Rabbit Recombinant Monoclonal Carboxypeptidase B2 antibody. Suitable for WB and reacts with Human samples.
Images
![Western blot - Anti-Carboxypeptidase B2 antibody [EPR7858] (AB133679), expandable thumbnail](https://content.abcam.com/products/images/carboxypeptidase-b2-antibody-epr7858-ab133679--western-blot-img124364.jpg/_jcr_content/renditions/webp-475.webp "Western blot - Anti-Carboxypeptidase B2 antibody [EPR7858] (AB133679)")
![OI-RD Scanning - Anti-Carboxypeptidase B2 antibody [EPR7858] (AB133679), expandable thumbnail](https://content.abcam.com/products/images/carboxypeptidase-b2-antibody-epr7858-ab133679--oi-rd-scanning-img98488.jpg/_jcr_content/renditions/webp-475.webp "OI-RD Scanning - Anti-Carboxypeptidase B2 antibody [EPR7858] (AB133679)")
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7.2 - 7.4
Preservative: 0.01% Sodium azide
Constituents: 50% Tissue culture supernatant, 40% Glycerol (glycerin, glycerine), 9% PBS, 0.05% BSA- Form
- Liquid
- Clonality
- Monoclonal
Immunogen
- The exact immunogen used to generate this antibody is proprietary information.
Reactivity data
Select an application| IP | WB | IHC-P | |
|---|---|---|---|
| Human | Not recommended | Tested | Not recommended |
| Mouse | Not recommended | Predicted | Not recommended |
| Rat | Not recommended | Predicted | Not recommended |
IP
Not recommendedNot recommended
| Species | Dilution info | Notes |
|---|---|---|
Species Human, Mouse, Rat | Dilution info - | Notes - |
WB
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info 1/1000 - 1/10000 | Notes - |
PredictedPredicted
| Species | Dilution info | Notes |
|---|---|---|
Species Mouse, Rat | Dilution info - | Notes - |
IHC-P
Not recommendedNot recommended
| Species | Dilution info | Notes |
|---|---|---|
Species Human, Mouse, Rat | Dilution info - | Notes - |
Target data
Function
Cleaves C-terminal arginine or lysine residues from biologically active peptides such as kinins or anaphylatoxins in the circulation thereby regulating their activities. Down-regulates fibrinolysis by removing C-terminal lysine residues from fibrin that has already been partially degraded by plasmin.
Alternative names
Carboxypeptidase B2, Carboxypeptidase U, Plasma carboxypeptidase B, Thrombin-activable fibrinolysis inhibitor, CPU, pCPB, TAFI, CPB2
Recommended products
Rabbit Recombinant Monoclonal Carboxypeptidase B2 antibody. Suitable for WB and reacts with Human samples.
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7.2 - 7.4
Preservative: 0.01% Sodium azide
Constituents: 50% Tissue culture supernatant, 40% Glycerol (glycerin, glycerine), 9% PBS, 0.05% BSA- Form
- Liquid
- Clonality
- Monoclonal
- Immunogen
- The exact immunogen used to generate this antibody is proprietary information.
- Clone number
- EPR7858
- Purity
- Tissue culture supernatant
- Dissociation constant
- 3.67 x 10-11 M
- Concentration
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage conditions
- +4°C
- Appropriate long-term storage conditions
- -20°C
- Aliquoting information
- Upon delivery aliquot
- Storage information
- Avoid freeze / thaw cycle
Notes
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free batch production
For more information, read more on recombinant antibodies.
Product promise
Tested
We have tested this species and application combination and it works. It is covered by our product promise.
Expected
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
Predicted
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
Not recommended
We do not recommend this combination. It is not covered by our product promise.
We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.
In the unlikely event of one of our products not working as expected, you are covered by our product promise.
Full details and terms and conditions can be found here:
Terms & Conditions.
2 product images
![Western blot - Anti-Carboxypeptidase B2 antibody [EPR7858] (ab133679), expandable thumbnail](https://content.abcam.com/products/images/carboxypeptidase-b2-antibody-epr7858-ab133679--western-blot-img124364.jpg "Western blot - Anti-Carboxypeptidase B2 antibody [EPR7858] (ab133679)")
Western blot - Anti-Carboxypeptidase B2 antibody [EPR7858] (ab133679)
All lanes: Western blot - Anti-Carboxypeptidase B2 antibody [EPR7858] (ab133679) at 1/1000 dilution
Lane 1: Human platelet lysate at 10 µg
Lane 2: Human plasma lysate at 10 µg
SecondaryAll lanes: Goat anti-rabbit HRP conjugated antibody at 1/2000 dilution
Predicted band size: 48 kDa
![OI-RD Scanning - Anti-Carboxypeptidase B2 antibody [EPR7858] (ab133679), expandable thumbnail](https://content.abcam.com/products/images/carboxypeptidase-b2-antibody-epr7858-ab133679--oi-rd-scanning-img98488.jpg "OI-RD Scanning - Anti-Carboxypeptidase B2 antibody [EPR7858] (ab133679)")
OI-RD Scanning - Anti-Carboxypeptidase B2 antibody [EPR7858] (ab133679)
We have systematically measured KD (the equilibrium dissociation constant between the antibody and its antigen), of more than 840 recombinant antibodies to assess not only their individual KD values but also to see the average affinity of antibody.
Based on the comparison with published literature values for mouse monoclonal antibodies, Recombinant antibodies appear to be on average 1-2 order of magnitude higher affinity.
Downloads
Product protocols
- Visit the general protocols
- Visit troubleshooting
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