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AB236115

Anti-C9orf64 antibody

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(1 Publication)

Rabbit Polyclonal C9orf64 antibody. Suitable for WB, IHC-P and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human QNG1 aa 150 to C-terminus.

View Alternative Names

C9orf64, QNG1, Queuosine 5'-phosphate N-glycosylase/hydrolase, Q-nucleotide N-glycosylase 1, Queuine salvage protein QNG1, Queuosine-nucleotide N-glycosylase/hydrolase

3 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-C9orf64 antibody (AB236115)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-C9orf64 antibody (AB236115)

Paraffin-embedded human liver cancer tissue stained for C9orf64 using ab236115 at 1/100 dilution in immunohistochemical analysis.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-C9orf64 antibody (AB236115)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-C9orf64 antibody (AB236115)

Paraffin-embedded human lung cancer tissue stained for C9orf64 using ab236115 at 1/100 dilution in immunohistochemical analysis.

Western blot - Anti-C9orf64 antibody (AB236115)
  • WB

Supplier Data

Western blot - Anti-C9orf64 antibody (AB236115)

All lanes:

Western blot - Anti-C9orf64 antibody (ab236115) at 1/1000 dilution

Lane 1:

HeLa (human epithelial cell line from cervix adenocarcinoma) whole cell lysate

Lane 2:

K562 (human chronic myelogenous leukemia cell line from bone marrow) whole cell lysate

Lane 3:

HepG2 (human liver hepatocellular carcinoma cell line) whole cell lysate

Secondary

All lanes:

Goat polyclonal to Rabbit IgG at 1/10000 dilution

Predicted band size: 39 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

IHC-P, WB

applications

Immunogen

Recombinant Fragment Protein within Human QNG1 aa 150 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.

Q5T6V5

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/5000", "WB-species-notes": "<p></p>", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/20 - 1/200", "IHCP-species-notes": "<p></p>" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein G
Purification notes
Purity >95%.
Storage buffer
pH: 7.4 Preservative: 0.03% Proclin 300 Constituents: PBS, 50% Glycerol (glycerin, glycerine)
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

C9orf64 also known as Chromosome 9 Open Reading Frame 64 is a protein encoded by the C9orf64 gene. The protein has a molecular mass of approximately 27 kDa. It is widely expressed in various human tissues including the brain and immune system cells. Its mechanical function involves interactions at the cellular level potentially influencing cellular processes through its localization in the cytoplasm and association with cell membranes.
Biological function summary

C9orf64 plays a role in certain immune and neurological functions. This protein does not yet have a well-established biological complex but research suggests it may be involved in cellular signaling. C9orf64 is suggested to interact with key cellular proteins indicating a part in modulating cellular responses and maintaining cellular homeostasis.

Pathways

C9orf64 is involved in immune response pathways and possibly signal transduction processes. It may participate in the innate immune signaling pathway interacting with proteins such as NF-kB which regulates gene expression related to immune responses. C9orf64's role in these pathways indicates its potential influence in regulating immune system activities and modulation.

C9orf64 appears associated with autoimmune conditions and neurological disorders. Its involvement in these diseases might link to its interaction with proteins impacting immune cell function like MHC class II molecules. Further research may reveal more on C9orf64's specific contributions to pathologies and regulatory mechanisms in these and potentially other diseases.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Catalyzes the hydrolysis of queuosine 5'-phosphate, releasing the nucleobase queuine (q). Is required for salvage of queuine from exogenous queuosine (Q) that is imported and then converted to queuosine 5'-phosphate intracellularly. In vitro, can also catalyze the release of the q base directly from Q as substrate; however, it was shown that Q is not the biologically relevant substrate. Shows a very low activity on queuosine 3',5'-diphosphate, and cannot release q from queuosine 3'-phosphate and from the 5'-nucleotides AMP, UMP, CMP or GMP, indicating specificity for the queuine base (PubMed : 36610787). Can complement the yeast mutant SPAC589.05c, restoring Q incorporation into tRNA (PubMed : 24911101).
See full target information QNG1
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Annals of translational medicine 10:1383 PubMed36660674

2023

G0S2 ameliorates oxidized low-density lipoprotein-induced vascular endothelial cell injury by regulating mitochondrial apoptosis.

Applications

Unspecified application

Species

Unspecified reactive species

Zenghui Liang,Wenjie Diao,Yiyao Jiang,Yanrong Zhang
View all publications
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Product promise

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