Rat Monoclonal CD41 antibody. Suitable for Flow Cyt and reacts with Mouse samples. Cited in 29 publications.
pH: 7.4
Preservative: 0.09% Sodium azide
Constituents: PBS
Flow Cyt | |
---|---|
Mouse | Expected |
Species | Dilution info | Notes |
---|---|---|
Species Mouse | Dilution info 1/50.00000 - 1/100.00000 | Notes Use 10μl of the suggested working dilution to label 106 cells in 100μl. |
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Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface.
CD41, Integrin alpha-IIb, GPalpha IIb, Platelet membrane glycoprotein IIb, GPIIb, Itga2b
Rat Monoclonal CD41 antibody. Suitable for Flow Cyt and reacts with Mouse samples. Cited in 29 publications.
pH: 7.4
Preservative: 0.09% Sodium azide
Constituents: PBS
ab33661 recognizes integrin alpha IIb subunit CD41
Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
The azide free version is ab94960.
Clone MWReg30 has been reported to inhibit PMA induced aggregation in vitro and to induce hypothermia in vivo.
We have tested this species and application combination and it works. It is covered by our product promise.
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
We do not recommend this combination. It is not covered by our product promise.
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