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AB70637

Anti-CDCA7L/HR1 antibody

4

(3 Reviews)

|

(3 Publications)

Rabbit Polyclonal CDCA7L/HR1 antibody. Suitable for IP, WB and reacts with Human samples. Cited in 3 publications. Immunogen corresponding to Synthetic Peptide within Human CDCA7L.

View Alternative Names

HR1, JPO2, R1, CDCA7L, Cell division cycle-associated 7-like protein, Protein JPO2, Transcription factor RAM2

2 Images
Immunoprecipitation - Anti-CDCA7L/HR1 antibody (AB70637)
  • IP

Unknown

Immunoprecipitation - Anti-CDCA7L/HR1 antibody (AB70637)

Detection of CDCA7L/HR1 by Western Blot of Immunprecipitate. ab70637 at 1μg/ml staining CDCA7L/HR1 in HeLa whole cell lysate immunoprecipitated using ab70637 at 3μg/mg lysate (1 mg/IP; 20% of IP loaded/lane). Detection : chemiluminescence with exposure time of 30 seconds.

All lanes:

Immunoprecipitation - Anti-CDCA7L/HR1 antibody (ab70637)

Predicted band size: 52 kDa

false

Western blot - Anti-CDCA7L/HR1 antibody (AB70637)
  • WB

Unknown

Western blot - Anti-CDCA7L/HR1 antibody (AB70637)

All lanes:

Western blot - Anti-CDCA7L/HR1 antibody (ab70637) at 0.04 µg/mL

Lane 1:

HeLa whole cell lysate at 50 µg

Lane 2:

HeLa whole cell lysate at 15 µg

Lane 3:

HeLa whole cell lysate at 5 µg

Lane 4:

293T whole cell lysate at 50 µg

Predicted band size: 52 kDa

Observed band size: 110 kDa,130 kDa,53 kDa,70 kDa

true

Exposure time: 30s

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

IP, WB

applications

Immunogen

Synthetic Peptide within Human CDCA7L. The exact immunogen used to generate this antibody is proprietary information.

Q96GN5

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IP" : {"fullname" : "Immunoprecipitation", "shortname":"IP"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IP-species-checked": "testedAndGuaranteed", "IP-species-dilution-info": "2-5 µg/mg of lysate", "IP-species-notes": "<p></p>", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/2000 - 1/10000", "WB-species-notes": "<p></p>" }, "Chimpanzee": { "IP-species-checked": "predicted", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Gorilla": { "IP-species-checked": "predicted", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Orangutan": { "IP-species-checked": "predicted", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Rhesus monkey": { "IP-species-checked": "predicted", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 6.8 - 7.4 Preservative: 0.09% Sodium azide Constituents: Tris buffered saline, 0.1% BSA
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Plays a role in transcriptional regulation as a repressor that inhibits monoamine oxidase A (MAOA) activity and gene expression by binding to the promoter. Plays an important oncogenic role in mediating the full transforming effect of MYC in medulloblastoma cells. Involved in apoptotic signaling pathways; May act downstream of P38-kinase and BCL-2, but upstream of CASP3/caspase-3 as well as CCND1/cyclin D1 and E2F1.
See full target information CDCA7L
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Publications (3)

Recent publications for all applications. Explore the full list and refine your search

BioFactors (Oxford, England) 47:865-878 PubMed34339079

2021

CDCA7-regulated inflammatory mechanism through TLR4/NF-κB signaling pathway in stomach adenocarcinoma.

Applications

Unspecified application

Species

Unspecified reactive species

Yu Guo,Kaimei Zhou,Xiang Zhuang,Junjie Li,Xianglin Shen

Molecular medicine reports 20:1149-1156 PubMed31173217

2019

CDCA7L promotes glioma proliferation by targeting CCND1 and predicts an unfavorable prognosis.

Applications

Unspecified application

Species

Unspecified reactive species

Qian-Kun Ji,Ji-Wei Ma,Rui-Hua Liu,Xiang-Sheng Li,Fa-Zheng Shen,Li-Yong Huang,Lei Hui,Yan-Juan Ma,Bao-Zhe Jin

Pathology, research and practice 215:50-56 PubMed30389317

2018

Cell division cycle associated 7 like predicts unfavorable prognosis and promotes invasion in glioma.

Applications

Unspecified application

Species

Unspecified reactive species

Fa-Zheng Shen,Xiang-Sheng Li,Ji-Wei Ma,Xiang-Yang Wang,Shu-Peng Zhao,Lei Meng,Shu-Feng Liang,Xin-Li Zhao
View all publications
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Product promise

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