Mouse Monoclonal CD101 antibody. Suitable for Flow Cyt and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Cell preparation containing CD101 protein.
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CD101, EWI101, IGSF2, V7, Immunoglobulin superfamily member 2, IgSF2, Cell surface glycoprotein V7, Glu-Trp-Ile EWI motif-containing protein 101, EWI-101
- Flow Cyt
Supplier Data
Flow Cytometry - Anti-CD101 antibody [BB27] (AB192342)
Separation of human CD101 positive CD16 negative lymphocytes (red-filled) CD101 negative CD16 negative lymphocytes (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood using ab192342 (concentration in sample 0.56 μg/ml, GAM FITC).
- Flow Cyt
Supplier Data
Flow Cytometry - Anti-CD101 antibody [BB27] (AB192342)
Flow cytometry surface staining pattern of human peripheral whole blood stained using ab192342 (concentration in sample 0.56 μg/ml, GAM FITC).
- Flow Cyt
Supplier Data
Flow Cytometry - Anti-CD101 antibody [BB27] (AB192342)
Flow cytometry multicolor surface staining of human lymphocytes stained using ab192342 (concentration in sample 0.56 μg/ml, GAM FITC) and anti-human CD16 (3G8) APC antibody (10 μl reagent / 100 μl of peripheral whole blood).
Related conjugates and formulations (1)
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578 PE
PE Anti-CD101 antibody [BB27]
Reactivity data
Properties and storage information
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Shipped at conditions
Appropriate short-term storage duration
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Supplementary information
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
CD101 influences the immune response through its regulatory effects on cell signaling and interaction. The protein's function often centers within a complex environment contributing to the inhibitory signaling pathways that help balance immune activation. Its presence on regulatory T cells suggests a role in suppressing overactive immune responses which is important to maintaining immune homeostasis. Researchers associate CD101 expression with the control of inflammatory processes highlighting its functional significance.
Pathways
Research shows that CD101 participates in pathways key to immune regulation such as the T-cell receptor signaling pathway. This involvement connects CD101 with proteins like CD3 and CD4 emphasizing its role in modulating T-cell response. The protein plays a part in downstream signaling events that fine-tune immune responses by dampening excessive activation therefore helping prevent autoimmune reactions. It ensures the immune system effectively targets pathogens without harming host tissues.
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Target data
Publications (1)
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Journal of biomedical science 23:90 PubMed27931227
2016
Applications
Unspecified application
Species
Unspecified reactive species
Product promise
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