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AB96064

Anti-CD172 gamma antibody

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(1 Publication)

Rabbit Polyclonal CD172 gamma antibody. Suitable for WB and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human SIRPG aa 1-350.

View Alternative Names

CD172g, SIRPB2, SIRPG, Signal-regulatory protein gamma, SIRP-gamma, CD172 antigen-like family member B, Signal-regulatory protein beta-2, SIRP-b2, SIRP-beta-2

1 Images
Western blot - Anti-CD172 gamma antibody (AB96064)
  • WB

Unknown

Western blot - Anti-CD172 gamma antibody (AB96064)

12% SDS PAGE

All lanes:

Western blot - Anti-CD172 gamma antibody (ab96064) at 1/500 dilution

All lanes:

HepG2 whole cell lysate at 30 µg

Predicted band size: 42 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

WB

applications

Immunogen

Recombinant Fragment Protein within Human SIRPG aa 1-350. The exact immunogen used to generate this antibody is proprietary information.

Q9P1W8

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/3000", "WB-species-notes": "<p></p>" } } }

Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7 Preservative: 0.01% Thimerosal (merthiolate) Constituents: 10% Glycerol (glycerin, glycerine), 1.21% Tris, 0.75% Glycine
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

CD172 gamma also known as SIRP gamma or signal-regulatory protein gamma is part of the signal-regulatory protein family. This protein has a molecular mass of approximately 44 kDa. CD172 gamma is a transmembrane protein expressed mainly on the surface of immune cells including T lymphocytes and to a lesser extent on other specific blood cells. It acts through its extracellular Ig-like domains which enable it to participate in cell-cell interactions.
Biological function summary

CD172 gamma plays a role in immune response modulation. It functions as a part of a receptor complex that assists in cell signaling and communication. This involvement includes facilitating interactions between immune cells and presenting antigens which can impact cell activation and response. CD172 gamma has specific interactions that contribute to the regulation of the immune system further enhancing its role in defining cellular activity.

Pathways

CD172 gamma engages in immune signaling pathways. This protein is notably associated with the antigen presentation pathway where it plays a significant role in adaptive immune response. It works in conjunction with other proteins like SIRP alpha and SIRP beta forming a network that modulates immune cell signaling and activity. It influences the pathway interactions that determine how immune cells respond to various stimuli.

CD172 gamma has connections to immune-related conditions. In particular this protein has been studied in the context of autoimmune diseases where its role in immune signaling can affect disease progression. It is also linked to certain hematological disorders influencing the behavior of blood cells. CD172 gamma interacts with proteins like CD47 in these disease processes playing a distinct role in the modulation and potential progression of these conditions.

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Target data

Probable immunoglobulin-like cell surface receptor. On binding with CD47, mediates cell-cell adhesion. Engagement on T-cells by CD47 on antigen-presenting cells results in enhanced antigen-specific T-cell proliferation and costimulates T-cell activation.
See full target information SIRPG

Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Frontiers in cell and developmental biology 11:1111684 PubMed37261075

2023

Recapitulating porcine cardiac development : from expanded potential stem cell to embryo culture models.

Applications

Unspecified application

Species

Unspecified reactive species

Hilansi Rawat,Jessica Kornherr,Dorota Zawada,Sara Bakhshiyeva,Christian Kupatt,Karl-Ludwig Laugwitz,Andrea Bähr,Tatjana Dorn,Alessandra Moretti,Monika Nowak-Imialek
View all publications

Product promise

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