AB88521

Anti-CHRAC-17 antibody

Name: Anti-CHRAC-17 antibody (ab88521) | Abcam
Brand: Abcam Limited
SKU: AB88521
Price: 545 USD
Availability: InStock

Be the first to review this product! Submit a review

(1 Publication)

Mouse Polyclonal CHRAC-17 antibody. Carrier free. Suitable for WB, ICC/IF and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human POLE3.

View Alternative Names

CHRAC17, POLE3, DNA polymerase epsilon subunit 3, Arsenic-transactivated protein, Chromatin accessibility complex 17 kDa protein, DNA polymerase II subunit 3, DNA polymerase epsilon subunit p17, AsTP, CHRAC-17, HuCHRAC17

3 Images

Immunocytochemistry/ Immunofluorescence - Anti-CHRAC-17 antibody (AB88521)

ICC/IF

Unknown

Immunocytochemistry/ Immunofluorescence - Anti-CHRAC-17 antibody (AB88521)

ab88521, at 10 μg/ml, staining CHRAC-17 in HeLa cells by Immunofluorescence.

Unknown

Western blot - Anti-CHRAC-17 antibody (AB88521)

All lanes:

Western blot - Anti-CHRAC-17 antibody (ab88521) at 1 µg/mL

Lane 1:

CHRAC-17 transfected HEK-293T cell lysate at 25 µg

Lane 2:

Non-transfected HEK-293T cell lysate at 25 µg

Predicted band size: 16 kDa

Observed band size: 17 kDa

false

Unknown

Western blot - Anti-CHRAC-17 antibody (AB88521)

All lanes:

Western blot - Anti-CHRAC-17 antibody (ab88521) at 1 µg/mL

All lanes:

Human liver tissue lysate at 50 µg

Predicted band size: 16 kDa

Observed band size: 20 kDa

false

Key facts

Host species

Mouse

Clonality

Polyclonal

Isotype

IgG

Carrier free

Yes

Reacts with

Human

Applications

WB, ICC/IF

applications

Immunogen

Recombinant Full Length Protein corresponding to Human POLE3.

Q9NRF9

style

left-column

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1 µg/mL", "WB-species-notes": "<p></p>", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "10 µg/mL", "ICCIF-species-notes": "<p></p>" } } }

style

left-column

style

left-column

Properties and storage information

Form

Liquid

Purification technique

Affinity purification Protein A

Storage buffer

pH: 7.4 Constituents: PBS

Shipped at conditions

Blue Ice

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

style

left-column

style

left-column

style

left-column

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

style

left-column

Target data

Accessory component of the DNA polymerase epsilon complex (PubMed : 10801849). Participates in DNA repair and in chromosomal DNA replication (By similarity). Forms a complex with CHRAC1 and binds naked DNA, which is then incorporated into chromatin, aided by the nucleosome-remodeling activity of ISWI/SNF2H and ACF1 (PubMed : 10801849). Does not enhance nucleosome sliding activity of the ACF-5 ISWI chromatin remodeling complex (PubMed : 14759371).

See full target information POLE3

style

left-column

Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Frontiers in pharmacology 16:1518481 PubMed39931687

2025

The gut-kidney axis is regulated by astragaloside IV to inhibit cyclosporine A-induced nephrotoxicity.

Applications

Unspecified application

Species

Unspecified reactive species

Cong Han,Ran-Ran Gao,Le Zhou,Wei Li

View all publications

style

left-column

style

left-column

style

right-column

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-CHRAC-17 antibody

Immunocytochemistry/ Immunofluorescence - Anti-CHRAC-17 antibody (AB88521)

Western blot - Anti-CHRAC-17 antibody (AB88521)

Western blot - Anti-CHRAC-17 antibody (AB88521)

Key facts

Host species

Clonality

Isotype

Carrier free

Reacts with

Applications

Immunogen

Reactivity data

Properties and storage information

Form

Purification technique

Storage buffer

Shipped at conditions

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Aliquoting information

Storage information

Product protocols

Target data

Publications (1)

Alternative Products

Primary Antibodies

Primary Antibodies

Complementary Products

Cell Lines & Lysates

Primary Antibodies

Cell Lines & Lysates

Primary Antibodies

Product promise