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Mouse Monoclonal p16INK4A antibody. Suitable for IHC-P and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human CDKN2A.

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Images

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CDKN2A/p16INK4a antibody [JC2] (AB267833), expandable thumbnail
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CDKN2A/p16INK4a antibody [JC2] (AB267833), expandable thumbnail
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CDKN2A/p16INK4a antibody [JC2] (AB267833), expandable thumbnail
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CDKN2A/p16INK4a antibody [JC2] (AB267833), expandable thumbnail

Publications

Key facts

Isotype
IgG2a
Host species
Mouse
Storage buffer

pH: 7.3 - 7.5
Preservative: 0.099% Sodium azide
Constituents: Tissue culture supernatant

Form
Liquid
Clonality
Monoclonal

Immunogen

  • Recombinant Full Length Protein corresponding to Human CDKN2A. Database link P42771

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Reactivity data

Select an application
Product promiseTestedExpectedPredictedNot recommended
IHC-P
Human
Tested

Tested
Tested

Species
Human
Dilution info
1/50.00000 - 1/100.00000
Notes

Antigen retrieval: EDTA buffer pH 8.0. Tissue fixed in 10% formalin are suitable for use prior to paraffin embedding.

Incubate with primary antibody for 30 mins at RT.

Associated Products

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Target data

Function

The protein expressed by the gene CDKN2A acts as a negative regulator of normal cell proliferation by strongly interacting with CDK4 and CDK6. This interaction inhibits the ability of CDK4 and CDK6 to interact with cyclins D and to phosphorylate the retinoblastoma protein. This supplementary information is collated from multiple sources and compiled automatically.

Alternative names

CDKN2, MTS1, CDKN2A, Cyclin-dependent kinase inhibitor 2A, Cyclin-dependent kinase 4 inhibitor A, Multiple tumor suppressor 1, p16-INK4a, CDK4I, MTS-1, p16-INK4, p16INK4A

Recommended products

Mouse Monoclonal p16INK4A antibody. Suitable for IHC-P and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human CDKN2A.

Key facts

Isotype
IgG2a
Form
Liquid
Clonality
Monoclonal
Immunogen
  • Recombinant Full Length Protein corresponding to Human CDKN2A. Database link P42771
Clone number
JC2
Purity
Tissue culture supernatant
Concentration
Loading...

Storage

Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle

Product promise

We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.

In the unlikely event of one of our products not working as expected, you are covered by our product promise.

Full details and terms and conditions can be found here:
Terms & Conditions.

4 product images

  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CDKN2A/p16INK4a antibody [JC2] (ab267833), expandable thumbnail

    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CDKN2A/p16INK4a antibody [JC2] (ab267833)

    Formalin-fixed, parafin-embedded high-grade squamous intraepithelial (HSIL) lesions stained for CDKN2A/p16INK4a using ab267833 at 1/50 dilution for 30 minutes at room temperature. Antigen retrieval was performed using TEDTA buffer pH 8 and blue Hematoxylin was used as a counter stain.

  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CDKN2A/p16INK4a antibody [JC2] (ab267833), expandable thumbnail

    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CDKN2A/p16INK4a antibody [JC2] (ab267833)

    Formalin-fixed, parafin-embedded human uterine cervical squamous cell carcinoma tissue stained for CDKN2A/p16INK4a using ab267833 at 1/50 dilution for 30 minutes at room temperature. Antigen retrieval was performed using TEDTA buffer pH 8 and blue Hematoxylin was used as a counter stain.

  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CDKN2A/p16INK4a antibody [JC2] (ab267833), expandable thumbnail

    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CDKN2A/p16INK4a antibody [JC2] (ab267833)

    Formalin-fixed, parafin-embedded tonsil tissue stained for CDKN2A/p16INK4a using ab267833 at 1/50 dilution for 30 minutes at room temperature. Antigen retrieval was performed using TEDTA buffer pH 8 and blue Hematoxylin was used as a counter stain. Scatter epithelial cells display a moderate to strong nuclear and cytoplasmic staining reaction.

  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CDKN2A/p16INK4a antibody [JC2] (ab267833), expandable thumbnail

    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CDKN2A/p16INK4a antibody [JC2] (ab267833)

    Formalin-fixed, parafin-embedded uterine cervix tissue stained for CDKN2A/p16INK4a using ab267833 at 1/50 dilution for 30 mins at room temperature. Antigen retrieval was performed using TEDTA buffer pH 8 and blue Hematoxylin was used as a counter stain. No staining reaction is seen in the squamous epithelial cell.

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Product protocols

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