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AB218628

Anti-CD4 antibody [OKT4]

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(2 Publications)

Mouse Monoclonal CD4 antibody. Suitable for Flow Cyt and reacts with Human samples. Cited in 2 publications.

View Alternative Names

CD4, T-cell surface glycoprotein CD4, T-cell surface antigen T4/Leu-3

  • 660 APC

    APC Anti-CD4 antibody [OKT4]

  • 578 PE

    PE Anti-CD4 antibody [OKT4]

  • 695 PerCP/Cy5.5®

    PerCP/Cy5.5® Anti-CD4 antibody [OKT4]

  • 519 FITC

    FITC Anti-CD4 antibody [OKT4]

Key facts

Host species

Mouse

Clonality

Monoclonal

Clone number

OKT4

Isotype

IgG2b

Light chain type

kappa

Carrier free

No

Reacts with

Human

Applications

Flow Cyt

applications

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Alternative Products

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "FlowCyt-species-checked": "guaranteed", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "<p></p>" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein A
Purification notes
ab218628 was purified from tissue culture supernatant via affinity chromatography. >90% pure as determined by SDS-PAGE analysis
Storage buffer
pH: 7.2 Preservative: 0.09% Sodium azide Constituents: 0.87% Sodium chloride, 0.12% Sodium dihydrogen phosphate
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule : peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex. LCK then initiates different intracellular signaling pathways by phosphorylating various substrates ultimately leading to lymphokine production, motility, adhesion and activation of T-helper cells. In other cells such as macrophages or NK cells, plays a role in differentiation/activation, cytokine expression and cell migration in a TCR/LCK-independent pathway. Participates in the development of T-helper cells in the thymus and triggers the differentiation of monocytes into functional mature macrophages.. (Microbial infection) Primary receptor for human immunodeficiency virus-1 (HIV-1) (PubMed : 12089508, PubMed : 16331979, PubMed : 2214026, PubMed : 9641677). Down-regulated by HIV-1 Vpu (PubMed : 17346169). Acts as a receptor for Human Herpes virus 7/HHV-7 (PubMed : 7909607).
See full target information CD4
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Publications (2)

Recent publications for all applications. Explore the full list and refine your search

Frontiers in immunology 16:1598436 PubMed40621452

2025

Tumor-suppressing multi-enterobacteria and PD-1/PD-L1 immune checkpoint inhibitor combination improves the outcome of hepatocellular carcinoma therapy.

Applications

Unspecified application

Species

Unspecified reactive species

Dongjuan Wu,Yaohua Fan,Mingsheng Zhang,Xiaoguang Wang,Xuesong He,Xinwei Guo,Yangchen Liu,Chenxi Cao,Zhaoqun Deng

Journal of leukocyte biology 100:1201-1211 PubMed27354409

2016

Protection of CD4+ T cells from hepatitis C virus infection-associated senescence via ΔNp63-miR-181a-Sirt1 pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Yun Zhou,Guang Y Li,Jun P Ren,Ling Wang,Juan Zhao,Shun B Ning,Ying Zhang,Jian Q Lian,Chang X Huang,Zhan S Jia,Jonathan P Moorman,Zhi Q Yao
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Product promise

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