AB59420

Anti-cardiac Troponin I (phospho S43) antibody

Name: Anti-cardiac Troponin I (phospho S43) antibody (ab59420) | Abcam
Brand: Abcam Limited
SKU: AB59420
Price: 535 USD
Availability: InStock
Rating: 2 (2 reviews)

(2 Reviews)

(2 Publications)

Rabbit Polyclonal Cardiac Troponin I phospho S43 antibody. Suitable for WB and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Synthetic Peptide within Human TNNI3 phospho S43 aa 1-100.

View Alternative Names

TNNC1, TNNI3, Cardiac troponin I

1 Images

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Western blot - Anti-cardiac Troponin I (phospho S43) antibody (AB59420)

All lanes:

Western blot - Anti-cardiac Troponin I (phospho S43) antibody (ab59420) at 1/500 dilution

Lane 1:

Jurkat cells

Lane 2:

Jurkat cells with blocking phosphopeptide

Predicted band size: 24 kDa

Observed band size: 30 kDa

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Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

Reacts with

Human

Applications

applications

Immunogen

Synthetic Peptide within Human TNNI3 phospho S43 aa 1-100. The exact immunogen used to generate this antibody is proprietary information.

P19429

Specificity

Detects endogenous levels of Troponin I only when phosphorylated at serine 43

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/1000", "WB-species-notes": "<p></p>" } } }

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Immunogen

Purification notes

The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site

Storage buffer

pH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine), 0.87% Sodium chloride

Shipped at conditions

Blue Ice

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Storage information

Stable for 12 months at -20°C

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.

See full target information TNNI3 phospho S43

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Publications (2)

Recent publications for all applications. Explore the full list and refine your search

PloS one 9:e99024 PubMed24919197

2014

RhoA/ROCK signaling and pleiotropic α1A-adrenergic receptor regulation of cardiac contractility.

Applications

Species

Mouse

Ze-Yan Yu,Ju-Chiat Tan,Aisling C McMahon,Siiri E Iismaa,Xiao-Hui Xiao,Scott H Kesteven,Melissa E Reichelt,Marion C Mohl,Nicola J Smith,Diane Fatkin,David Allen,Stewart I Head,Robert M Graham,Michael P Feneley

Brazilian journal of medical and biological resear 46:128-37 PubMed23369981

2013

TNNI3K is a novel mediator of myofilament function and phosphorylates cardiac troponin I.

Applications

Unspecified application

Species

Unspecified reactive species

Hui Wang,Lin Wang,Li Song,Yan-Wan Zhang,Jue Ye,Rui-Xia Xu,Na Shi,Xian-Min Meng

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-cardiac Troponin I (phospho S43) antibody

Western blot - Anti-cardiac Troponin I (phospho S43) antibody (AB59420)

Key facts

Host species

Clonality

Isotype

Carrier free

Reacts with

Applications

Immunogen

Specificity

Reactivity data

Properties and storage information

Form

Purification technique

Purification notes

Storage buffer

Shipped at conditions

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Storage information

Product protocols

Target data

Publications (2)

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