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AB251955

Anti-CDK13 antibody

4

(1 Review)

|

(3 Publications)

Rabbit Polyclonal CDK13 antibody. Suitable for ICC/IF and reacts with Human samples. Cited in 3 publications. Immunogen corresponding to Recombinant Fragment Protein within Human CDK13 aa 1150-1300.

View Alternative Names

CDC2L, CDC2L5, CHED, KIAA1791, CDK13, Cyclin-dependent kinase 13, CDC2-related protein kinase 5, Cell division cycle 2-like protein kinase 5, Cell division protein kinase 13, Cholinesterase-related cell division controller, hCDK13

1 Images
Immunocytochemistry/ Immunofluorescence - Anti-CDK13 antibody (AB251955)
  • ICC/IF

Unknown

Immunocytochemistry/ Immunofluorescence - Anti-CDK13 antibody (AB251955)

PFA-fixed, Triton X-100 permeabilized HeLa (human epithelial cell line from cervix adenocarcinoma) cells stained for CDK13 (green) using ab251955 at 4 μg/ml in ICC/IF.

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

ICC/IF

applications

Immunogen

Recombinant Fragment Protein within Human CDK13 aa 1150-1300. The exact immunogen used to generate this antibody is proprietary information.

Q14004

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Secondary Antibodies

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Primary Antibodies

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "0.25-2 µg/mL", "ICCIF-species-notes": "<p>Fixation/Permeabilization: PFA/Triton X-100.</p>" }, "Mouse": { "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Cow": { "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine)
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Cyclin-dependent kinase which displays CTD kinase activity and is required for RNA splicing. Has CTD kinase activity by hyperphosphorylating the C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit RPB1, thereby acting as a key regulator of transcription elongation. Required for RNA splicing, probably by phosphorylating SRSF1/SF2. Required during hematopoiesis. In case of infection by HIV-1 virus, interacts with HIV-1 Tat protein acetylated at 'Lys-50' and 'Lys-51', thereby increasing HIV-1 mRNA splicing and promoting the production of the doubly spliced HIV-1 protein Nef.
See full target information CDK13
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Publications (3)

Recent publications for all applications. Explore the full list and refine your search

Molecular cancer 20:115 PubMed34496885

2021

An ADAR1-dependent RNA editing event in the cyclin-dependent kinase CDK13 promotes thyroid cancer hallmarks.

Applications

Unspecified application

Species

Unspecified reactive species

Julia Ramírez-Moya,Christos Miliotis,Allison R Baker,Richard I Gregory,Frank J Slack,Pilar Santisteban

Acta neuropathologica 141:681-696 PubMed33609158

2021

Distinct amyloid-β and tau-associated microglia profiles in Alzheimer's disease.

Applications

Unspecified application

Species

Unspecified reactive species

Emma Gerrits,Nieske Brouwer,Susanne M Kooistra,Maya E Woodbury,Yannick Vermeiren,Mirjam Lambourne,Jan Mulder,Markus Kummer,Thomas Möller,Knut Biber,Wilfred F A den Dunnen,Peter P De Deyn,Bart J L Eggen,Erik W G M Boddeke

Cell reports 34:108670 PubMed33503434

2021

Inflammation-driven deaminase deregulation fuels human pre-leukemia stem cell evolution.

Applications

Unspecified application

Species

Unspecified reactive species

Qingfei Jiang,Jane Isquith,Luisa Ladel,Adam Mark,Frida Holm,Cayla Mason,Yudou He,Phoebe Mondala,Isabelle Oliver,Jessica Pham,Wenxue Ma,Eduardo Reynoso,Shawn Ali,Isabella Jamieson Morris,Raymond Diep,Chanond Nasamran,Guorong Xu,Roman Sasik,Sara Brin Rosenthal,Amanda Birmingham,Sanja Coso,Gabriel Pineda,Leslie Crews,Mary E Donohoe,J Craig Venter,Thomas Whisenant,Ruben A Mesa,Ludmil B Alexandrov,Kathleen M Fisch,Catriona Jamieson
View all publications
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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

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