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Rabbit Polyclonal CALML5 antibody. Suitable for IHC-P, WB and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human Calmodulin-like protein 5 aa 1 to C-terminus.

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Images

Western blot - Anti-CALML5 antibody (AB154631), expandable thumbnail
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CALML5 antibody (AB154631), expandable thumbnail

Publications

Key facts

Isotype

IgG

Host species

Rabbit

Storage buffer

pH: 7
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 20% Glycerol (glycerin, glycerine), 1.21% Tris, 0.75% Glycine

Form

Liquid

Clonality

Polyclonal

Immunogen

  • Recombinant Fragment Protein within Human Calmodulin-like protein 5 aa 1 to C-terminus. The exact immunogen used to generate this antibody is proprietary information. Database link Q9NZT1

Reactivity data

Select an application
Product promiseTestedExpectedPredictedNot recommended
IHC-PWB
Human
Tested
Tested

Tested
Tested

Species

Human

Dilution info

1/100.00000 - 1/1000.00000

Notes

Alternatively Tris-EDTA buffer (pH8.0) may be used.

Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Tested
Tested

Species

Human

Dilution info

1/500.00000 - 1/3000.00000

Notes

-

Associated Products

Select an associated product type

1 product for Alternative Product

Target data

Function

Binds calcium. May be involved in terminal differentiation of keratinocytes.

Alternative names

Recommended products

Rabbit Polyclonal CALML5 antibody. Suitable for IHC-P, WB and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human Calmodulin-like protein 5 aa 1 to C-terminus.

Key facts

Isotype

IgG

Form

Liquid

Clonality

Polyclonal

Immunogen
  • Recombinant Fragment Protein within Human Calmodulin-like protein 5 aa 1 to C-terminus. The exact immunogen used to generate this antibody is proprietary information. Database link Q9NZT1
Purification technique

Affinity purification Immunogen

Concentration
Loading...

Storage

Shipped at conditions

Blue Ice

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

Notes

Abcam is leading the way to address reproducibility in scientific research with our highly validated recombinant monoclonal and recombinant multiclonal antibodies. Search & select one of Abcam's thousands of recombinant alternatives to eliminate batch-variability and unnecessary animal use.

If you do not find a host species to meet your needs, our catalogue and custom Chimeric range provides scientists the specificity of Abcam's RabMAbs in the species backbone of your choice. Remember to also review our range of edited cell lines, proteins and biochemicals relevant to your target that may help you further your research goals.

Abcam antibodies are extensively validated in a wide range of species and applications, so please check the reagent specifications meet your scientific needs before purchasing. If you have any questions or bespoke requirements, simply visit the Contact Us page to send us an inquiry or contact our Support Team ahead of purchase.

Supplementary info

This supplementary information is collated from multiple sources and compiled automatically.

Activity summary

CALML5 also known as calmodulin-like protein 5 is a small calcium-binding protein with a molecular weight of approximately 15 kDa. It shares structural similarities with calmodulin but has a distinct expression pattern. This protein is strongly expressed in keratinocytes particularly in the epidermis and is involved in the calcium-mediated signaling processes that regulate skin cell function and differentiation.

Biological function summary

CALML5 modulates processes involved in epidermal homeostasis and repair. It plays an important role in the regulation of keratinocyte differentiation an essential process for proper skin barrier function. CALML5 does not form part of a large molecular complex but interacts with other calcium-binding proteins to influence epidermal physiology.

Pathways

CALML5 is integrated into the calcium signaling pathway which is critical for calcium-dependent regulation of keratinocyte activity. It relates closely to other proteins within this pathway such as calcium-binding proteins like calmodulin. Its activity is important in relaying calcium signals that influence cellular processes like cell proliferation and differentiation.

Associated diseases and disorders

CALML5 has links to skin conditions such as psoriasis and certain types of dermatitis where epidermal differentiation is disrupted. CALML5 may interact with proteins such as keratin to influence these disease processes highlighting its potential role in the maintenance of epidermal health and integrity. Understanding its functions could lead to new therapeutic strategies for managing skin-related disorders.

Product promise

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In the unlikely event of one of our products not working as expected, you are covered by our product promise.

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2 product images

  • Western blot - Anti-CALML5 antibody (ab154631), expandable thumbnail

    Western blot - Anti-CALML5 antibody (ab154631)

    15% SDS PAGE

    All lanes: Western blot - Anti-CALML5 antibody (ab154631) at 1/1000 dilution

    All lanes: A431 whole cell lysate at 30 µg

    Predicted band size: 16 kDa

  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CALML5 antibody (ab154631), expandable thumbnail

    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CALML5 antibody (ab154631)

    Immunohistochemical analysis of paraffin-embedded Human hepatoma tissue, labeling CALML5 with ab154631 at 1/500 dilution.

Downloads

Product protocols

For this product, it's our understanding that no specific protocols are required. You can:

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