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AB121701

Anti-C9orf169 antibody

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(1 Publication)

Rabbit Polyclonal C9orf169 antibody. Suitable for IHC-P, WB, ICC/IF and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human CYSRT1 aa 50 to C-terminus.

View Alternative Names

C9orf169, CYSRT1, Cysteine-rich tail protein 1

2 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-C9orf169 antibody (AB121701)
  • IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-C9orf169 antibody (AB121701)

ab121701, at a 1/225 dilution, staining C9orf169 in paraffin-embedded Human esophagus tissue by Immunohistochemistry.

Immunocytochemistry/ Immunofluorescence - Anti-C9orf169 antibody (AB121701)
  • ICC/IF

Unknown

Immunocytochemistry/ Immunofluorescence - Anti-C9orf169 antibody (AB121701)

Immunofluorescent staining of Human cell line U-2 OS shows positivity in nucleus but not nucleoli and vesicles. Recommended concentration of ab121701 1-4 µg/ml. Cells treated with PFA/Triton X-100.

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

ICC/IF, WB, IHC-P

applications

Immunogen

Recombinant Fragment Protein within Human CYSRT1 aa 50 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.

A8MQ03

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/200 - 1/500", "IHCP-species-notes": "<p></p> Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "0.04-0.4 µg/mL", "WB-species-notes": "<p></p>", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "0.25-2 µg/mL", "ICCIF-species-notes": "<p></p>" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine)
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

C9orf169 also known as Chromosome 9 open reading frame 169 is a protein that plays a role in cellular processes although its detailed mechanisms are not completely understood. It has a molecular mass of approximately 37 kDa. The protein is expressed in various tissues but data regarding which specific tissues show dominant expression remain limited. Researchers continue to explore the expression patterns to gain deeper insights into its functions.
Biological function summary

The C9orf169 protein contributes to regulatory functions within the cell. It is not yet identified as part of any known protein complex suggesting it might perform its roles either independently or as a transient component in cellular machinery. This lack of association with larger complexes makes it an important protein for study as understanding its isolated function could reveal novel mechanisms in cellular regulation.

Pathways

Researchers have identified that C9orf169 interacts with pathways involved in cell signaling and regulation. Its interactions may involve important cellular processes such as signal transduction and molecular transport. Although the protein does not appear as a central node in these pathways its interaction with proteins like those in the signal modulation field suggest it plays a supportive yet significant role in maintaining pathway efficiency.

C9orf169 has potential associations with certain neurological and autoimmune conditions though exact implications are still under investigation. Variants or expression changes of C9orf169 might relate to the dysregulation observed in these diseases as it indirectly influences proteins like those involved in immune modulation. Further studies are needed to understand fully how C9orf169 impacts these conditions at the molecular level.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Component of the stratum corneum that may contribute to epidermal antimicrobial host defenses.
See full target information CYSRT1
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Biomedicines 13: PubMed40427044

2025

The Expression and Molecular Roles of MAMDC2 in MSS Colorectal Cancer with a High Tumor Stromal Ratio.

Applications

Unspecified application

Species

Unspecified reactive species

Yiling Liu,Shengnan Qian,Jia Wei,Jianting He,Minghui Li,Xiaobing Gao,Hong Cai,Yiqing Wang,Yue Han,Tianyuan Tan,Minhui Yang
View all publications
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Product promise

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