Mouse Polyclonal CIKS/ACT1 antibody. Suitable for WB and reacts with Human samples. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human TRAF3IP2.
pH: 7.4
Constituents: 100% PBS
WB | |
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Human | Tested |
Rat | Predicted |
Orangutan | Predicted |
Species | Dilution info | Notes |
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Species Human | Dilution info 1 µg/mL | Notes - |
Species | Dilution info | Notes |
---|---|---|
Species Rat, Orangutan | Dilution info - | Notes - |
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E3 ubiquitin ligase that catalyzes 'Lys-63'-linked polyubiquitination of target protein, enhancing protein-protein interaction and cell signaling (PubMed:19825828). Transfers ubiquitin from E2 ubiquitin-conjugating enzyme UBE2V1-UBE2N to substrate protein (PubMed:19825828). Essential adapter molecule in IL17A-mediated signaling (PubMed:19825828, PubMed:24120361). Upon IL17A stimulation, interacts with IL17RA and IL17RC receptor chains through SEFIR domains and catalyzes 'Lys-63'-linked polyubiquitination of TRAF6, leading to TRAF6-mediated activation of NF-kappa-B and MAPkinase pathways (PubMed:19825828).
C6orf2, C6orf4, C6orf5, C6orf6, TRAF3IP2, E3 ubiquitin ligase TRAF3IP2, Adapter protein CIKS, Connection to IKK and SAPK/JNK, E3 ubiquitin-protein ligase CIKS, Nuclear factor NF-kappa-B activator 1, TRAF3-interacting protein 2, ACT1
Mouse Polyclonal CIKS/ACT1 antibody. Suitable for WB and reacts with Human samples. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human TRAF3IP2.
pH: 7.4
Constituents: 100% PBS
We have tested this species and application combination and it works. It is covered by our product promise.
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
We do not recommend this combination. It is not covered by our product promise.
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All lanes: Western blot - Anti-CIKS/ACT1 antibody (ab172509) at 1 µg/mL
Lane 1: CIKS/ACT1 transfected 293T lysate at 15 µL
Lane 2: Non-transfected 293T lysate at 15 µL
Developed using the ECL technique.
Predicted band size: 65 kDa
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