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AB227713

Anti-CAMTA1 antibody

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(3 Publications)

Rabbit Polyclonal CAMTA1 antibody. Suitable for WB and reacts with Human samples. Cited in 3 publications. Immunogen corresponding to Recombinant Fragment Protein within Human CAMTA1.

View Alternative Names

KIAA0833, MSTP023, CAMTA1, Calmodulin-binding transcription activator 1

1 Images
Western blot - Anti-CAMTA1 antibody (AB227713)
  • WB

Supplier Data

Western blot - Anti-CAMTA1 antibody (AB227713)

5% SDS-PAGE

All lanes:

Western blot - Anti-CAMTA1 antibody (ab227713) at 1/1000 dilution

Lane 1:

Non-transfected HEK-293T (human epithelial cell line from embryonic kidney transformed with large T antigen) whole cell extract at 30 µg

Lane 2:

hCAMTA1-transfected HEK-293T (human epithelial cell line from embryonic kidney transformed with large T antigen) whole cell extract at 30 µg

Predicted band size: 183 kDa

true

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

WB

applications

Immunogen

Recombinant Fragment Protein within Human CAMTA1. The exact immunogen used to generate this antibody is proprietary information.

Q9Y6Y1

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/3000", "WB-species-notes": "<p></p>" }, "Rat": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7 Preservative: 0.025% Proclin 300 Constituents: PBS, 20% Glycerol (glycerin, glycerine)
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

CAMTA1 also known as calmodulin-binding transcription activator 1 is a transcription factor with a mass of approximately 130 kDa. CAMTA1 plays an important role in gene regulation through its DNA-binding domain. This protein is highly expressed in the brain heart and skeletal muscle indicating its importance in these tissues. CAMTA1 contains a CG-1 DNA-binding domain ankyrin repeats and a calmodulin-binding IQ motif which help in its interaction with different cellular components.
Biological function summary

CAMTA1 regulates the expression of genes involved in the response to environmental stress and the development of neuronal and cardiac tissues. As part of a transcriptional regulatory complex CAMTA1 can recruit other co-factors to modulate gene expression. It influences processes such as neuronal differentiation and cardiac hypertrophy. Its expression pattern and transcriptional activity suggest that it helps maintain cellular homeostasis under varying physiological conditions.

Pathways

CAMTA1 has significant roles in two central biological pathways: calcium signaling and stress response pathways. These pathways are important for neuronal and cardiac function. In calcium signaling CAMTA1 acts alongside other proteins like calmodulin to modulate the expression of genes critical for calcium homeostasis. In stress response pathways it helps regulate genes that protect against cellular stress often collaborating with transcription factors such as MEF2C to mediate stress responses.

CAMTA1 is associated with neurodevelopmental disorders and cardiac diseases. Mutations or dysregulation of CAMTA1 expression might contribute to conditions such as ataxia and congenital heart defects. Studies have linked CAMTA1 with other proteins including MEF2C in the context of cardiac development issues suggesting a complex network of interactions essential for normal physiological function.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Transcriptional activator.
See full target information CAMTA1
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Publications (3)

Recent publications for all applications. Explore the full list and refine your search

Frontiers in veterinary science 10:1102049 PubMed36846267

2023

Extracellular vesicles would be involved in the release and delivery of seminal TGF-β isoforms in pigs.

Applications

Unspecified application

Species

Unspecified reactive species

Lorena Padilla,Isabel Barranco,Jesús Martínez-Hernández,Ana Parra,Inmaculada Parrilla,Luis Miguel Pastor,Heriberto Rodriguez-Martinez,Xiomara Lucas,Jordi Roca

Oxidative medicine and cellular longevity 2023:3308725 PubMed36785792

2023

MBNL1-AS1 Promotes Hypoxia-Induced Myocardial Infarction via the miR-132-3p/RAB14/CAMTA1 Axis.

Applications

Unspecified application

Species

Unspecified reactive species

Yanbing Li,Min Zong,Xiaonan Guan,Xuejiao Wu,Guiling Ma,Yu Wei,Zhi Li

Translational oncology 15:101282 PubMed34800915

2021

LncRNA RBPMS-AS1 promotes NRGN transcription to enhance the radiosensitivity of glioblastoma through the microRNA-301a-3p/CAMTA1 axis.

Applications

Unspecified application

Species

Unspecified reactive species

Wenyang Li,Yan Cui,Wenjia Ma,Ming Wang,Yang Cai,Yugang Jiang
View all publications
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