Rabbit Recombinant Monoclonal CD39 antibody. Suitable for WB and reacts with Mouse, Rat, Human samples. Cited in 19 publications.
Images
![Western blot - Anti-CD39 antibody [EPR3678(2)] (AB108248), expandable thumbnail](https://content.abcam.com/products/images/cd39-antibody-epr36782-ab108248--western-blot-img30179.jpg/_jcr_content/renditions/webp-475.webp "Western blot - Anti-CD39 antibody [EPR3678(2)] (AB108248)")
![Western blot - Anti-CD39 antibody [EPR3678(2)] (AB108248), expandable thumbnail](https://content.abcam.com/products/images/cd39-antibody-epr36782-ab108248--western-blot-img23364.jpg/_jcr_content/renditions/webp-475.webp "Western blot - Anti-CD39 antibody [EPR3678(2)] (AB108248)")
![Western blot - Anti-CD39 antibody [EPR3678(2)] (AB108248), expandable thumbnail](https://content.abcam.com/products/images/cd39-antibody-epr36782-ab108248--western-blot-img109644.jpg/_jcr_content/renditions/webp-475.webp "Western blot - Anti-CD39 antibody [EPR3678(2)] (AB108248)")
![Western blot - Anti-CD39 antibody [EPR3678(2)] (AB108248), expandable thumbnail](https://content.abcam.com/products/images/cd39-antibody-epr36782-ab108248--western-blot-img88863.jpg/_jcr_content/renditions/webp-475.webp "Western blot - Anti-CD39 antibody [EPR3678(2)] (AB108248)")
Publications
Filter by
- Clinical proteomics 20:392023Identification of potential molecular targets for the treatment of cluster 1 human pheochromocytoma and paraganglioma via comprehensive proteomic characterization.Applications:Unspecified applicationReactive species:Unspecified reactive speciesOndrej Vit,Pavel Talacko,Zdenek Musil,Igor Hartmann,Karel Pacak,Jiri PetrakPubMed 37749499
- mBio 14:e03459222023Epstein-Barr Virus-Positive Lymphomas Exploit Ectonucleotidase Activity To Limit Immune Responses and Prevent Cell Death.Applications:Unspecified applicationReactive species:Unspecified reactive speciesPhilip T Lange,Blossom DamaniaPubMed 36786572
- Annals of neurology 92:304-3212022Biallelic Variants in the Ectonucleotidase ENTPD1 Cause a Complex Neurodevelopmental Disorder with Intellectual Disability, Distinct White Matter Abnormalities, and Spastic Paraplegia.Applications:Unspecified applicationReactive species:Unspecified reactive speciesDaniel G Calame,Isabella Herman,Reza Maroofian,Aren E Marshall,Karina Carvalho Donis,Jawid M Fatih,Tadahiro Mitani,Haowei Du,Christopher M Grochowski,Sergio B Sousa,Charul Gijavanekar,Somayeh Bakhtiari,Yoko A Ito,Clarissa Rocca,Jill V Hunter,V Reid Sutton,Lisa T Emrick,Kym M Boycott,Alexander Lossos,Yakov Fellig,Eugenia Prus,Yosef Kalish,Vardiella Meiner,Manon Suerink,Claudia Ruivenkamp,Kayla Muirhead,Nebal W Saadi,Maha S Zaki,Arjan Bouman,Tahsin Stefan Barakat,David L Skidmore,Matthew Osmond,Thiago Oliveira Silva,David Murphy,Ehsan Ghayoor Karimiani,Yalda Jamshidi,Asaad Ghanim Jaddoa,Homa Tajsharghi,Sheng Chih Jin,Mohammad Reza Abbaszadegan,Reza Ebrahimzadeh-Vesal,Susan Hosseini,Shahryar Alavi,Amir Bahreini,Elahe Zarean,Mohammad Mehdi Salehi,Nouriya Abbas Al-Sannaa,Giovanni Zifarelli,Peter Bauer,Simon C Robson,Zeynep Coban-Akdemir,Lorena Travaglini,Francesco Nicita,Shalini N Jhangiani,Richard A Gibbs,Jennifer E Posey,Michael C Kruer,Kristin D Kernohan,Jonas A Morales Saute,Henry Houlden,Adeline Vanderver,Sarah H Elsea,Davut Pehlivan,Dana Marafi,James R LupskiPubMed 35471564
- Nature communications 13:16062022CRISPR activation screen identifies BCL-2 proteins and B3GNT2 as drivers of cancer resistance to T cell-mediated cytotoxicity.Applications:Unspecified applicationReactive species:Unspecified reactive speciesJulia Joung,Paul C Kirchgatterer,Ankita Singh,Jang H Cho,Suchita P Nety,Rebecca C Larson,Rhiannon K Macrae,Rebecca Deasy,Yuen-Yi Tseng,Marcela V Maus,Feng ZhangPubMed 35338135
- European journal of pain (London, England) 26:991-10052022Electroacupuncture relieves neuropathic pain by inhibiting degradation of the ecto-nucleotidase PAP in the dorsal root ganglions of CCI mice.Applications:Unspecified applicationReactive species:Unspecified reactive speciesXiaoxin Zhou,Wanbing Dai,Yi Qin,Siyi Qi,Yizhe Zhang,Weitian Tian,Xiyao Gu,Beijie Zheng,Jie Xiao,Weifeng Yu,Xuemei Chen,Diansan SuPubMed 35138669
