetic processes.

C8orf55's role in metabolism indicates potential links to metabolic myopathies and heart-related conditions. The protein's involvement in energy pathways suggests that disruptions could associate with conditions like cardiomyopathy which affect heart muscles. Connections exist with proteins like creatine kinase hinting at broader implications for muscular energy diseases where C8orf55 could significantly impact the understanding or treatment of such disorders.
style
left-column
style
left-column

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
style
left-column

Target data

See full target information THEM6
style
left-column

Publications (2)

Recent publications for all applications. Explore the full list and refine your search

EMBO molecular medicine 14:e14764 PubMed35014179

2022

THEM6-mediated reprogramming of lipid metabolism supports treatment resistance in prostate cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Arnaud Blomme,Coralie Peter,Ernest Mui,Giovanny Rodriguez Blanco,Ning An,Louise M Mason,Lauren E Jamieson,Grace H McGregor,Sergio Lilla,Chara Ntala,Rachana Patel,Marc Thiry,Sonia H Y Kung,Marine Leclercq,Catriona A Ford,Linda K Rushworth,David J McGarry,Susan Mason,Peter Repiscak,Colin Nixon,Mark J Salji,Elke Markert,Gillian M MacKay,Jurre J Kamphorst,Duncan Graham,Karen Faulds,Ladan Fazli,Martin E Gleave,Edward Avezov,Joanne Edwards,Huabing Yin,David Sumpton,Karen Blyth,Pierre Close,Daniel J Murphy,Sara Zanivan,Hing Y Leung

Scientific reports 7:15585 PubMed29138412

2017

Novel KIAA0753 mutations extend the phenotype of skeletal ciliopathies.

Applications

Unspecified application

Species

Unspecified reactive species

A Hammarsjö,Z Wang,R Vaz,F Taylan,M Sedghi,K M Girisha,D Chitayat,K Neethukrishna,P Shannon,R Godoy,K Gowrishankar,A Lindstrand,J Nasiri,M Baktashian,P T Newton,L Guo,W Hofmeister,M Pettersson,A S Chagin,G Nishimura,L Yan,N Matsumoto,A Nordgren,N Miyake,G Grigelioniene,S Ikegawa
View all publications
style
left-column
style
left-column
style
right-column

Complementary Products

Primary Antibodies

AB166613

Anti-BBS1 antibody [EPR7906]

RabMAb|Recombinant

Immunocytochemistry/ Immunofluorescence - Anti-BBS1 antibody [EPR7906] (AB166613)

  • 0
  • 0
Primary Antibodies

AB8580

Anti-Histone H3 (tri methyl K4) antibody - ChIP Grade

BOND RX™ Validated

ChIP - Anti-Histone H3 (tri methyl K4) antibody - ChIP Grade (AB8580)

  • 5
  • 90
Primary Antibodies

AB26721

Anti-RNA polymerase II CTD repeat YSPTSPS antibody - ChIP Grade

BOND RX™ Validated

ChIP - Anti-RNA polymerase II CTD repeat YSPTSPS antibody - ChIP Grade (AB26721)

  • 4
  • 12
Primary Antibodies

AB16669

Anti-CD3 epsilon antibody [SP7]

BOND RX™ Validated|RabMAb|Advanced Validation|Recombinant|Lab Essentials|20ul selling size

Multiplex immunohistochemistry - Anti-CD3 epsilon antibody [SP7] (AB16669)

  • 4
  • 79

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com