Rabbit Polyclonal CDCA7L/HR1 antibody. Suitable for IP, WB and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Synthetic Peptide within Human CDCA7L.
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Publications
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- Molecular medicine reports 20:1149-11562019CDCA7L promotes glioma proliferation by targeting CCND1 and predicts an unfavorable prognosis.Applications:Unspecified applicationReactive species:Unspecified reactive speciesQian-Kun Ji et. al.PubMed 31173217
- Pathology, research and practice 215:50-562018Cell division cycle associated 7 like predicts unfavorable prognosis and promotes invasion in glioma.Applications:Unspecified applicationReactive species:Unspecified reactive speciesFa-Zheng Shen,Xiang-Sheng Li,Ji-Wei Ma,Xiang-Yang Wang,Shu-Peng Zhao,Lei Meng,Shu-Feng Liang,Xin-Li ZhaoPubMed 30389317
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 6.8 - 7.4
Preservative: 0.09% Sodium azide
Constituents: Tris buffered saline, 0.1% BSA- Form
- Liquid
- Clonality
- Polyclonal
Immunogen
- Synthetic Peptide within Human CDCA7L. The exact immunogen used to generate this antibody is proprietary information. Database link Q96GN5
Reactivity data
Select an application| IP | WB | |
|---|---|---|
| Human | Tested | Tested |
| Chimpanzee | Predicted | Predicted |
| Gorilla | Predicted | Predicted |
| Orangutan | Predicted | Predicted |
| Rhesus monkey | Predicted | Predicted |
IP
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info 2.00000-5.00000 µg/mg of lysate | Notes - |
PredictedPredicted
| Species | Dilution info | Notes |
|---|---|---|
Species Chimpanzee, Gorilla, Orangutan, Rhesus monkey | Dilution info - | Notes - |
WB
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info 1/2000.00000 - 1/10000.00000 | Notes - |
PredictedPredicted
| Species | Dilution info | Notes |
|---|---|---|
Species Chimpanzee, Gorilla, Orangutan, Rhesus monkey | Dilution info - | Notes - |
Target data
Function
Plays a role in transcriptional regulation as a repressor that inhibits monoamine oxidase A (MAOA) activity and gene expression by binding to the promoter. Plays an important oncogenic role in mediating the full transforming effect of MYC in medulloblastoma cells. Involved in apoptotic signaling pathways; May act downstream of P38-kinase and BCL-2, but upstream of CASP3/caspase-3 as well as CCND1/cyclin D1 and E2F1.
Alternative names
HR1, JPO2, R1, CDCA7L, Cell division cycle-associated 7-like protein, Protein JPO2, Transcription factor RAM2
Recommended products
Rabbit Polyclonal CDCA7L/HR1 antibody. Suitable for IP, WB and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Synthetic Peptide within Human CDCA7L.
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 6.8 - 7.4
Preservative: 0.09% Sodium azide
Constituents: Tris buffered saline, 0.1% BSA- Form
- Liquid
- Clonality
- Polyclonal
- Immunogen
- Synthetic Peptide within Human CDCA7L. The exact immunogen used to generate this antibody is proprietary information. Database link Q96GN5
- Purification technique
- Affinity purification Immunogen
- Concentration
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage conditions
- +4°C
- Appropriate long-term storage conditions
- -20°C
- Aliquoting information
- Upon delivery aliquot
- Storage information
- Avoid freeze / thaw cycle
Product promise
Tested
We have tested this species and application combination and it works. It is covered by our product promise.
Expected
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
Predicted
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
Not recommended
We do not recommend this combination. It is not covered by our product promise.
We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.
In the unlikely event of one of our products not working as expected, you are covered by our product promise.
Full details and terms and conditions can be found here:
Terms & Conditions.
2 product images
Western blot - Anti-CDCA7L/HR1 antibody (ab70637)
All lanes: Western blot - Anti-CDCA7L/HR1 antibody (ab70637) at 0.04 µg/mL
Lane 1: HeLa whole cell lysate at 50 µg
Lane 2: HeLa whole cell lysate at 15 µg
Lane 3: HeLa whole cell lysate at 5 µg
Lane 4: 293T whole cell lysate at 50 µg
Developed using the ECL technique.
Predicted band size: 52 kDa
Observed band size: 110 kDa, 130 kDa, 53 kDa, 70 kDa
Exposure time: 30s
Immunoprecipitation - Anti-CDCA7L/HR1 antibody (ab70637)
Detection of CDCA7L/HR1 by Western Blot of Immunprecipitate. ab70637 at 1μg/ml staining CDCA7L/HR1 in HeLa whole cell lysate immunoprecipitated using ab70637 at 3μg/mg lysate (1 mg/IP; 20% of IP loaded/lane). Detection: chemiluminescence with exposure time of 30 seconds.
All lanes: Immunoprecipitation - Anti-CDCA7L/HR1 antibody (ab70637)
Predicted band size: 52 kDa
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