JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB183864

Anti-CC137 antibody

Be the first to review this product! Submit a review

|

(2 Publications)

Rabbit Polyclonal CC137 antibody. Suitable for WB and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Recombinant Fragment Protein within Human CCDC137 aa 1 to C-terminus.

View Alternative Names

cPERP-B, CCDC137, Coiled-coil domain-containing protein 137

1 Images
Western blot - Anti-CC137 antibody (AB183864)
  • WB

Supplier Data

Western blot - Anti-CC137 antibody (AB183864)

All lanes:

Western blot - Anti-CC137 antibody (ab183864) at 1/1000 dilution

Lane 1:

A549 whole cell lysate/extract at 30 µg

Lane 2:

H1299 whole cell lysate/extract at 30 µg

Lane 3:

HCT116 whole cell lysate/extract at 30 µg

Predicted band size: 33 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

WB

applications

Immunogen

Recombinant Fragment Protein within Human CCDC137 aa 1 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.

Q6PK04

style
left-column

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/3000", "WB-species-notes": "<p></p>" } } }
style
left-column
style
left-column

Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7 Preservative: 0.01% Thimerosal (merthiolate) Constituents: 20% Glycerol (glycerin, glycerine), 1.21% Tris, 0.75% Glycine
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
style
left-column

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

The CC137 protein also known as C-C motif chemokine ligand 13 (CCL13) functions mechanically as a cytokine involved in immune system signaling. This protein has a molecular mass of approximately 10 kDa. It is mainly expressed in immune cells including macrophages monocytes and lymphocytes. The CC137 protein can induce chemotaxis directing the movement of immune cells to sites of inflammation and infection.
Biological function summary

CC137 is essential for modulating immune responses and is part of the chemokine family which regulates the migration of leukocytes. CC137 can form part of a larger cytokine signaling complex enhancing the communication between immune cells. It is involved in the regulation of inflammatory responses by activating specific receptors on the surface of target cells which leads to the activation of intracellular signaling pathways.

Pathways

CC137 participates in the chemokine signaling pathway and the JAK-STAT signaling pathway. It plays a role in the recruitment and activation of immune cells through interactions with chemokine receptors like CCR2 and CCR3. These pathways are important for movements and activation of various immune cell types linking CC137 to proteins such as JAK2 and STAT3 which are integral to signal transduction processes.

CC137 has been implicated in inflammatory diseases and allergic responses. It is connected to asthma through its role in promoting eosinophil movement and activation. Additionally CC137 is linked to rheumatoid arthritis where aberrant expression contributes to chronic inflammation within joints. In these diseases CC137 can interact with TNF-alpha a critical cytokine related to inflammation and immune responses.
style
left-column
style
left-column

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
style
left-column

Target data

See full target information CCDC137
style
left-column

Publications (2)

Recent publications for all applications. Explore the full list and refine your search

Molecular therapy : the journal of the American Society of Gene Therapy 30:75-91 PubMed34371182

2021

Comprehensive transcriptome-wide analysis of spliceopathy correction of myotonic dystrophy using CRISPR-Cas9 in iPSCs-derived cardiomyocytes.

Applications

Unspecified application

Species

Unspecified reactive species

Sumitava Dastidar,Debanjana Majumdar,Jaitip Tipanee,Kshitiz Singh,Arnaud F Klein,Denis Furling,Marinee K Chuah,Thierry VandenDriessche

eLife 9: PubMed32538781

2020

HIV-1 Vpr induces cell cycle arrest and enhances viral gene expression by depleting CCDC137.

Applications

Unspecified application

Species

Unspecified reactive species

Fengwen Zhang,Paul D Bieniasz
View all publications
style
left-column
style
left-column
style
right-column

Alternative Products

Primary Antibodies

AB185368

Anti-CC137 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CC137 antibody (AB185368)

  • 0
  • 0

Complementary Products

Primary Antibodies

AB239501

Anti-Galectin 2 antibody [C6]

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Galectin 2 antibody [C6] (AB239501)

  • 0
  • 0
Primary Antibodies

AB108421

Anti-DcR2 antibody [EPR3588(2)]

BOND RX™ Validated|RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-DcR2 antibody [EPR3588(2)] (AB108421)

  • 0
  • 0
Primary Antibodies

AB223477

Anti-ZKSCAN3 antibody

Immunocytochemistry/ Immunofluorescence - Anti-ZKSCAN3 antibody (AB223477)

  • 0
  • 0
Primary Antibodies

AB166917

Anti-Cullin 2/CUL-2 antibody [EPR3104(2)]

RabMAb|Recombinant

Flow Cytometry (Intracellular) - Anti-Cullin 2/CUL-2 antibody [EPR3104(2)] (AB166917)

  • 5
  • 3

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com