AB27684

Anti-Carboxymethyl Lysine antibody

Name: Anti-Carboxymethyl Lysine antibody (ab27684) | Abcam
Brand: Abcam Limited
SKU: AB27684
Price: 500 USD
Availability: InStock
Rating: 4 (3 reviews)

(3 Reviews)

(49 Publications)

Rabbit Polyclonal Carboxymethyl Lysine antibody. Suitable for ELISA, WB and reacts with Modified Amino Acid samples. Cited in 49 publications.

View Alternative Names

CML, N Epsilon (Carboxymethyl) Lysine

1 Images

AbReview26544****

Western blot - Anti-Carboxymethyl Lysine antibody (AB27684)

Blocking Step : 2% Milk for 30 minutes at 25°C

All lanes:

Western blot - Anti-Carboxymethyl Lysine antibody (ab27684) at 1/1000 dilution

Lane 1:

Whole tissue lysate of raw cashew nuts at 50 µg

Lane 2:

Whole tissue lysate of roasted cashew nuts at 50 µg

Secondary

All lanes:

An HRP-conjugated Goat anti-rabbit polyclonal

Observed band size: 12-Oct kDa

true

Exposure time: 1min

This image is courtesy of an Abreview submitted by Chris Mattison

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

Applications

ELISA, WB

applications

Specificity

This antibody specifically binds to Carboxy methyl Lysine modified proteins.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "ELISA" : {"fullname" : "ELISA", "shortname":"ELISA"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Modified Amino Acid": { "ELISA-species-checked": "guaranteed", "ELISA-species-dilution-info": "", "ELISA-species-notes": "<p></p>", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "", "WB-species-notes": "<p></p>" } } }

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Properties and storage information

Form

Liquid

Purification notes

This antibody was purified by Carboxy methyl Lysine protein Sepharose affinity column.

Storage buffer

pH: 7.2 - 7.4 Preservative: 0.02% Sodium azide Constituents: PBS, 30% Glycerol (glycerin, glycerine), 1.23% Sodium phosphate, 0.44% Sodium chloride, 0.015% EDTA

Shipped at conditions

Blue Ice

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

+4°C

Aliquoting information

Upon delivery aliquot

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

See full target information Carboxymethyl Lysine

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Publications (49)

Recent publications for all applications. Explore the full list and refine your search

Dermatopathology (Basel, Switzerland) 12: PubMed40558676

2025

Influence of Aging and Diabetes on the Mechanical Properties of Mouse Skin.

Applications

Unspecified application

Species

Unspecified reactive species

Sarah Miny,Gaël Runel,Julien Chlasta,Christelle Bonod

International journal of molecular sciences 24: PubMed37958795

2023

Nε-Carboxymethyl-Lysine Modification of Extracellular Matrix Proteins Augments Fibroblast Activation.

Applications

Unspecified application

Species

Unspecified reactive species

Harshavardhana H Ediga,Patrick Hester,Adithi Yepuri,Geereddy Bhanuprakash Reddy,Satish K Madala

Scientific reports 13:12948 PubMed37558746

2023

Alpha cell receptor for advanced glycation end products associate with glucagon expression in type 1 diabetes.

Applications

Unspecified application

Species

Unspecified reactive species

Sherman S Leung,Nataliya Lenchik,Clayton Mathews,Alberto Pugliese,Domenica A McCarthy,Selena Le Bagge,Adam Ewing,Mark Harris,Kristen J Radford,Danielle J Borg,Ivan Gerling,Josephine M Forbes

Journal of molecular medicine (Berlin, Germany) 101:1015-1028 PubMed37462767

2023

Novel insights into the nervous system affected by prolonged hyperglycemia.

Applications

Unspecified application

Species

Unspecified reactive species

Kamila Zglejc-Waszak,Konark Mukherjee,Agnieszka Korytko,Bogdan Lewczuk,Andrzej Pomianowski,Joanna Wojtkiewicz,Marta Banach,Michał Załęcki,Natalia Nowicka,Julia Jarosławska,Bernard Kordas,Krzysztof Wąsowicz,Judyta K Juranek

Molecular medicine reports 27: PubMed36999595

2023

Hesperetin treatment attenuates glycation of lens proteins and advanced‑glycation end products generation.

Applications

Unspecified application

Species

Unspecified reactive species

Yuri Doki,Yosuke Nakazawa,Naoki Morishita,Shin Endo,Noriaki Nagai,Naoki Yamamoto,Hiroomi Tamura,Megumi Funakoshi-Tago

Proceedings of the National Academy of Sciences of the United States of America 120:e2219054120 PubMed36574676

2022

Bioprosthetic heart valve structural degeneration associated with metabolic syndrome: Mitigation with polyoxazoline modification.

Applications

Unspecified application

Species

Unspecified reactive species

Alexey Abramov,Yingfei Xue,Andrey Zakharchenko,Mangesh Kurade,Rajesh K Soni,Robert J Levy,Giovanni Ferrari

Antioxidants (Basel, Switzerland) 11: PubMed36290746

2022

Aerobic Exercise Training Reduces Atherogenesis Induced by Low-Sodium Diet in LDL Receptor Knockout Mice.

Applications

Unspecified application

Species

Unspecified reactive species

Ana Paula Garcia Bochi,Guilherme da Silva Ferreira,Vanessa Del Bianco,Paula Ramos Pinto,Letícia Gomes Rodrigues,Mayara da Silva Trevisani,Luzia Naoko Shinohara Furukawa,Kely Cristina Soares Bispo,Alexandre Alves da Silva,Ana Paula Pereira Velosa,Edna Regina Nakandakare,Ubiratan Fabres Machado,Walcy Paganelli Rosolia Teodoro,Marisa Passarelli,Sergio Catanozi

Neuropathology : official journal of the Japanese Society of Neuropathology 43:84-94 PubMed35915909

2022

The receptor for advanced glycation end products and its ligands' expression in OVE26 diabetic sciatic nerve during the development of length-dependent neuropathy.

Applications

Unspecified application

Species

Unspecified reactive species

Kamila Zglejc-Waszak,Ann Marie Schmidt,Judyta K Juranek

Basic research in cardiology 117:36 PubMed35834066

2022

Renal denervation reduces atrial remodeling in hypertensive rats with metabolic syndrome.

Applications

Unspecified application

Species

Unspecified reactive species

Simina-Ramona Selejan,Dominik Linz,Muriel Mauz,Mathias Hohl,Anh Khoa Dennis Huynh,Thimoteus Speer,Jan Wintrich,Andrey Kazakov,Christian Werner,Felix Mahfoud,Michael Böhm

Scientific reports 12:2688 PubMed35177666

2022

Glycation damage to organelles and their DNA increases during maize seedling development.

Applications

Unspecified application

Species

Unspecified reactive species

Diwaker Tripathi,Delene J Oldenburg,Arnold J Bendich

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-Carboxymethyl Lysine antibody

Western blot - Anti-Carboxymethyl Lysine antibody (AB27684)

Key facts

Host species

Clonality

Isotype

Carrier free

Applications

Specificity

Reactivity data

Properties and storage information

Form

Purification notes

Storage buffer

Shipped at conditions

Appropriate short-term storage duration

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Aliquoting information

Product protocols

Target data

Publications (49)

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