Anti-CCL21 antibody
4
(4 Reviews)
|
(8 Publications)
Rabbit Polyclonal CCL21 antibody. Suitable for ELISA, WB, sELISA, IHC-P and reacts with Human samples. Cited in 8 publications. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human CCL21.
View Alternative Names
SCYA21, UNQ784/PRO1600, CCL21, C-C motif chemokine 21, 6Ckine, Beta-chemokine exodus-2, Secondary lymphoid-tissue chemokine, Small-inducible cytokine A21, SLC
- sELISA
Supplier Data
Sandwich ELISA - Anti-CCL21 antibody (AB9851)
Sandwich ELISA : To detect Human Exodus-2 (CCL21) by sandwich ELISA (using 100 µL/well antibody solution) a concentration of 0.5-2.0 µg/mL of CCL21 Polyclonal Antibody (ab9851) is required. This antigen affinity purified antibody, in conjunction with PeproTech CCL21 Polyclonal Antibody, Biotin (ab83130) as a detection antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant Human Exodus-2 (CCL21).
Reactivity data
Product details
Properties and storage information
Form
Reconstitution
Purification technique
Shipped at conditions
Appropriate short-term storage duration
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Aliquoting information
Supplementary information
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
CCL21 is essential for guiding immune cells to areas where they are needed for initiating immune responses. It forms a non-covalent complex with its receptor CCR7 a primary mechanism through which it exerts its biological effects. CCL21 coordinates the positioning of immune cells within the lymphoid organs ensuring a functional and effective immune response to pathogens or injuries. Its expression pattern aids in the organization of lymphoid tissue architecture and contributes to efficient trafficking of T-cells and dendritic cells.
Pathways
CCL21 plays an important role in the chemokine signaling pathway and the leukocyte transendothelial migration pathway. Within these pathways CCL21 works closely with its receptor CCR7 to guide immune cell navigation and localization. This collaboration is essential for directing cells to appropriate sites in the immune system aligning CCL21 with similar proteins like CCL19 another chemokine that also interacts with CCR7.
Product protocols
- Visit the General protocols
- Visit the Troubleshooting
Target data
Publications (8)
Recent publications for all applications. Explore the full list and refine your search
Gastroenterology 159:665-681.e13 PubMed32330476
2020
Applications
Unspecified application
Species
Unspecified reactive species
Cell death & disease 10:935 PubMed31819043
2019
Applications
Unspecified application
Species
Unspecified reactive species
The journal of histochemistry and cytochemistry : 67:299-308 PubMed30633620
2019
Applications
Unspecified application
Species
Unspecified reactive species
Bio-protocol 8: PubMed29780855
2018
Applications
Unspecified application
Species
Unspecified reactive species
eLife 6: PubMed28971799
2017
Applications
Unspecified application
Species
Unspecified reactive species
Oncotarget 8:25650-25659 PubMed27783999
2016
Applications
IHC
Species
Human
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 10:520-38 PubMed23775067
2013
Applications
IHC, WB
Species
Unspecified reactive species, Unspecified reactive species
The American journal of pathology 178:1662-75 PubMed21435450
2011
Applications
Unspecified application
Species
Unspecified reactive species
Product promise
Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.
For licensing inquiries, please contact partnerships@abcam.com