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AB101530

Anti-CD4 antibody [SP35], prediluted

1

(1 Review)

|

(3 Publications)

Rabbit Recombinant Monoclonal CD4 antibody. Suitable for Flow Cyt, IHC-P and reacts with Human samples. Cited in 3 publications.

View Alternative Names

CD4, T-cell surface glycoprotein CD4, T-cell surface antigen T4/Leu-3

2 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD4 antibody [SP35], prediluted (AB101530)
  • IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD4 antibody [SP35], prediluted (AB101530)

Staining of Human CD4 in a Formalin/PFA-fixed paraffin-embedded section of Human T cell lymphoma using ab101530 at a dilution of 1/1.

Flow Cytometry - Anti-CD4 antibody [SP35], prediluted (AB101530)
  • Flow Cyt

Supplier Data

Flow Cytometry - Anti-CD4 antibody [SP35], prediluted (AB101530)

Flow cytometric analysis of rabbit anti-CD4 (SP35) antibody, prediluted, ab101530 in Jurkats cells (green) compared to negative control of rabbit IgG (blue)

Key facts

Host species

Rabbit

Clonality

Monoclonal

Clone number

SP35

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

IHC-P, Flow Cyt

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "<p><a href='/en-us/products/primary-antibodies/rabbit-igg-monoclonal-epr25a-isotype-control-ab172730'>ab172730</a> - Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.</p>", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "<p>Antigen retrieval is recommended: Boil tissue section in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min.</p>" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein A/G
Purification notes
Purified from TCS by protein A/G.
Storage buffer
pH: 7.6 Preservative: 0.1% Sodium azide Constituents: Tris buffered saline, 1% BSA
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C
Storage information
Do Not Freeze
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule : peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex. LCK then initiates different intracellular signaling pathways by phosphorylating various substrates ultimately leading to lymphokine production, motility, adhesion and activation of T-helper cells. In other cells such as macrophages or NK cells, plays a role in differentiation/activation, cytokine expression and cell migration in a TCR/LCK-independent pathway. Participates in the development of T-helper cells in the thymus and triggers the differentiation of monocytes into functional mature macrophages.. (Microbial infection) Primary receptor for human immunodeficiency virus-1 (HIV-1) (PubMed : 12089508, PubMed : 16331979, PubMed : 2214026, PubMed : 9641677). Down-regulated by HIV-1 Vpu (PubMed : 17346169). Acts as a receptor for Human Herpes virus 7/HHV-7 (PubMed : 7909607).
See full target information CD4
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Publications (3)

Recent publications for all applications. Explore the full list and refine your search

Frontiers in oncology 11:728437 PubMed34692503

2021

Case Report: Pulmonary Metastases From Epithelioid Sarcoma in Extremity Favourably Responding to Immunotherapy With Camrelizumab.

Applications

Unspecified application

Species

Unspecified reactive species

Tao-Jun Gong,Fan Tang,Chuan-Xi Zheng,Jie Wang,Yi-Tian Wang,Ya-Han Zhang,Yi Luo,Yong Zhou,Li Min,Chong-Qi Tu

Stem cells translational medicine 4:1450-62 PubMed26511651

2015

Subcutaneous Transplantation of Neural Precursor Cells in Experimental Autoimmune Encephalomyelitis Reduces Chemotactic Signals in the Central Nervous System.

Applications

Unspecified application

Species

Unspecified reactive species

Stylianos Ravanidis,Kyriaki Nepheli Poulatsidou,Roza Lagoudaki,Olga Touloumi,Elena Polyzoidou,Athanasios Lourbopoulos,Evangelia Nousiopoulou,Paschalis Theotokis,Evangelia Kesidou,Dimitrios Tsalikakis,Dimitrios Karacostas,Maria Grigoriou,Katerina Chlichlia,Nikolaos Grigoriadis

Clinical cancer research : an official journal of the American Association for Cancer Research 20:1125-34 PubMed24323902

2013

Surveillance of the tumor mutanome by T cells during progression from primary to recurrent ovarian cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Darin A Wick,John R Webb,Julie S Nielsen,Spencer D Martin,David R Kroeger,Katy Milne,Mauro Castellarin,Kwame Twumasi-Boateng,Peter H Watson,Rob A Holt,Brad H Nelson
View all publications
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