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AB227300

Anti-CD163L1 antibody - N-terminal

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(1 Publication)

Rabbit Polyclonal CD163L1 antibody. N-terminal. Suitable for WB and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human CD163L1.

View Alternative Names

CD163b, CD163B, M160, UNQ6434/PRO23202, CD163L1, Scavenger receptor cysteine-rich type 1 protein M160, CD163 antigen-like 1

1 Images
Western blot - Anti-CD163L1 antibody - N-terminal (AB227300)
  • WB

Supplier Data

Western blot - Anti-CD163L1 antibody - N-terminal (AB227300)

5% SDS-PAGE

All lanes:

Western blot - Anti-CD163L1 antibody - N-terminal (ab227300) at 1/1000 dilution

Lane 1:

Raji (human Burkitt's lymphoma cell line) whole cell extracts at 30 µg

Lane 2:

NCI-H929 (human bone marrow lymphoblast cell line) whole cell extracts at 30 µg

Predicted band size: 159 kDa

true

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

WB

applications

Immunogen

Recombinant Fragment Protein within Human CD163L1. The exact immunogen used to generate this antibody is proprietary information.

Q9NR16

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/3000", "WB-species-notes": "<p></p>" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7 Preservative: 0.025% Proclin 300 Constituents: PBS, 20% Glycerol (glycerin, glycerine)
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

CD163L1 also known as CD163-like 1 or M160 is a protein that acts as a scavenger receptor. This protein mechanically functions by binding to specific ligands and mediates endocytosis. CD163L1 belongs to the scavenger receptor cysteine-rich (SRCR) family which is involved in the clearance of hemoglobin-haptoglobin complexes. It is a type I membrane protein with an approximate mass of 150 kDa. The expression of CD163L1 is mainly detected in monocytes macrophages and certain dendritic cells usually in tissues associated with the immune response.
Biological function summary

This protein influences immune system processes related to inflammation. CD163L1 is part of the innate immune system and may be involved in the response to bacterial infections. It participates in the recognition and removal of apoptotic cells and pathogens. Though not a part of a protein complex its function aligns with receptors that mediate anti-inflammatory responses and tissue homeostasis in the body.

Pathways

This scavenger receptor associates with the anti-inflammatory pathway particularly in modulating responses to inflammation. It operates within a network involving the clearance and recycling of hemoglobin-heme. CD163L1 is linked with other proteins like CD163 which share similar clearing functions and SRCR domains are evident in their structure confirming their roles in host defense mechanisms.

CD163L1 shows relevance in conditions related to inflammation and immune dysfunction. For instance the receptor's activity is noted in the context of atherosclerosis as it can contribute to plaque stability due to its role in clearing hemoglobin-derived oxidants. It also connects to autoimmune diseases through its involvement with the dampening of inflammatory responses. In these conditions CD163L1 coordinates with proteins such as CD163 and other scavenger receptors that modulate immune responses.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

See full target information CD163L1
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Diabetes, metabolic syndrome and obesity : targets and therapy 18:217-231 PubMed39896707

2025

PEDF Overexpression Ameliorates Cardiac Lipotoxicity in Diabetic Cardiomyopathy via Regulation of Energy Metabolism.

Applications

Unspecified application

Species

Unspecified reactive species

Tuohua Mao,Ye Wang
View all publications
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