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AB205017

Anti-CD2AP antibody

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(2 Publications)

Rabbit Polyclonal CD2AP antibody. Suitable for IP, WB and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Recombinant Fragment Protein within Human CD2-associated protein.

View Alternative Names

CD2-associated protein, Adapter protein CMS, Cas ligand with multiple SH3 domains, CD2AP

2 Images
Immunoprecipitation - Anti-CD2AP antibody (AB205017)
  • IP

Supplier Data

Immunoprecipitation - Anti-CD2AP antibody (AB205017)

Detection of CD2AP in Immunoprecipitates of 293T whole cell lysates (1 mg for IP, 20% of IP loaded) using ab205017 at 6 μg/mg lysate for IP (Lane 1). For WB detection an ab205017 was used at 0.4 μg/ml. Lane 2 represents control IgG IP. Detection : Chemiluminescence with an exposure time of 30 seconds.

All lanes:

Immunoprecipitation - Anti-CD2AP antibody (ab205017)

Predicted band size: 71 kDa

false

Western blot - Anti-CD2AP antibody (AB205017)
  • WB

Supplier Data

Western blot - Anti-CD2AP antibody (AB205017)

All lanes:

Western blot - Anti-CD2AP antibody (ab205017) at 0.1 µg/mL

Lane 1:

HeLa whole cell lysate at 50 µg

Lane 2:

293T whole cell lysate at 50 µg

Lane 3:

Jurkat whole cell lysate at 50 µg

Predicted band size: 71 kDa

true

Exposure time: 30s

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

WB, IP

applications

Immunogen

Recombinant Fragment Protein within Human CD2-associated protein. The exact immunogen used to generate this antibody is proprietary information.

Q9Y5K6

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IP" : {"fullname" : "Immunoprecipitation", "shortname":"IP"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IP-species-checked": "testedAndGuaranteed", "IP-species-dilution-info": "2-10 µg/mg of lysate", "IP-species-notes": "<p></p>", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/2000 - 1/10000", "WB-species-notes": "<p></p>" } } }

Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7 - 8 Preservative: 0.09% Sodium azide Constituents: 99% Tris citrate/phosphate
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Target data

Seems to act as an adapter protein between membrane proteins and the actin cytoskeleton (PubMed : 10339567). In collaboration with CBLC, modulates the rate of RET turnover and may act as regulatory checkpoint that limits the potency of GDNF on neuronal survival. Controls CBLC function, converting it from an inhibitor to a promoter of RET degradation (By similarity). May play a role in receptor clustering and cytoskeletal polarity in the junction between T-cell and antigen-presenting cell (By similarity). May anchor the podocyte slit diaphragm to the actin cytoskeleton in renal glomerolus. Also required for cytokinesis (PubMed : 15800069). Plays a role in epithelial cell junctions formation (PubMed : 22891260).
See full target information CD2-associated protein

Publications (2)

Recent publications for all applications. Explore the full list and refine your search

Theranostics 15:3234-3256 PubMed40093906

2025

CRISPR screening reveals ZNF217 as a vulnerability in high-risk B-cell acute lymphoblastic leukemia.

Applications

Unspecified application

Species

Unspecified reactive species

Xi Qin,Keren Zhou,Lei Dong,Lu Yang,Wei Li,Zhenhua Chen,Chao Shen,Li Han,Yangchan Li,Anthony K N Chan,Sheela Pangeni Pokharel,Ying Qing,Meiling Chen,Kitty Wang,Keith Leung,Lillian Sau,Chun-Wei Chen,Xiaolan Deng,Rui Su,Jianjun Chen

Scientific reports 10:6787 PubMed32321993

2020

A proximity-labeling proteomic approach to investigate invadopodia molecular landscape in breast cancer cells.

Applications

Unspecified application

Species

Unspecified reactive species

Sylvie Thuault,Claire Mamelonet,Joëlle Salameh,Kevin Ostacolo,Brice Chanez,Danièle Salaün,Emilie Baudelet,Stéphane Audebert,Luc Camoin,Ali Badache
View all publications

Product promise

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