- American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 21:2372-23862020Donor-derived regulatory dendritic cell infusion results in host cell cross-dressing and T cell subset changes in prospective living donor liver transplant recipients.Applications:Unspecified applicationReactive species:Unspecified reactive speciesCamila Macedo,Lillian M Tran,Alan F Zahorchak,Helong Dai,Xinyan Gu,Ranjithkumar Ravichandran,Thalachallour Mohanakumar,Beth Elinoff,Adriana Zeevi,Mindi A Styn,Abhinav Humar,Fadi G Lakkis,Diana M Metes,Angus W ThomsonPubMed 33171019
- Frontiers in immunology 10:25242019Toll-Like Receptor-Mediated Activation of CD39 Internalization in BMDCs Leads to Extracellular ATP Accumulation and Facilitates P2X7 Receptor Activation.Applications:Unspecified applicationReactive species:Unspecified reactive speciesRonglan Zhao et. al.PubMed 31736956
- PloS one 14:e02200942019Monitoring and characterizing soluble and membrane-bound ectonucleotidases CD73 and CD39.Applications:Unspecified applicationReactive species:Unspecified reactive speciesSaid A Goueli et. al.PubMed 31652269
- International journal of molecular medicine 44:1707-17182019Overexpressed CD39 mitigates sepsis‑induced kidney epithelial cell injury via suppressing the activation of NLR family pyrin domain containing 3.Applications:Unspecified applicationReactive species:Unspecified reactive speciesMeixia Yang et. al.PubMed 31545401
- PloS one 14:e02103082019Alopecia areata patients show deficiency of FOXP3+CD39+ T regulatory cells and clonotypic restriction of Treg TCRβ-chain, which highlights the immunopathological aspect of the disease.Applications:Unspecified applicationReactive species:Unspecified reactive speciesFatma N Hamed et. al.PubMed 31277078
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7.2 - 7.4
Preservative: 0.01% Sodium azide
Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA- Form
- Liquid
- Clonality
- Monoclonal
Immunogen
- The exact immunogen used to generate this antibody is proprietary information.
Reactivity data
Select an application| WB | ICC/IF | IHC-P | IP | Flow Cyt | |
|---|---|---|---|---|---|
| Human | Tested | Not recommended | Not recommended | Not recommended | Not recommended |
| Mouse | Tested | Not recommended | Not recommended | Not recommended | Not recommended |
| Rat | Tested | Not recommended | Not recommended | Not recommended | Not recommended |
WB
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Mouse | Dilution info 1/1000 - 1/10000 | Notes - |
Species Rat | Dilution info 1/1000 - 1/10000 | Notes - |
Species Human | Dilution info 1/1000 - 1/10000 | Notes - |
ICC/IF
Not recommendedNot recommended
| Species | Dilution info | Notes |
|---|---|---|
Species Human, Mouse, Rat | Dilution info - | Notes - |
IHC-P
Not recommendedNot recommended
| Species | Dilution info | Notes |
|---|---|---|
Species Human, Mouse, Rat | Dilution info - | Notes - |
IP
Not recommendedNot recommended
| Species | Dilution info | Notes |
|---|---|---|
Species Human, Rat, Mouse | Dilution info - | Notes - |
Flow Cyt
Not recommendedNot recommended
| Species | Dilution info | Notes |
|---|---|---|
Species Human, Mouse, Rat | Dilution info - | Notes - |
Associated Products
Select an associated product type
12 products for Alternative Product
Target data
Function
Catalyzes the hydrolysis of both di- and triphosphate nucleotides (NDPs and NTPs) and hydrolyze NTPs to nucleotide monophosphates (NMPs) in two distinct successive phosphate-releasing steps, with NDPs as intermediates and participates in the regulation of extracellular levels of nucleotides (Probable) (PubMed:8529670, PubMed:8626624, PubMed:8955160, PubMed:8996251). By hydrolyzing proinflammatory ATP and platelet-activating ADP to AMP, it blocks platelet aggregation and supports blood flow (PubMed:8955160, PubMed:8996251).
Alternative names
CD39, ENTPD1, Ectonucleoside triphosphate diphosphohydrolase 1, ATP diphosphohydrolase, Ecto-ATP diphosphohydrolase 1, Ecto-apyrase, Lymphoid cell activation antigen, Nucleoside triphosphate diphosphohydrolase 1, ATP-DPH, ATPDase, Ecto-ATPDase 1, Ecto-ATPase 1, NTPDase1
Recommended products
Rabbit Recombinant Monoclonal CD39 antibody. Suitable for WB and reacts with Mouse, Rat, Human samples. Cited in 19 publications.
