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AB46922

Anti-CD31 antibody [B-B38] - BSA and Azide free

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(1 Publication)

Mouse Monoclonal CD31 antibody. Carrier free. Suitable for Flow Cyt and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human PECAM1.

View Alternative Names

CD31, Platelet endothelial cell adhesion molecule, PECAM-1, EndoCAM, GPIIA', PECA1, PECAM1

1 Images
Flow Cytometry - Anti-CD31 antibody [B-B38] - BSA and Azide free (AB46922)
  • Flow Cyt

Unknown

Flow Cytometry - Anti-CD31 antibody [B-B38] - BSA and Azide free (AB46922)

Flow cytometry analysis staining CD31 in human platelet cells using ab27333.

This image was generated using the ascites version of the product.

This data was developed using the same antibody clone in a different buffer formulation.

  • 519 FITC

    FITC Anti-CD31 antibody [B-B38]

Key facts

Host species

Mouse

Clonality

Monoclonal

Clone number

B-B38

Isotype

IgG1

Light chain type

kappa

Carrier free

Yes

Reacts with

Human

Applications

Flow Cyt

applications

Immunogen

Recombinant Full Length Protein corresponding to Human PECAM1.

P16284

Specificity

This antibody is specific for CD31. Recognizes the soluble antigen

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Alternative Products

Primary Antibodies

AB222783

Anti-CD31 antibody [EPR17260-263]

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Anti-CD31 antibody [EPR17259]

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AB199734

Biotin Anti-CD31 antibody [EPR3094]

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  • 0
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Primary Antibodies

AB218582

Alexa Fluor® 647 Anti-CD31 antibody [EPR3094]

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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Alexa Fluor® 647 Anti-CD31 antibody [EPR3094] (AB218582)

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Complementary Products

Assay Kits

AB204527

Mouse CD31 ELISA Kit (PECAM1)

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Secondary Antibodies

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "<p><a href='/en-us/products/primary-antibodies/mouse-igg1-kappa-monoclonal-15-6e10a7-isotype-control-ab170190'>ab170190</a> - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.</p>" } } }
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Properties and storage information

Form
Liquid
Purification technique
Ion exchange chromatography
Purification notes
Sterile-filtered through 0.22 µm and treated to remove endotoxins. Carrier and preservative free.
Storage buffer
pH: 7.3 - 7.5 Constituents: PBS
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C|-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Cell adhesion molecule which is required for leukocyte transendothelial migration (TEM) under most inflammatory conditions (PubMed : 17580308, PubMed : 19342684). Tyr-690 plays a critical role in TEM and is required for efficient trafficking of PECAM1 to and from the lateral border recycling compartment (LBRC) and is also essential for the LBRC membrane to be targeted around migrating leukocytes (PubMed : 19342684). Trans-homophilic interaction may play a role in endothelial cell-cell adhesion via cell junctions (PubMed : 27958302). Heterophilic interaction with CD177 plays a role in transendothelial migration of neutrophils (PubMed : 17580308). Homophilic ligation of PECAM1 prevents macrophage-mediated phagocytosis of neighboring viable leukocytes by transmitting a detachment signal (PubMed : 12110892). Promotes macrophage-mediated phagocytosis of apoptotic leukocytes by tethering them to the phagocytic cells; PECAM1-mediated detachment signal appears to be disabled in apoptotic leukocytes (PubMed : 12110892). Modulates bradykinin receptor BDKRB2 activation (PubMed : 18672896). Regulates bradykinin- and hyperosmotic shock-induced ERK1/2 activation in endothelial cells (PubMed : 18672896). Induces susceptibility to atherosclerosis (By similarity).. Isoform Delta15. Does not protect against apoptosis.
See full target information PECAM1
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

International journal of molecular medicine 37:359-68 PubMed26707630

2015

Asymmetric stem-cell division ensures sustained keratinocyte hyperproliferation in psoriatic skin lesions.

Applications

Unspecified application

Species

Unspecified reactive species

Hai-Yan Jia,Ying Shi,Long-Fei Luo,Guan Jiang,Qiong Zhou,Shi-Zheng Xu,Tie-Chi Lei
View all publications
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Product promise

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