AB181860

Anti-CDH12 antibody [EPR14164]

RabMAb
Recombinant
What is this?

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(4 Publications)

Rabbit Recombinant Monoclonal CDH12 antibody. Suitable for IP, WB and reacts with Human samples. Cited in 4 publications.

View Alternative Names

Cadherin-12, Brain cadherin, Neural type cadherin 2, BR-cadherin, N-cadherin 2, CDH12

2 Images

Supplier Data

Immunoprecipitation - Anti-CDH12 antibody [EPR14164] (AB181860)

Western blot analysis of immunoprecipitation pellet from Human fetal heart lysate immunoprecipitated using ab181860 at 1/40 dilution.

Secondary : Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugate at 1/1000 dilution.

All lanes:

Immunoprecipitation - Anti-CDH12 antibody [EPR14164] (ab181860)

Predicted band size: 88 kDa

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Supplier Data

Western blot - Anti-CDH12 antibody [EPR14164] (AB181860)

All lanes:

Western blot - Anti-CDH12 antibody [EPR14164] (ab181860) at 1/20000 dilution

Lane 1:

Human fetal brain lysate at 10 µg

Lane 2:

Human fetal heart lysate at 10 µg

Secondary

All lanes:

Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugate at 1/1000 dilution

Predicted band size: 88 kDa

false

Key facts

Host species

Rabbit

Clonality

Monoclonal

Clone number

EPR14164

Isotype

IgG

Carrier free

Reacts with

Human

Applications

IP, WB

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IP" : {"fullname" : "Immunoprecipitation", "shortname":"IP"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IP-species-checked": "testedAndGuaranteed", "IP-species-dilution-info": "1/40", "IP-species-notes": "<p></p>", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/10000 - 1/50000", "WB-species-notes": "<p></p>" }, "Mouse": { "IP-species-checked": "predicted", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Rat": { "IP-species-checked": "predicted", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" } } }

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Product details

Patented technology
Our RabMAb^® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb^® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production

For more information, read more on recombinant antibodies.

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Properties and storage information

Form

Liquid

Purity

Tissue culture supernatant

Storage buffer

Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA

Shipped at conditions

Blue Ice

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.

See full target information Cadherin-12

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Publications (4)

Recent publications for all applications. Explore the full list and refine your search

Cancer cell international 21:2 PubMed33397384

2021

Histone methyltransferase SUV39H2 regulates LSD1-dependent CDH1 expression and promotes epithelial mesenchymal transition of osteosarcoma.

Applications

Unspecified application

Species

Unspecified reactive species

Yingying Miao,Guifeng Liu,Lin Liu

Journal of experimental & clinical cancer research 39:202 PubMed32993749

2020

FadA promotes DNA damage and progression of Fusobacterium nucleatum-induced colorectal cancer through up-regulation of chk2.

Applications

Unspecified application

Species

Unspecified reactive species

Pin Guo,Zibin Tian,Xinjuan Kong,Lin Yang,Xinzhi Shan,Bingzi Dong,Xueli Ding,Xue Jing,Chen Jiang,Na Jiang,Yanan Yu

Medical science monitor : international medical jo 23:640-648 PubMed28159956

2017

MicroRNA-495 Inhibits Gastric Cancer Cell Migration and Invasion Possibly via Targeting High Mobility Group AT-Hook 2 (HMGA2).

Applications

Unspecified application

Species

Unspecified reactive species

Huashe Wang,Zhipeng Jiang,Honglei Chen,Xiaobin Wu,Jun Xiang,Junsheng Peng

Oncology reports 26:101-8 PubMed21573496

2011

CDH12 promotes the invasion of salivary adenoid cystic carcinoma.

Applications

Unspecified application

Species

Unspecified reactive species

Jin-Feng Wang,Lin She,Bo-Hua Su,Lin-Can Ding,Fei-Fei Zheng,Da-Li Zheng,You-Guang Lu

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-CDH12 antibody [EPR14164]

Immunoprecipitation - Anti-CDH12 antibody [EPR14164] (AB181860)

Western blot - Anti-CDH12 antibody [EPR14164] (AB181860)

Key facts

Host species

Clonality

Clone number

Isotype

Carrier free

Reacts with

Applications

Immunogen

Reactivity data

Product details

Properties and storage information

Form

Purity

Storage buffer

Shipped at conditions

Appropriate short-term storage duration

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Aliquoting information

Storage information

Product protocols

Target data

Publications (4)

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Product promise