AB64873

Anti-Cell adhesion molecule 2 antibody

Name: Anti-Cell adhesion molecule 2 antibody (ab64873) | Abcam
Brand: Abcam Limited
SKU: AB64873
Price: 520 USD
Availability: InStock

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(9 Publications)

Rabbit Polyclonal Cell adhesion molecule 2 antibody. Suitable for WB and reacts with Human samples. Cited in 9 publications. Immunogen corresponding to Synthetic Peptide within Human CADM2.

View Alternative Names

IGSF4D, NECL3, CADM2, Cell adhesion molecule 2, Immunoglobulin superfamily member 4D, Nectin-like protein 3, Synaptic cell adhesion molecule 2, IgSF4D, NECL-3, SynCAM 2

1 Images

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Western blot - Anti-Cell adhesion molecule 2 antibody (AB64873)

All lanes:

Western blot - Anti-Cell adhesion molecule 2 antibody (ab64873) at 1/500 dilution

Lane 1:

Extracts from HepG2 cells at 10 µg

Lane 2:

Extracts from HepG2 cells at 10 µg with immunizing peptide

Predicted band size: 48 kDa

Observed band size: 48 kDa

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Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

Reacts with

Human

Applications

applications

Immunogen

Synthetic Peptide within Human CADM2. The exact immunogen used to generate this antibody is proprietary information.

Q8N3J6

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/1000", "WB-species-notes": "<p></p>" } } }

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Immunogen

Storage buffer

pH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine), 0.87% Sodium chloride

Shipped at conditions

Blue Ice

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Storage information

Stable for 12 months at -20°C

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Adhesion molecule that engages in homo- and heterophilic interactions with the other nectin-like family members, leading to cell aggregation. Important for synapse organization, providing regulated trans-synaptic adhesion. Preferentially binds to oligodendrocytes.. Isoform 5. (Microbial infection) Induces cell fusion in neuron infected by a neuropathogenic strain of measles.Interacts with measles hemagglutinin to trigger hyperfusogenic F-mediated membrane fusion and presumably transsynaptic cell-to-cell transmission of the virus.

See full target information CADM2

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Publications (9)

Recent publications for all applications. Explore the full list and refine your search

Signal transduction and targeted therapy 9:254 PubMed39327467

2024

Palmitoylation regulates myelination by modulating the ZDHHC3-Cadm4 axis in the central nervous system.

Applications

Unspecified application

Species

Unspecified reactive species

Yanli Chang,Jiangli Zhu,Xiaopeng Li,Yi Deng,Birou Lai,Yidan Ma,Jia Tong,Huicong Liu,Juanjuan Li,Chenyu Yang,Qiao Chen,Chengbiao Lu,Yinming Liang,Shiqian Qi,Xiaoning Wang,Eryan Kong

Open medicine (Warsaw, Poland) 17:1903-1914 PubMed36561840

2022

Long noncoding RNA WT1-AS regulates trophoblast proliferation, migration, and invasion via the microRNA-186-5p/CADM2 axis.

Applications

Unspecified application

Species

Unspecified reactive species

Qun Qiu,Juan Tan

Pathobiology : journal of immunopathology, molecular and cellular biology 89:233-244 PubMed35279660

2022

Long Non-Coding RNA HCG11 Inhibits Glioma Cells Proliferation and Migration through Decoying miR-590-3p and Up-Regulating CADM2.

Applications

Unspecified application

Species

Unspecified reactive species

Ma Jinyang,Lang Bojuan,Xue Lixin,Ding Wan,Tao Sun

Experimental and therapeutic medicine 23:16 PubMed34815768

2021

MicroRNA-25 promotes cell proliferation, migration and invasion in glioma by directly targeting cell adhesion molecule 2.

Applications

Unspecified application

Species

Unspecified reactive species

Gang Peng,Yi Liu,Chenxing Yang,Chenfu Shen

Cancer management and research 12:289-302 PubMed32021443

2020

Long Noncoding MAGI2-AS3 Suppresses Several Cellular Processes of Lung Squamous Cell Carcinoma Cells by Regulating miR-374a/b-5p/CADM2 Axis.

Applications

Unspecified application

Species

Unspecified reactive species

Jia He,Xiaoyun Zhou,Li Li,Zhijun Han

Oncology reports 41:2273-2280 PubMed30816549

2019

CADM2 inhibits human glioma proliferation, migration and invasion.

Applications

Unspecified application

Species

Unspecified reactive species

Nan Liu,Chen Yang,Wansheng Bai,Zhen Wang,Xin Wang,Mark Johnson,Wenshi Wang,Pengxing Zhang,Hongwei Yang,Hui Liu,Yingduan Cheng,Yanyang Tu

International journal of oncology 53:2615-2626 PubMed30320366

2018

Downregulation of microRNA‑182 inhibits cell viability, invasion and angiogenesis in retinoblastoma through inhibition of the PI3K/AKT pathway and CADM2 upregulation.

Applications

Unspecified application

Species

Unspecified reactive species

Yan-Xia Huang,Xin-Gang Nie,Guang-Da Li,Dong-Sheng Fan,Li-Li Song,Xin-Lin Zhang

International journal of molecular medicine 40:1851-1859 PubMed29039453

2017

MicroRNA-125a-3p is involved in early behavioral disorders in stroke-afflicted rats through the regulation of Cadm2.

Applications

Unspecified application

Species

Unspecified reactive species

Yuqing Liu,Yunjun Li,Zhenxing Ren,Wenwen Si,Yiwei Li,Gang Wei,Wenguang Zhao,Jianhong Zhou,Yage Tian,Dongfeng Chen

Proceedings of the National Academy of Sciences of 107:10250-5 PubMed20479255

2010

Synaptic cell adhesion molecule SynCAM 1 is a target for polysialylation in postnatal mouse brain.

Applications

ICC/IF

Species

Mouse

Sebastian P Galuska,Manuela Rollenhagen,Moritz Kaup,Katinka Eggers,Imke Oltmann-Norden,Miriam Schiff,Maike Hartmann,Birgit Weinhold,Herbert Hildebrandt,Rudolf Geyer,Martina Mühlenhoff,Hildegard Geyer

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

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Anti-Cell adhesion molecule 2 antibody

Western blot - Anti-Cell adhesion molecule 2 antibody (AB64873)

Key facts

Host species

Clonality

Isotype

Carrier free

Reacts with

Applications

Immunogen

Reactivity data

Properties and storage information

Form

Purification technique

Storage buffer

Shipped at conditions

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Storage information

Product protocols

Target data

Publications (9)

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Primary Antibodies

Primary Antibodies

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Product promise