Anti-CD1a antibody [C1A/711]
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(8 Publications)
Mouse Monoclonal CD1A antibody. Suitable for IHC-P, IP, Flow Cyt, WB, ICC/IF, IHC-Fr and reacts with Human samples. Cited in 8 publications. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human CD1A.
View Alternative Names
CD1a, T-cell surface glycoprotein CD1a, T-cell surface antigen T6/Leu-6, hTa1 thymocyte antigen, CD1A
- IHC-P
Supplier Data
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD1a antibody [C1A/711] (AB201337)
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human skin tissue labeling CD1a with ab201337 at 1 μg/ml.
Reactivity data
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Supplementary information
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Biological function summary
CD1a participates in the immune system by presenting lipid and glycolipid antigens to T lymphocytes including natural killer T (NKT) cells. It forms a complex with β2-microglobulin which is essential for its proper function and antigen presentation. CD1a expression helps differentiate between types of dendritic cells with CD1a-positive cells often engaging in specific responses to microbial lipid antigens.
Pathways
CD1a plays a significant role in the antigen presentation pathway particularly in lipid antigen presentation to T cells. This is important for initiating immune responses. It interacts with related proteins such as CD1b and CD1c which also present lipid antigens. CD1a has implications in innate and adaptive immunity and can influence pathways involved in microbial recognition and elimination.
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Target data
Publications (8)
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Scientific reports 15:30313 PubMed40830367
2025
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Bioengineering & translational medicine 10:e10738 PubMed40060763
2025
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Parasite immunology 45:e12971 PubMed36695719
2023
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Scientific data 6:323 PubMed31848351
2019
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Free radical biology & medicine 139:80-91 PubMed31078730
2019
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Photodiagnosis and photodynamic therapy 26:270-276 PubMed30986538
2019
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International journal of cancer 144:117-124 PubMed30098202
2018
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The British journal of dermatology 177:809-817 PubMed28132413
2017
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