AB178572

Anti-CD39 antibody [IMG17B5F11]

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(4 Publications)

Mouse Monoclonal CD39 antibody. Suitable for WB, IHC-P and reacts with Human, Mouse, Rat samples. Cited in 4 publications. Immunogen corresponding to Recombinant Fragment Protein within Human ENTPD1 aa 100-250.

View Alternative Names

CD39, ENTPD1, Ectonucleoside triphosphate diphosphohydrolase 1, ATP diphosphohydrolase, Ecto-ATP diphosphohydrolase 1, Ecto-apyrase, Lymphoid cell activation antigen, Nucleoside triphosphate diphosphohydrolase 1, ATP-DPH, ATPDase, Ecto-ATPDase 1, Ecto-ATPase 1, NTPDase1

2 Images

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD39 antibody [IMG17B5F11] (AB178572)

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD39 antibody [IMG17B5F11] (AB178572)

Immunohistochemical analysis of formalin-fixed, paraffin-embedded normal Human spleen tissue labeling CD39 with ab178572 at 5 μg/ml, followed by peroxidase-conjugate and DAB chromogen.

Western blot - Anti-CD39 antibody [IMG17B5F11] (AB178572)

WB

Supplier Data

Western blot - Anti-CD39 antibody [IMG17B5F11] (AB178572)

All lanes:

Western blot - Anti-CD39 antibody [IMG17B5F11] (ab178572) at 1 µg/mL

Lane 1:

Human brain lysate

Lane 2:

Mouse brain lysate

Lane 3:

Rat brain lysate

Lane 4:

Recombinant Human CD39 protein fragment

Predicted band size: 58 kDa

false

Key facts

Host species

Mouse

Clonality

Monoclonal

Clone number

IMG17B5F11

Isotype

IgG2b

Light chain type

lambda

Carrier free

No

Reacts with

Mouse, Rat, Human

Applications

IHC-P, WB

Immunogen

Recombinant Fragment Protein within Human ENTPD1 aa 100-250. The exact immunogen used to generate this antibody is proprietary information.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "0.5-5 µg/mL", "WB-species-notes": "<p></p>", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "5 µg/mL", "IHCP-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "0.5-5 µg/mL", "WB-species-notes": "<p></p>", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Rat": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "0.5-5 µg/mL", "WB-species-notes": "<p></p>", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" } } }

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Protein G

Storage buffer

pH: 7.4 Preservative: 0.05% Sodium azide Constituents: PBS, 0.05% BSA

Shipped at conditions

Blue Ice

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Catalyzes the hydrolysis of nucleoside triphosphates (NTPs) and diphosphates (NDPs) (Probable) (PubMed : 8529670, PubMed : 8626624, PubMed : 8955160, PubMed : 8996251). The enzyme sequentially removes phosphate groups in two successive steps, converting NTPs to nucleoside monophosphates (NMPs) via NDP intermediates (Probable) (PubMed : 8529670, PubMed : 8626624, PubMed : 8955160, PubMed : 8996251). This activity contributes to the regulation of extracellular levels of nucleotides (Probable) (PubMed : 8529670, PubMed : 8626624, PubMed : 8955160, PubMed : 8996251). By hydrolyzing proinflammatory ATP and platelet-activating ADP to AMP, it blocks platelet aggregation and supports blood flow (PubMed : 8955160, PubMed : 8996251).

See full target information ENTPD1

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Publications (4)

Recent publications for all applications. Explore the full list and refine your search

JCI insight 6: PubMed34283812

2021

PLA2G4A promotes right-sided colorectal cancer progression by inducing CD39+γδ Treg polarization.

Applications

Unspecified application

Species

Unspecified reactive species

Yang Zhan,Lei Zheng,Jia Liu,Dongzhi Hu,Junfeng Wang,Kai Liu,Jiansheng Guo,Ti Zhang,Dalu Kong

International journal of molecular sciences 22: PubMed34445661

2021

Anti-Inflammatory Effects of Endogenously Released Adenosine in Synovial Cells of Osteoarthritis and Rheumatoid Arthritis Patients.

Applications

Unspecified application

Species

Unspecified reactive species

Rebecca Sohn,Marius Junker,Andrea Meurer,Frank Zaucke,Rainer H Straub,Zsuzsa Jenei-Lanzl

Oncotarget 12:1580-1586 PubMed34381563

2021

High CD39 expression is associated with the non-muscle-invasive phenotype of human bladder cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Janaina Mendes Ferreira,Luiz Henrique Gomes Matheus,Renato Vasconcelos Souza de Almeida,Petronio Augusto de Souza Melo,Kátia Ramos Moreira Leite,Claudio Bovolenta Murta,Joaquim Francisco de Almeida Claro,Cleber Pinto Camacho,José Pontes-Júnior,Humberto Dellê

Respiratory research 19:103 PubMed29807526

2018

Is the purinergic pathway involved in the pathology of COPD? Decreased lung CD39 expression at initial stages of COPD.

Applications

Unspecified application

Species

Unspecified reactive species

Elisabet Aliagas,Mariana Muñoz-Esquerre,Ester Cuevas,Oriol Careta,Daniel Huertas,Marta López-Sánchez,Ignacio Escobar,Jordi Dorca,Salud Santos

View all publications

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Product promise

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