AB154904

Anti-CIAPIN1 antibody

Name: Anti-CIAPIN1 antibody (ab154904) | Abcam
Brand: Abcam Limited
SKU: AB154904
Price: 520 USD
Availability: InStock

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(9 Publications)

Rabbit Polyclonal CIAPIN1 antibody. Suitable for WB, IHC-P and reacts with Mouse, Human samples. Cited in 9 publications. Immunogen corresponding to Recombinant Fragment Protein within Human CIAPIN1 aa 1 to C-terminus.

View Alternative Names

CUA001, PRO0915, CIAPIN1, Anamorsin, Cytokine-induced apoptosis inhibitor 1, Fe-S cluster assembly protein DRE2 homolog

3 Images

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CIAPIN1 antibody (AB154904)

IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CIAPIN1 antibody (AB154904)

Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human SkHep1 xenograft tissue labeling CIAPIN1 with ab154904 at 1/500 dilution.

Unknown

Western blot - Anti-CIAPIN1 antibody (AB154904)

10% SDS PAGE

All lanes:

Western blot - Anti-CIAPIN1 antibody (ab154904) at 1/1000 dilution

Lane 1:

Jurkat whole cell lysate at 30 µg

Lane 2:

Raji whole cell lysate at 30 µg

Lane 3:

K562 whole cell lysate at 30 µg

Lane 4:

THP1 whole cell lysate at 30 µg

Lane 5:

HL60 whole cell lysate at 30 µg

Lane 6:

NCI-H929 whole cell lysate at 30 µg

Predicted band size: 34 kDa

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Western blot - Anti-CIAPIN1 antibody (AB154904)

10% SDS PAGE

All lanes:

Western blot - Anti-CIAPIN1 antibody (ab154904) at 1/3000 dilution

Lane 1:

NIH 3T3 whole cell lysate at 30 µg

Lane 2:

JC whole cell lysate at 30 µg

Lane 3:

BCL1 whole cell lysate at 30 µg

Predicted band size: 34 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

Reacts with

Mouse, Human

Applications

IHC-P, WB

applications

Immunogen

Recombinant Fragment Protein within Human CIAPIN1 aa 1 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.

Q6FI81

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/3000", "WB-species-notes": "", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/100 - 1/1000", "IHCP-species-notes": "" }, "Mouse": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/3000", "WB-species-notes": "", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" } } }

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Immunogen

Storage buffer

pH: 7 Preservative: 0.01% Thimerosal (merthiolate) Constituents: PBS, 20% Glycerol (glycerin, glycerine)

Shipped at conditions

Blue Ice

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex NUBP1-NUBP2. Electrons are transferred to CIAPIN1 from NADPH via the FAD- and FMN-containing protein NDOR1 (PubMed : 23596212). NDOR1-CIAPIN1 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit (By similarity). Has anti-apoptotic effects in the cell. Involved in negative control of cell death upon cytokine withdrawal. Promotes development of hematopoietic cells (By similarity).

See full target information CIAPIN1

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Publications (9)

Recent publications for all applications. Explore the full list and refine your search

Scientific reports 15:27739 PubMed40730854

2025

CIAPIN1 promotes survival, proliferation, migration and glycolysis of endometrial cancer cells through PI3K/Akt pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Huanmei Sun,Juan Shao,Yingchun Duan,Jiashi Gu

Physiological reports 13:e70360 PubMed40338178

2025

CIAPIN1 promotes proliferation and migration of PDGF-BB-activated airway smooth muscle cells via the PI3K/AKT and JAK2/STAT3 signaling pathways.

Applications

Unspecified application

Species

Unspecified reactive species

Ling Zhu,Jin Zhou,Yunfan Gu,Yongtian Xu,Yanfang Guo

BMC nephrology 26:201 PubMed40259237

2025

CIAPIN1 attenuates ferroptosis via regulating PI3K/AKT pathway in LPS-induced podocytes.

Applications

Unspecified application

Species

Unspecified reactive species

Ziqing Zhang,Jinmiao Ma,Minyu Shi,Jingcong Huang,Zhenyu Xu

Iranian journal of basic medical sciences 28:72-79 PubMed39877633

2025

Lysyl oxidase-like 2 promotes the survival, migration, and ferroptosis of endometrial cancer cells by activating the phosphoinositide 3-kinase/protein kinase B pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Jiashi Gu,Huanmei Sun,Juan Shao,Hu Zhang,Zhanpeng Zhu,Dongqin Ma,Yingchun Duan

Scientific reports 14:20794 PubMed39242716

2024

Downregulation of CIAPIN1 regulates the proliferation, migration and glycolysis of breast cancer cells via inhibition of STAT3 pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Hao Yuan,Ming Zhong,Jie Liu,Shuya Tang,Hongbo Zhu,Qingping Wei,Bingbing Pu,Yongping Li

Pathology oncology research : POR 25:1181-1190 PubMed30637589

2019

MiRNA-195-5p Functions as a Tumor Suppressor and a Predictive of Poor Prognosis in Non-small Cell Lung Cancer by Directly Targeting CIAPIN1.

Applications

Unspecified application

Species

Unspecified reactive species

Jing Zheng,Tingting Xu,Feng Chen,Ying Zhang

Molecules (Basel, Switzerland) 22: PubMed28858244

2017

Andrographolide Suppresses MV4-11 Cell Proliferation through the Inhibition of FLT3 Signaling, Fatty Acid Synthesis and Cellular Iron Uptake.

Applications

Unspecified application

Species

Unspecified reactive species

Xiao Chen,Jianbin Zhang,Lixia Yuan,Yifei Lay,Yin Kwan Wong,Teck Kwang Lim,Chye Sun Ong,Qingsong Lin,Jigang Wang,Zichun Hua

Oncology letters 13:4695-4700 PubMed28588724

2017

Upregulation of microRNA-143 reverses drug resistance in human breast cancer cells via inhibition of cytokine-induced apoptosis inhibitor 1.

Applications

Species

Unspecified reactive species

Jing-Hao Wang,Xiu-Wen Wang,Di Qu,Ji-Wen Sun,Fei-Xiao Guo,Dan Lu

Molecular medicine reports 12:2056-62 PubMed25901506

2015

Cytokine-induced apoptosis inhibitor 1 inhibits the growth and proliferation of multiple myeloma.

Applications

Unspecified application

Species

Unspecified reactive species

Xiaobo Wang,Jingxuan Pan,Juan Li

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

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Anti-CIAPIN1 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CIAPIN1 antibody (AB154904)

Western blot - Anti-CIAPIN1 antibody (AB154904)

Western blot - Anti-CIAPIN1 antibody (AB154904)

Key facts

Host species

Clonality

Isotype

Carrier free

Reacts with

Applications

Immunogen

Reactivity data

Properties and storage information

Form

Purification technique

Storage buffer

Shipped at conditions

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Aliquoting information

Storage information

Product protocols

Target data

Publications (9)

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