AB244360

Anti-Caprin-1 antibody

Name: Anti-Caprin-1 antibody (ab244360) | Abcam
Brand: Abcam Limited
SKU: AB244360
Price: 630 USD
Availability: InStock

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(3 Publications)

Rabbit Polyclonal Caprin-1 antibody. Suitable for IHC-P, WB, ICC/IF and reacts with Human samples. Cited in 3 publications. Immunogen corresponding to Recombinant Fragment Protein within Human CAPRIN1 aa 200-350.

View Alternative Names

GPIAP1, GPIP137, M11S1, RNG105, CAPRIN1, Caprin-1, Cell cycle-associated protein 1, Cytoplasmic activation- and proliferation-associated protein 1, GPI-anchored membrane protein 1, GPI-anchored protein p137, Membrane component chromosome 11 surface marker 1, RNA granule protein 105, GPI-p137, p137GPI

6 Images

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Caprin-1 antibody (AB244360)

IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Caprin-1 antibody (AB244360)

Formalin-fixed, paraffin-embedded human cerebral cortex tissue stained for Caprin-1 with ab244360 at a 1/500 dilution in immunohistochemical analysis.

IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Caprin-1 antibody (AB244360)

Formalin-fixed, paraffin-embedded human testis tissue stained for Caprin-1 with ab244360 at a 1/500 dilution in immunohistochemical analysis.

Immunocytochemistry/ Immunofluorescence - Anti-Caprin-1 antibody (AB244360)

ICC/IF

Unknown

Immunocytochemistry/ Immunofluorescence - Anti-Caprin-1 antibody (AB244360)

PFA fixed, Triton X-100 permeabilized U-2 OS (Human bone osteosarcoma epithelial cell line) cells labeling Caprin-1 using ab244360 at 4 μg/ml (green) in ICC/IF.

IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Caprin-1 antibody (AB244360)

Formalin-fixed, paraffin-embedded human skeletal muscle tissue stained for Caprin-1 with ab244360 at a 1/500 dilution in immunohistochemical analysis.

IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Caprin-1 antibody (AB244360)

Formalin-fixed, paraffin-embedded human fallopian tube tissue stained for Caprin-1 with ab244360 at a 1/500 dilution in immunohistochemical analysis.

Unknown

Western blot - Anti-Caprin-1 antibody (AB244360)

All lanes:

Western blot - Anti-Caprin-1 antibody (ab244360) at 0.4 µg/mL

Lane 1:

RH-30 cell line

Lane 2:

NB4 cell line

Predicted band size: 78 kDa

Observed band size: 116 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

Reacts with

Human

Applications

IHC-P, WB, ICC/IF

applications

Immunogen

Recombinant Fragment Protein within Human CAPRIN1 aa 200-350. The exact immunogen used to generate this antibody is proprietary information.

Q14444

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/500 - 1/1000", "IHCP-species-notes": " Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "0.04-0.4 µg/mL", "WB-species-notes": "", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "0.25-2 µg/mL", "ICCIF-species-notes": "Fixation/Permeabilization: PFA/Triton X-100." }, "Mouse": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Rat": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Cow": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" } } }

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Immunogen

Storage buffer

pH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine)

Shipped at conditions

Blue Ice

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

mRNA-binding protein that acts as a regulator of mRNAs transport, translation and/or stability, and which is involved in neurogenesis, synaptic plasticity in neurons and cell proliferation and migration in multiple cell types (PubMed : 17210633, PubMed : 31439799, PubMed : 35979925). Plays an essential role in cytoplasmic stress granule formation (PubMed : 35977029). Acts as an mRNA regulator by mediating formation of some phase-separated membraneless compartment : undergoes liquid-liquid phase separation upon binding to target mRNAs, leading to assemble mRNAs into cytoplasmic ribonucleoprotein granules that concentrate mRNAs with associated regulatory factors (PubMed : 31439799, PubMed : 32302570, PubMed : 32302571, PubMed : 32302572, PubMed : 34074792, PubMed : 36040869, PubMed : 36279435). Undergoes liquid-liquid phase separation following phosphorylation and interaction with FMR1, promoting formation of cytoplasmic ribonucleoprotein granules that concentrate mRNAs with factors that inhibit translation and mediate deadenylation of target mRNAs (PubMed : 31439799). In these cytoplasmic ribonucleoprotein granules, CAPRIN1 mediates recruitment of CNOT7 deadenylase, leading to mRNA deadenylation and degradation (PubMed : 31439799). Binds directly and selectively to MYC and CCND2 mRNAs (PubMed : 17210633). In neuronal cells, directly binds to several mRNAs associated with RNA granules, including BDNF, CAMK2A, CREB1, MAP2, NTRK2 mRNAs, as well as to GRIN1 and KPNB1 mRNAs, but not to rRNAs (PubMed : 17210633).

See full target information CAPRIN1

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Publications (3)

Recent publications for all applications. Explore the full list and refine your search

Molecular medicine (Cambridge, Mass.) 31:278 PubMed40819077

2025

Targeting LINC02544/miR-497-5p/CAPRIN1 axis via exosome-based siRNA to overcome immunotherapy resistance in triple-negative breast cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Bin Lian,Jiayi Li,Shihui Tang,Ting Li,Jinping Li

Biomolecules 12: PubMed36291750

2022

Type I Interferon Receptor Subunit 1 Deletion Attenuates Experimental Abdominal Aortic Aneurysm Formation.

Applications

Unspecified application

Species

Unspecified reactive species

Takahiro Shoji,Jia Guo,Yingbin Ge,Yankui Li,Gang Li,Toru Ikezoe,Wei Wang,Xiaoya Zheng,Sihai Zhao,Naoki Fujimura,Jianhua Huang,Baohui Xu,Ronald L Dalman

3 Biotech 10:453 PubMed33088650

2020

MicroRNA-199a-5p suppresses the cell growth of colorectal cancer by targeting oncogene Caprin1.

Applications

Unspecified application

Species

Unspecified reactive species

Xiangyang Yu,Yanfang He,Yan Wang,Yajuan Tang,Yanjuan Guo,Jinling Yuan,Jinghe Bai,Tao Yao,Xiongzhi Wu

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-Caprin-1 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Caprin-1 antibody (AB244360)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Caprin-1 antibody (AB244360)

Immunocytochemistry/ Immunofluorescence - Anti-Caprin-1 antibody (AB244360)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Caprin-1 antibody (AB244360)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Caprin-1 antibody (AB244360)

Western blot - Anti-Caprin-1 antibody (AB244360)

Key facts

Host species

Clonality

Isotype

Carrier free

Reacts with

Applications

Immunogen

Reactivity data

Properties and storage information

Form

Purification technique

Storage buffer

Shipped at conditions

Appropriate short-term storage duration

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Aliquoting information

Storage information

Product protocols

Target data

Publications (3)

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