AB192881

Anti-CILP antibody [EPR16303]

RabMAb
Recombinant
What is this?

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(6 Publications)

Rabbit Recombinant Monoclonal CILP antibody. Suitable for WB and reacts with Human samples. Cited in 6 publications.

View Alternative Names

UNQ602/PRO1188, CILP, Cartilage intermediate layer protein 1, CILP-1, Cartilage intermediate-layer protein

1 Images

Supplier Data

Western blot - Anti-CILP antibody [EPR16303] (AB192881)

All lanes:

Western blot - Anti-CILP antibody [EPR16303] (ab192881) at 1/5000 dilution

All lanes:

Human cartilage lysate at 10 µg

Secondary

All lanes:

Anti-Rabbit IgG (HRP), specific to the non-reduced form of IgG at 1/1000 dilution

Predicted band size: 133 kDa

Observed band size: 90 kDa

false

Key facts

Host species

Rabbit

Clonality

Monoclonal

Clone number

EPR16303

Isotype

IgG

Carrier free

Reacts with

Human

Applications

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/10000", "WB-species-notes": "<p></p>" } } }

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Product details

Patented technology
Our RabMAb^® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb^® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production

For more information, read more on recombinant antibodies.

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Protein A

Storage buffer

pH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA

Shipped at conditions

Blue Ice

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Probably plays a role in cartilage scaffolding. May act by antagonizing TGF-beta1 (TGFB1) and IGF1 functions. Has the ability to suppress IGF1-induced proliferation and sulfated proteoglycan synthesis, and inhibits ligand-induced IGF1R autophosphorylation. May inhibit TGFB1-mediated induction of cartilage matrix genes via its interaction with TGFB1. Overexpression may lead to impair chondrocyte growth and matrix repair and indirectly promote inorganic pyrophosphate (PPi) supersaturation in aging and osteoarthritis cartilage.

See full target information CILP

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Publications (6)

Recent publications for all applications. Explore the full list and refine your search

Cell death & disease 16:371 PubMed40346063

2025

CILP1 interacting with YBX1 promotes hypertrophic scar formation by suppressing PPARs transcription.

Applications

Unspecified application

Species

Unspecified reactive species

Jianzhang Wang,Juan Du,Yajuan Song,Xiaoying Tan,Junzheng Wu,Tong Wang,Yi Shi,Xingbo Xu,Zhou Yu,Baoqiang Song

British journal of cancer 128:2116-2125 PubMed37016102

2023

Development of the semi-dry dot-blot method for intraoperative detecting micropapillary component in lung adenocarcinoma based on proteomics analysis.

Applications

Unspecified application

Species

Unspecified reactive species

Long Xu,Hang Su,Shengnan Zhao,Haojie Si,Huikang Xie,Yijiu Ren,Jiani Gao,Fang Wang,Xiaofeng Xie,Chenyang Dai,Chunyan Wu,Deping Zhao,Chang Chen

Technology in cancer research & treatment 21:15330338221117003 PubMed35899307

2022

Weighted Correlation Network Analysis of Cancer Stem Cell-Related Prognostic Biomarkers in Esophageal Squamous Cell Carcinoma.

Applications

Unspecified application

Species

Unspecified reactive species

Mengnan Zhao,Xing Jin,Zhencong Chen,Huan Zhang,Cheng Zhan,Hao Wang,Qun Wang

Frontiers in genetics 13:862264 PubMed35711946

2022

CILP, a Putative Gene Associated With Immune Infiltration in Breast Cancer Brain Metastases.

Applications

Unspecified application

Species

Unspecified reactive species

Xiaolin Sun,Ning Yang,Xingguo Zhou,Honghai Dai,Qiang Li,Alei Feng,Gongwen Xu,Yingchao Liu,Linzong Xu,Zhanyu Zhang,Zhe Yang,Xiaomei Li

Journal of orthopaedic surgery and research 16:440 PubMed34233701

2021

MiR-330-5p inhibits intervertebral disk degeneration via targeting CILP.

Applications

Unspecified application

Species

Unspecified reactive species

Shangzhi Li,Jinwei Liu,Liang Chen

Molecular medicine reports 17:6130-6137 PubMed29436660

2018

Cartilage intermediate layer protein is regulated by mechanical stress and affects extracellular matrix synthesis.

Applications

Unspecified application

Species

Unspecified reactive species

Jinyue He,Chencheng Feng,Jing Sun,Kang Lu,Tongwei Chu,Yue Zhou,Yong Pan

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-CILP antibody [EPR16303]

Western blot - Anti-CILP antibody [EPR16303] (AB192881)

Key facts

Host species

Clonality

Clone number

Isotype

Carrier free

Reacts with

Applications

Immunogen

Reactivity data

Product details

Properties and storage information

Form

Purification technique

Storage buffer

Shipped at conditions

Appropriate short-term storage duration

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Aliquoting information

Storage information

Product protocols

Target data

Publications (6)

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Secondary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Product promise