AB233711

Anti-CIRP antibody [6E12D5]

Name: Anti-CIRP antibody [6E12D5] (ab233711) | Abcam
Brand: Abcam Limited
SKU: AB233711

Be the first to review this product! Submit a review

(1 Publication)

Mouse Monoclonal CIRP antibody. Suitable for WB, IHC-P and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human CIRBP aa 1-100.

View Alternative Names

A18HNRNP, CIRP, CIRBP, Cold-inducible RNA-binding protein, A18 hnRNP, Glycine-rich RNA-binding protein CIRP

4 Images

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CIRP antibody [6E12D5] (AB233711)

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CIRP antibody [6E12D5] (AB233711)

Paraffin-embedded human colon cancer tissue stained for CIRP using ab233711 at 1/200 dilution in immunohistochemical analysis. DAB staining.

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CIRP antibody [6E12D5] (AB233711)

Paraffin-embedded human bladder cancer tissue stained for CIRP using ab233711 at 1/200 dilution in immunohistochemical analysis. DAB staining.

Supplier Data

Western blot - Anti-CIRP antibody [6E12D5] (AB233711)

All lanes:

Western blot - Anti-CIRP antibody [6E12D5] (ab233711) at 1/500 dilution

All lanes:

Recombinant human CIRP (aa1-90) protein

Predicted band size: 18 kDa

true

Supplier Data

Western blot - Anti-CIRP antibody [6E12D5] (AB233711)

All lanes:

Western blot - Anti-CIRP antibody [6E12D5] (ab233711) at 1/500 dilution

Lane 1:

Untransfected HEK-293 (human epithelial cell line from embryonic kidney) cell lysate

Lane 2:

Human CIRP (aa1-90)-IgG-Fc-transfected HEK-293 cell lysate

Predicted band size: 18 kDa

true

Key facts

Host species

Mouse

Clonality

Monoclonal

Clone number

6E12D5

Isotype

IgG1

Carrier free

Reacts with

Human

Applications

WB, IHC-P

applications

Immunogen

Recombinant Fragment Protein within Human CIRBP aa 1-100. The exact immunogen used to generate this antibody is proprietary information.

Q14011

style

left-column

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/2000", "WB-species-notes": "<p></p>", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/200 - 1/1000", "IHCP-species-notes": "<p></p>" } } }

style

left-column

style

left-column

Properties and storage information

Form

Liquid

Purification technique

Affinity purification Protein G

Purification notes

Purified from tissue culture supernatant.

Storage buffer

Preservative: 0.05% Sodium azide Constituents: PBS

Shipped at conditions

Blue Ice

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

style

left-column

style

left-column

style

left-column

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

style

left-column

Target data

Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. Acts as a translational activator. Seems to play an essential role in cold-induced suppression of cell proliferation. Binds specifically to the 3'-untranslated regions (3'-UTRs) of stress-responsive transcripts RPA2 and TXN. Acts as a translational repressor (By similarity). Promotes assembly of stress granules (SGs), when overexpressed.

See full target information CIRBP

style

left-column

Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Journal of neuroinflammation 20:285 PubMed38037097

2023

Single-cell RNA sequencing unveils Lrg1's role in cerebral ischemia‒reperfusion injury by modulating various cells.

Applications

Unspecified application

Species

Unspecified reactive species

Zhaohui Ruan,Guosheng Cao,Yisong Qian,Longsheng Fu,Jinfang Hu,Tiantian Xu,Yaoqi Wu,Yanni Lv

View all publications

style

left-column

style

left-column

style

right-column

Alternative Products

Primary Antibodies

AB106230

Anti-CIRP antibody

Western blot - Anti-CIRP antibody (AB106230)

Primary Antibodies

AB191885

Anti-CIRP antibody [EPR18783]

RabMAb|Recombinant|KO Validated

Immunocytochemistry/ Immunofluorescence - Anti-CIRP antibody [EPR18783] (AB191885)

Primary Antibodies

AB238946

Anti-CIRP antibody [EPR18783] - BSA and Azide free

RabMAb|Recombinant|KO Validated

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CIRP antibody [EPR18783] - BSA and Azide free (AB238946)

Primary Antibodies

AB166775

Anti-CIRP antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CIRP antibody (AB166775)

Complementary Products

Primary Antibodies

AB134946

Anti-RBM3 antibody [EPR6061(2)]

BOND RX™ Validated|KO Validated|RabMAb|Recombinant

Flow Cytometry (Intracellular) - Anti-RBM3 antibody [EPR6061(2)] (AB134946)

Secondary Antibodies

AB150077

Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488)

Immunocytochemistry/ Immunofluorescence - Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (AB150077)

Primary Antibodies

AB15580

Anti-Ki67 antibody

BOND RX™ Validated|KO Validated

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Ki67 antibody (AB15580)

Primary Antibodies

AB177487

Anti-NeuN antibody [EPR12763] - Neuronal Marker

Immunohistochemistry (Frozen sections) - Anti-NeuN antibody [EPR12763] - Neuronal Marker (AB177487)

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com