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AB137383

Anti-Carma 3 antibody

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(5 Publications)

Rabbit Polyclonal Carma 3 antibody. Suitable for WB and reacts with Human, Mouse samples. Cited in 5 publications. Immunogen corresponding to Recombinant Fragment Protein within Human CARD10 aa 300-650.

View Alternative Names

CARMA3, CARD10, Caspase recruitment domain-containing protein 10, CARD-containing MAGUK protein 3, Carma 3

3 Images
Western blot - Anti-Carma 3 antibody (AB137383)
  • WB

Supplier Data

Western blot - Anti-Carma 3 antibody (AB137383)

Samples were separated by 5 % SDS. Corresponding RNA expression data for the same cell lines are based on Human Protein Atlas program.

All lanes:

Western blot - Anti-Carma 3 antibody (ab137383) at 1/1000 dilution

Lane 1:

Non-transfected 293T whole cell extract at 30 µg

Lanes 2 - 3:

Carma 3 shRNA transfected 293T whole cell extract at 30 µg

Secondary

All lanes:

HRP-conjugated anti-rabbit IgG antibody

Predicted band size: 116 kDa

false

Western blot - Anti-Carma 3 antibody (AB137383)
  • WB

Supplier Data

Western blot - Anti-Carma 3 antibody (AB137383)

Samples were separated by 7.5 % SDS. Corresponding RNA expression data for the same cell lines are based on Human Protein Atlas program.

All lanes:

Western blot - Anti-Carma 3 antibody (ab137383) at 1/1000 dilution

Lane 1:

A431 whole cell lysate at 30 µg

Lane 2:

HeLa whole cell lysate at 30 µg

Lane 3:

HepG2 whole cell lysate at 30 µg

Secondary

All lanes:

HRP-conjugated anti-rabbit IgG antibody

Predicted band size: 116 kDa

false

Western blot - Anti-Carma 3 antibody (AB137383)
  • WB

Supplier Data

Western blot - Anti-Carma 3 antibody (AB137383)

Samples were separated by 5 % SDS. The signal was developed with Trident ECL plus-Enhanced.

All lanes:

Western blot - Anti-Carma 3 antibody (ab137383) at 1/500 dilution

All lanes:

Mouse heart tissue extract at 50 µg

Secondary

All lanes:

HRP-conjugated anti-rabbit IgG antibody

Predicted band size: 116 kDa

true

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human, Mouse

Applications

WB

applications

Immunogen

Recombinant Fragment Protein within Human CARD10 aa 300-650. The exact immunogen used to generate this antibody is proprietary information.

Q9BWT7

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/3000", "WB-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/3000", "WB-species-notes": "<p></p>" }, "Rat": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7 Preservative: 0.01% Thimerosal (merthiolate) Constituents: 10% Glycerol (glycerin, glycerine), 1.21% Tris, 0.75% Glycine
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Scaffold protein that plays an important role in mediating the activation of NF-kappa-B via BCL10 or EGFR.
See full target information CARD10
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Publications (5)

Recent publications for all applications. Explore the full list and refine your search

Cancers 13: PubMed34885061

2021

CARMA3 Promotes Colorectal Cancer Cell Motility and Cancer Stemness via YAP-Mediated NF-κB Activation.

Applications

Unspecified application

Species

Unspecified reactive species

Ting-Yu Chang,Cheng-Tien Wu,Meei-Ling Sheu,Rong-Sen Yang,Shing-Hwa Liu

Technology in cancer research & treatment 20:15330338211027915 PubMed34190011

2021

CARMA3 Transcriptional Regulation of STMN1 by NF-κB Promotes Renal Cell Carcinoma Proliferation and Invasion.

Applications

Unspecified application

Species

Unspecified reactive species

Du Shi,Zhe Zhang,Chuize Kong

Oncogenesis 10:32 PubMed33824280

2021

CARD10 cleavage by MALT1 restricts lung carcinoma growth in vivo.

Applications

Unspecified application

Species

Unspecified reactive species

Laura Israël,Anton Glück,Marjorie Berger,Marine Coral,Melanie Ceci,Adeline Unterreiner,Joëlle Rubert,Maureen Bardet,Stefanie Ginster,Alexandra M Golding-Ochsenbein,Kea Martin,Thomas Hoyler,Thomas Calzascia,Grazyna Wieczorek,Rainer Hillenbrand,Stéphane Ferretti,Enrico Ferrero,Frédéric Bornancin

Nature cell biology 21:1604-1614 PubMed31792381

2019

TBKBP1 and TBK1 form a growth factor signalling axis mediating immunosuppression and tumourigenesis.

Applications

Unspecified application

Species

Unspecified reactive species

Lele Zhu,Yanchuan Li,Xiaoping Xie,Xiaofei Zhou,Meidi Gu,Zuliang Jie,Chun-Jung Ko,Tianxiao Gao,Blanca E Hernandez,Xuhong Cheng,Shao-Cong Sun

FASEB journal : official publication of the Federa 30:3216-26 PubMed27297585

2016

MicroRNA-181b inhibits thrombin-mediated endothelial activation and arterial thrombosis by targeting caspase recruitment domain family member 10.

Applications

Unspecified application

Species

Unspecified reactive species

Jibin Lin,Shaolin He,Xinghui Sun,Gregory Franck,Yihuan Deng,Dafeng Yang,Stefan Haemmig,A K M Wara,Basak Icli,Dazhu Li,Mark W Feinberg
View all publications
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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

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