AB3105

Anti-CD90 / Thy1 antibody [IBL-6/23]

Name: Anti-CD90 / Thy1 antibody [IBL-6/23] Rat monoclonal (ab3105) | Abcam
Brand: Abcam Limited
SKU: AB3105
Price: 605 USD
Availability: InStock
Rating: 4 (3 reviews)

(3 Reviews)

(43 Publications)

Rat Monoclonal CD90 / Thy1 antibody. Suitable for IHC-P, Flow Cyt, IHC-FoFr and reacts with Mouse samples. Cited in 43 publications. Immunogen corresponding to Full Length Protein corresponding to Mouse Thy1.

View Alternative Names

CD90, Thy-1, Thy1, Thy-1 membrane glycoprotein, Thy-1 antigen

2 Images

Flow Cytometry - Anti-CD90 / Thy1 antibody [IBL-6/23] (AB3105)

Flow Cyt

Supplier Data

Flow Cytometry - Anti-CD90 / Thy1 antibody [IBL-6/23] (AB3105)

Flow cytometry analysis of mouse peripheral lymph node labeling CD90 / Thy1 with ab3105 at 5 ug/mL.

PE-conjugated anti-rat IgG.

Red line : isotype control labeling with <3% postive events.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD90 / Thy1 antibody [IBL-6/23] (AB3105)

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD90 / Thy1 antibody [IBL-6/23] (AB3105)

Immunohistochemistry (Formalin/PFA-fixed paraffiin-embedded sections) analysis of mouse spleen tissue labelling CD90 / Thy1 with ab3105 at 1/100. Antigen retrieval was heat-mediated with citrate buffer pH 6.0.

Key facts

Host species

Rat

Clonality

Monoclonal

Clone number

IBL-6/23

Isotype

IgG1

Light chain type

kappa

Carrier free

Reacts with

Mouse

Applications

IHC-P, IHC-FoFr, Flow Cyt

applications

Immunogen

Full Length Protein corresponding to Mouse Thy1. The exact immunogen used to generate this antibody is proprietary information.

P01831

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"}, "IHCFoFr" : {"fullname" : "Immunohistochemistry (PFA perfusion fixed frozen sections)", "shortname":"IHC-FoFr"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Mouse": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": " Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.", "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "5 µg/mL", "FlowCyt-species-notes": "", "IHCFoFr-species-checked": "guaranteed", "IHCFoFr-species-dilution-info": "", "IHCFoFr-species-notes": "" } } }

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Protein G

Storage buffer

Preservative: 0.09% Sodium azide Constituents: 1% BSA

Shipped at conditions

Blue Ice

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Storage information

Avoid freeze / thaw cycle

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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

CD90 also known as Thy1 is a glycoprotein with a molecular mass of approximately 25-37 kDa. It is highly conserved across species and found on the surface of various cell types including fibroblasts neurons and endothelial cells. CD90 is expressed in these cells in tissues such as the brain thymus and lungs. Researchers use anti-CD90 antibodies for detection often in combination with CD90 FITC in immunofluorescence assays. CD90 serves as a useful cell marker particularly in identifying mesenchymal stem cells (MSCs).

Biological function summary

CD90 plays a role in cell-cell and cell-matrix interactions contributing to cellular adhesion migration and signal transduction. It functions as part of a complex involving integrins which mediate its interaction with the extracellular matrix. This protein also influences T-cell activation reflecting its importance in immune response regulation. Its presence aids in modulating response to injury and promoting tissue repair due to its association with stem and progenitor cells.

Pathways

CD90 engagement affects focal adhesion and MAPK signaling pathways. It interacts with integrins like αvβ3 and α5β1 influencing cell movement and proliferation processes. CD90 involvement in these pathways allows it to regulate responses important for cell survival and communication within various tissues. These interactions highlight the protein's role in maintaining cellular homeostasis and regulating physiological processes.

CD90 has associations with fibrosis and cancer. In fibrotic conditions CD90 expression affects fibroblast activity influencing tissue scarring in organs such as the liver and lungs. In cancer CD90 modifies tumor progression and metastasis by impacting cell adhesion and migration with connections to proteins like TGF-beta which further drive these processes. Understanding CD90 in disease contexts facilitates the development of therapeutic strategies aimed at modulating its activity.

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

May play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain.

See full target information Thy1

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Publications (43)

Recent publications for all applications. Explore the full list and refine your search

eLife 13: PubMed39692737

2024

Rejuvenating aged osteoprogenitors for bone repair.

