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AB18847

Anti-Calreticulin antibody

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(2 Publications)

Rabbit Polyclonal Calreticulin antibody. Suitable for WB and reacts with Human samples. Cited in 2 publications.

View Alternative Names

CRTC, CALR, Calreticulin, CRP55, Calregulin, Endoplasmic reticulum resident protein 60, HACBP, grp60, ERp60

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

WB

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

Specificity

Recognizes a 60 kDa calreticulin on SDS-PAGE immunoblots. Jurkat cell lysate can be used as a positive control.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "guaranteed", "WB-species-dilution-info": "", "WB-species-notes": "<p></p>" } } }
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Product details

This product is manufactured by BioVision, an Abcam company and was previously called 3077 Calreticulin Antibody. 3077-100 is the same size as the 100 µg size of ab18847
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Properties and storage information

Form
Liquid
Storage buffer
pH: 7.2 Preservative: 0.01% Thimerosal (merthiolate) Constituents: 69% PBS, 30% Glycerol (glycerin, glycerine), 0.5% BSA
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER (PubMed : 7876246). Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export (PubMed : 11149926). Involved in maternal gene expression regulation. May participate in oocyte maturation via the regulation of calcium homeostasis (By similarity). Present in the cortical granules of non-activated oocytes, is exocytosed during the cortical reaction in response to oocyte activation and might participate in the block to polyspermy (By similarity).
See full target information CALR
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Publications (2)

Recent publications for all applications. Explore the full list and refine your search

Brain sciences 11: PubMed34827513

2021

The Role of Neutrophil Extracellular Traps in Lipopolysaccharide-Induced Depression-like Behaviors in Mice.

Applications

Unspecified application

Species

Unspecified reactive species

Yue Kong,Guiqin He,Xiaolin Zhang,Jin Li

Annals of biomedical engineering 43:2361-73 PubMed25777294

2015

Liver-Tumor Hybrid Organoids for Modeling Tumor Growth and Drug Response In Vitro.

Applications

Unspecified application

Species

Unspecified reactive species

Aleksander Skardal,Mahesh Devarasetty,Christopher Rodman,Anthony Atala,Shay Soker
View all publications
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Product promise

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