AB194998

Anti-CD4 antibody [KEN4]

Lab Essentials
What is this?

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(1 Publication)

Mouse Monoclonal CD4 antibody. Suitable for Flow Cyt and reacts with Rabbit samples. Cited in 1 publication. Immunogen corresponding to Cell preparation containing CD4 protein.

View Alternative Names

CD4, T-cell surface glycoprotein CD4, T-cell surface antigen T4/Leu-3

1 Images

Flow Cytometry - Anti-CD4 antibody [KEN4] (AB194998)

Flow Cyt

Supplier Data

Flow Cytometry - Anti-CD4 antibody [KEN4] (AB194998)

Flow cytometric analysis rabbit peripheral blood lymphocytes labeling CD4 with ab194998 at 1/25 dilution and Rabbit F(ab')2 anti-Mouse IgG FITC secondary antibody.

Key facts

Host species

Mouse

Clonality

Monoclonal

Clone number

KEN4

Isotype

IgG2a

Carrier free

Reacts with

Rabbit

Applications

Flow Cyt

applications

Immunogen

Cell preparation containing CD4 protein. The exact immunogen used to generate this antibody is proprietary information.

P46630

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Rabbit": { "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "1/25 - 1/200", "FlowCyt-species-notes": "<p><a href='/en-us/products/primary-antibodies/mouse-igg2c-kappa-monoclonal-18c8bc7ad10-isotype-control-ab170191'>ab170191</a> - Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody.</p>" } } }

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Protein G

Storage buffer

Preservative: 0.09% Sodium azide Constituents: PBS

Shipped at conditions

Blue Ice

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule : peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex. LCK then initiates different intracellular signaling pathways by phosphorylating various substrates ultimately leading to lymphokine production, motility, adhesion and activation of T-helper cells. In other cells such as macrophages or NK cells, plays a role in differentiation/activation, cytokine expression and cell migration in a TCR/LCK-independent pathway. Participates in the development of T-helper cells in the thymus and triggers the differentiation of monocytes into functional mature macrophages.

See full target information CD4

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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

PloS one 13:e0196571 PubMed29734357

2018

Cyclosporine a drug-delivery system for high-risk penetrating keratoplasty: Stabilizing the intraocular immune microenvironment.

Applications

Unspecified application

Species

Unspecified reactive species

Ting Zhang,Zhiyuan Li,Ting Liu,Suxia Li,Hua Gao,Chao Wei,Weiyun Shi

View all publications

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