Applications

Unspecified application

Species

Unspecified reactive species

Joshua Reeves,Pierre Tournier,Pierre Becquart,Robert Carton,Yin Tang,Alessandra Vigilante,Dong Fang,Shukry J Habib

Molecular carcinogenesis 64:215-220 PubMed39513649

2024

CAF Specific Expression of Podoplanin May Be Dispensable for the Malignancy of Malignant Melanoma.

Applications

Unspecified application

Species

Unspecified reactive species

Saskia Tauch,Bettina Kast,Sabrina Lohr,Lowis Kemm,Melanie Sator-Schmitt,Nicolas Gengenbacher,Hellmut G Augustin,Peter Angel

Nature communications 15:9071 PubMed39433776

2024

Polyphenol-mediated redox-active hydrogel with HS gaseous-bioelectric coupling for periodontal bone healing in diabetes.

Applications

Unspecified application

Species

Unspecified reactive species

Xinyi Fang,Jun Wang,Chengxinyue Ye,Jiu Lin,Jinhui Ran,Zhanrong Jia,Jinglei Gong,Yiming Zhang,Jie Xiang,Xiong Lu,Chaoming Xie,Jin Liu

Bioactive materials 43:82-97 PubMed39345992

2024

Ultrasound-generated bubbles enhance osteogenic differentiation of mesenchymal stromal cells in composite collagen hydrogels.

Applications

Unspecified application

Species

Unspecified reactive species

Somnath Maji,Mitra Aliabouzar,Carole Quesada,Anjali Chiravuri,Aidan Macpherson,Abigail Pinch,Karsyn Kazyak,Ziyad Emara,Bachir A Abeid,Robert N Kent,Firaol S Midekssa,Man Zhang,Brendon M Baker,Renny T Franceschi,Mario L Fabiilli

Communications biology 6:1120 PubMed37925525

2023

LncRNA SNHG14 activates autophagy via regulating miR-493-5p/Mef2c axis to alleviate osteoporosis progression.

Applications

Unspecified application

Species

Unspecified reactive species

Jingbo Xue,Lulu Liu,Hao Liu,Zepeng Li

Frontiers in microbiology 14:1126896 PubMed37032878

2023

Immune profiling of experimental murine mastitis reveals conserved response to mammary pathogenic , , and .

Applications

Unspecified application

Species

Unspecified reactive species

Peleg Schneider,Hagit Salamon,Nathalie Weizmann,Einat Nissim-Eliraz,Inna Lysnyansky,Nahum Y Shpigel

Journal of orthopaedic surgery and research 18:168 PubMed36872331

2023

TGM2 accelerates migration and differentiation of BMSCs by activating Wnt/β-catenin signaling.

Applications

Unspecified application

Species

Unspecified reactive species

Feng Liu,Mingzheng Wu,Xixia Wu,Dan Chen,Ming Xie,Hao Pan

Cell reports 41:111853 PubMed36543145

2022

Nail-associated mesenchymal cells contribute to and are essential for dorsal digit tip regeneration.

Applications

Unspecified application

Species

Unspecified reactive species

Neemat Mahmud,Christine Eisner,Sruthi Purushothaman,Mekayla A Storer,David R Kaplan,Freda D Miller

Disease markers 2022:6943630 PubMed36072901

2022

Kartogenin Induced Adipose-Derived Stem Cell Exosomes Enhance the Chondrogenic Differentiation Ability of Adipose-Derived Stem Cells.

Applications

Unspecified application

Species

Unspecified reactive species

Aiguo Xie,Jixin Xue,Yuting Wang,Chao Yang,Miao Xu,Yongkang Jiang

Cells 11: PubMed35883695

2022

Therapeutic Potential of Human Immature Dental Pulp Stem Cells Observed in Mouse Model for Acquired Aplastic Anemia.

Applications

Unspecified application

Species

Unspecified reactive species

Vivian Fonseca Gonzaga,Cristiane Valverde Wenceslau,Daniel Perez Vieira,Bruna de Oliveira Policiquio,Charbel Khalil,Rodrigo Pinheiro Araldi,Irina Kerkis

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-CD90 / Thy1 antibody [IBL-6/23]

Flow Cytometry - Anti-CD90 / Thy1 antibody [IBL-6/23] (AB3105)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD90 / Thy1 antibody [IBL-6/23] (AB3105)

Key facts

Host species

Clonality

Clone number

Isotype

Light chain type

Carrier free

Reacts with

Applications

Immunogen

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Reactivity data

Properties and storage information

Form

Purification technique

Storage buffer

Shipped at conditions

Appropriate short-term storage duration

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Storage information

Supplementary information

Biological function summary

Pathways

Product protocols

Target data

Publications (43)

Product promise