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AB59717

Anti-CEACAM19 antibody [HY-8H10]

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(1 Publication)

Mouse Monoclonal CEACAM19 antibody. Carrier free. Suitable for Flow Cyt and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human CEACAM19.

View Alternative Names

CEAL1, UNQ2973/PRO7436, CEACAM19, Cell adhesion molecule CEACAM19, Carcinoembryonic antigen-like 1, Carcinoembryonic antigen-related cell adhesion molecule 19, CEA cell adhesion molecule 19

1 Images
Flow Cytometry - Anti-CEACAM19 antibody [HY-8H10] (AB59717)
  • Flow Cyt

Unknown

Flow Cytometry - Anti-CEACAM19 antibody [HY-8H10] (AB59717)

BOSC23 cells were transiently trans-fected with an expression vector encoding either CEACAM19 (red curve) or an irrelevant protein (control transfectant). Binding of ab59717 was detected with a PE conjugated secondary antibody. A positive signal was obtained only with CEACAM19 transfected cells.

Key facts

Host species

Mouse

Clonality

Monoclonal

Clone number

HY-8H10

Isotype

IgG1

Carrier free

Yes

Reacts with

Human

Applications

Flow Cyt

applications

Immunogen

Recombinant Full Length Protein corresponding to Human CEACAM19.

Q7Z692

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "1.2 µg for 10^6 Cells", "FlowCyt-species-notes": "<p><a href='/en-us/products/primary-antibodies/mouse-igg1-kappa-monoclonal-15-6e10a7-isotype-control-ab170190'>ab170190</a> - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.</p>" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein G
Storage buffer
pH: 7.2 Constituents: PBS
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

CEACAM19 short for Carcinoembryonic Antigen-related Cell Adhesion Molecule 19 is a protein with a molecular weight of approximately 38 kDa. CEACAM19 belongs to the CEACAM family which includes a range of cell adhesion molecules. It is predominantly expressed in epithelial tissues where it plays an important role in mediating intercellular interactions. Its presence is often noted in tissues like the gastrointestinal tract and lungs suggesting its involvement in maintaining the structural integrity of these tissues.
Biological function summary

CEACAM19 engages in cellular adhesion and communication processes critical for tissue organization. It is not typically associated as a part of larger protein complexes but operates individually. This protein is also important in mediating interactions between cells and the extracellular matrix which is essential for cell signaling and the maintenance of cellular environments. CEACAM proteins including CEACAM19 play roles in differentiation and proliferation in epithelial cells suggesting that this protein has implications in tissue development and homeostasis.

Pathways

Other CEACAM proteins are involved in immune response and cell signaling pathways but specific pathways involving CEACAM19 need more exploration. The CEACAM family including CEACAM19 is often linked to cell signaling and immunomodulatory processes. It might interact with other members of the CEACAM family such as CEACAM5 or CEACAM6 which are known to be involved in similar pathways suggesting a potential collaborative or regulatory role in epithelial tissue response to stimuli.

Abnormalities in CEACAM19 expression have been of interest in cancer studies particularly gastrointestinal and lung cancers. Alterations in its expression can affect tissue architecture potentially leading to tumorigenesis or aiding in metastasis. CEACAM19 may also have relevance in inflammatory disorders given its role in cell adhesion and tissue integrity indicating a connection to inflammation-related proteins such as CEACAM1 or CEACAM6 which are known to modulate inflammatory responses. Further studies are needed to elucidate the exact mechanisms of how CEACAM19 interacts within these diseases.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

See full target information CEACAM19
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

British journal of cancer 107:1745-53 PubMed23099808

2012

Carcinoembryonic antigen-related cell adhesion molecules as surrogate markers for EGFR inhibitor sensitivity in human lung adenocarcinoma.

Applications

Unspecified application

Species

Unspecified reactive species

M Kobayashi,Y Miki,M Ebina,K Abe,K Mori,S Narumi,T Suzuki,I Sato,M Maemondo,C Endo,A Inoue,H Kumamoto,T Kondo,H Yamada-Okabe,T Nukiwa,H Sasano
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Product promise

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