Anti-CD105 antibody [3A9]
3
(1 Review)
|
(20 Publications)
Mouse Monoclonal CD105 antibody. Suitable for Flow Cyt, ELISA, WB, IHC-P, ICC/IF and reacts with Human, Synthetic peptide samples. Cited in 20 publications. Immunogen corresponding to Recombinant Fragment Protein within Human ENG.
View Alternative Names
CD105, END, ENG, Endoglin
- Flow Cyt
Unknown
Flow Cytometry - Anti-CD105 antibody [3A9] (AB114052)
Flow cytometric analysis of CD105 in HepG2 cells, using ab114052 at a 1/200 dilution (green) and negative control (purple).
- ICC/IF
Unknown
Immunocytochemistry/ Immunofluorescence - Anti-CD105 antibody [3A9] (AB114052)
ab114052, at a 1/200 dilution, staining CD105 in HepG2 cells by Immunofluorescence (green).
Blue : DRAQ5 fluorescent DNA dye.
Red : Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
- IHC-P
Unknown
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD105 antibody [3A9] (AB114052)
ab114052, at a 1/200 dilution, staining CD105 in paraffin embedded Human kidney cancer tissue by Immunohistochemistry, with DAB staining.
- IHC-P
Unknown
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD105 antibody [3A9] (AB114052)
ab114052, at a 1/200 dilution, staining CD105 in paraffin embedded Human stomach cancer tissue by Immunohistochemistry, with DAB staining.
- ELISA
Unknown
ELISA - Anti-CD105 antibody [3A9] (AB114052)
ELISA using ab114052.
- WB
Unknown
Western blot - Anti-CD105 antibody [3A9] (AB114052)
All lanes:
Western blot - Anti-CD105 antibody [3A9] (ab114052) at 1/500 dilution
Lane 1:
HEK293 cell lysate
Lane 2:
CD105-hIgGFc transfected HEK293 cell lysate
Predicted band size: 70 kDa
false
Reactivity data
Product details
Properties and storage information
Form
Purification technique
Purification notes
Storage buffer
Shipped at conditions
Appropriate short-term storage duration
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Supplementary information
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
Endoglin functions in the regulation of angiogenesis and vascular remodeling. It plays a significant role in mediating cellular responses to TGF-beta signaling influencing endothelial cell proliferation and migration. While not part of a larger structural complex endoglin interacts with receptors and signaling molecules important for vascular development and repair processes. This involvement aids in maintaining endothelial integrity and function under various physiological conditions.
Pathways
CD105 participates in the TGF-beta signaling and angiogenesis pathways. In these pathways it acts in conjunction with other proteins like TGF-beta receptors which play roles in cell differentiation proliferation and apoptosis. The interaction between CD105 and TGF-beta signaling regulates numerous cellular mechanisms impacting angiogenesis and cellular responses to environmental changes.
Product protocols
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Target data
Publications (20)
Recent publications for all applications. Explore the full list and refine your search
Renal failure 47:2537797 PubMed40775738
2025
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Journal of nanobiotechnology 22:493 PubMed39160590
2024
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Neural regeneration research 19:900-907 PubMed37843227
2023
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Bioactive materials 25:256-272 PubMed36825224
2023
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Cancers 14: PubMed36358805
2022
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Cell journal 24:458-464 PubMed36093805
2022
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Frontiers in bioengineering and biotechnology 9:761861 PubMed34660561
2021
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Nature communications 11:3062 PubMed32546788
2020
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Angiogenesis 23:231-247 PubMed31897911
2020
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Scientific reports 9:19150 PubMed31844158
2019
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Product promise
Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.
For licensing inquiries, please contact partnerships@abcam.com