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Rat Monoclonal CD41 antibody. Suitable for Flow Cyt and reacts with Mouse samples. Cited in 29 publications.


Publications

Key facts

Isotype
IgG1
Host species
Rat
Storage buffer

pH: 7.4
Preservative: 0.09% Sodium azide
Constituents: PBS

Form
Liquid
Clonality
Monoclonal

Reactivity data

Select an application
Product promiseTestedExpectedPredictedNot recommended
Flow Cyt
Mouse
Expected

Expected
Expected

Species
Mouse
Dilution info
1/50.00000 - 1/100.00000
Notes

Use 10μl of the suggested working dilution to label 106 cells in 100μl.

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1 product for Alternative Version

Target data

Function

Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface.

Alternative names

Recommended products

Rat Monoclonal CD41 antibody. Suitable for Flow Cyt and reacts with Mouse samples. Cited in 29 publications.

Key facts

Isotype
IgG1
Form
Liquid
Clonality
Monoclonal
Clone number
MWReg30
Purification technique
Affinity purification Protein G
Specificity

ab33661 recognizes integrin alpha IIb subunit CD41

Concentration
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Purification notes

Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant

Storage

Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot

Notes

The azide free version is ab94960.

Clone MWReg30 has been reported to inhibit PMA induced aggregation in vitro and to induce hypothermia in vivo.

Product promise

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