Rat Monoclonal CD41 antibody. Suitable for Flow Cyt and reacts with Mouse samples. Cited in 29 publications.
IgG1
Rat
pH: 7.4
Preservative: 0.09% Sodium azide
Constituents: PBS
Liquid
Monoclonal
| Flow Cyt | |
|---|---|
| Mouse | Expected |
| Species | Dilution info | Notes |
|---|---|---|
Species Mouse | Dilution info 1/50.00000 - 1/100.00000 | Notes Use 10μl of the suggested working dilution to label 106 cells in 100μl. |
Select an associated product type
Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface.
Integrin alpha-IIb, GPalpha IIb, Platelet membrane glycoprotein IIb, GPIIb, Itga2b
Rat Monoclonal CD41 antibody. Suitable for Flow Cyt and reacts with Mouse samples. Cited in 29 publications.
IgG1
Rat
pH: 7.4
Preservative: 0.09% Sodium azide
Constituents: PBS
Liquid
Monoclonal
MWReg30
Affinity purification Protein G
ab33661 recognizes integrin alpha IIb subunit CD41
Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Blue Ice
1-2 weeks
+4°C
-20°C
Upon delivery aliquot
The azide free version is ab94960.
Clone MWReg30 has been reported to inhibit PMA induced aggregation in vitro and to induce hypothermia in vivo.
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