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7.2 - 7.4
Preservative: 0.01% Sodium azide
Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA- Form
- Liquid
- Clonality
- Monoclonal
- Immunogen
- The exact immunogen used to generate this antibody is proprietary information.
- Clone number
- EPR3678(2)
- Purification technique
- Affinity purification Protein A
- Concentration
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage conditions
- +4°C
- Appropriate long-term storage conditions
- -20°C
- Storage information
- Stable for 12 months at -20°C
Notes
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free batch production
For more information, read more on recombinant antibodies.
Product promise
Tested
We have tested this species and application combination and it works. It is covered by our product promise.
Expected
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
Predicted
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
Not recommended
We do not recommend this combination. It is not covered by our product promise.
We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.
In the unlikely event of one of our products not working as expected, you are covered by our product promise.
Full details and terms and conditions can be found here:
Terms & Conditions.
4 product images
![Western blot - Anti-CD39 antibody [EPR3678(2)] (ab108248), expandable thumbnail](https://content.abcam.com/products/images/cd39-antibody-epr36782-ab108248--western-blot-img30179.jpg "Western blot - Anti-CD39 antibody [EPR3678(2)] (ab108248)")
Western blot - Anti-CD39 antibody [EPR3678(2)] (ab108248)
Blocking and diluting buffer and concentration 5% NFDM/TBST.
All lanes: Western blot - Anti-CD39 antibody [EPR3678(2)] (ab108248) at 1/1000 dilution
Lane 1: Rat hippocampus tissue lysate at 20 µg
Lane 2: Rat pancreas tissue lysate at 20 µg
SecondaryAll lanes: Western blot - Goat Anti-Rabbit IgG H&L (HRP) (Goat Anti-Rabbit IgG H&L (HRP) ab97051) at 1/20000 dilution
Predicted band size: 58 kDa
Observed band size: 70 kDa, 74 kDa
![Western blot - Anti-CD39 antibody [EPR3678(2)] (ab108248), expandable thumbnail](https://content.abcam.com/products/images/cd39-antibody-epr36782-ab108248--western-blot-img23364.jpg "Western blot - Anti-CD39 antibody [EPR3678(2)] (ab108248)")
Western blot - Anti-CD39 antibody [EPR3678(2)] (ab108248)
Blocking and diluting buffer and concentration 5% NFDM/TBST.
The PKC beta 2 recombinant protein is GST-tagged, so the molecular weight is higher.
All lanes: Western blot - Anti-CD39 antibody [EPR3678(2)] (ab108248) at 1/1000 dilution
Lane 1: Mouse placenta tissue lysate at 20 µg
Lane 2: Mouse urinary bladder tissue lysate at 20 µg
SecondaryAll lanes: Western blot - Goat Anti-Rabbit IgG H&L (HRP) (Goat Anti-Rabbit IgG H&L (HRP) ab97051) at 1/20000 dilution
Predicted band size: 58 kDa, 73 kDa
Observed band size: 70 kDa
Exposure time: 15s
![Western blot - Anti-CD39 antibody [EPR3678(2)] (ab108248), expandable thumbnail](https://content.abcam.com/products/images/cd39-antibody-epr36782-ab108248--western-blot-img109644.jpg "Western blot - Anti-CD39 antibody [EPR3678(2)] (ab108248)")
Western blot - Anti-CD39 antibody [EPR3678(2)] (ab108248)
Blocking and diluting buffer and concentration 5% NFDM/TBST.
Ref: PMID: 18693757
Lane 1: Western blot - Anti-CD39 antibody [EPR3678(2)] (ab108248) at 1/100 dilution
Lane 2: Western blot - Anti-CD39 antibody [EPR3678(2)] (ab108248) at 1/1000 dilution
All lanes: HUVEC whole cell lysate at 20 µg
SecondaryAll lanes: Western blot - Goat Anti-Rabbit IgG H&L (HRP) (Goat Anti-Rabbit IgG H&L (HRP) ab97051) at 1/20000 dilution
Predicted band size: 58 kDa
Observed band size: 70 kDa, 74 kDa
Exposure time: 3min
![Western blot - Anti-CD39 antibody [EPR3678(2)] (ab108248), expandable thumbnail](https://content.abcam.com/products/images/cd39-antibody-epr36782-ab108248--western-blot-img88863.jpg "Western blot - Anti-CD39 antibody [EPR3678(2)] (ab108248)")
Western blot - Anti-CD39 antibody [EPR3678(2)] (ab108248)
All lanes: Western blot - Anti-CD39 antibody [EPR3678(2)] (ab108248) at 1/1000 dilution
Lane 1: Human placenta lysate
Lane 2: IM-9 cell lysate
Predicted band size: 58 kDa
Downloads
Product protocols
- Visit the general protocols
- Visit troubleshooting
Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.
For licensing inquiries, please contact partnerships@abcam.com