JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB192383

Anti-CISH/CIS antibody

Be the first to review this product! Submit a review

|

(1 Publication)

Rabbit Polyclonal CISH/CIS antibody. Suitable for WB and reacts with Human, Mouse, Rat samples. Cited in 1 publication. Immunogen corresponding to Synthetic Peptide within Human CISH.

View Alternative Names

G18, CISH, Cytokine-inducible SH2-containing protein, CIS, CIS-1, Protein G18, Suppressor of cytokine signaling, SOCS

1 Images
Western blot - Anti-CISH/CIS antibody (AB192383)
  • WB

Supplier Data

Western blot - Anti-CISH/CIS antibody (AB192383)

All lanes:

Western blot - Anti-CISH/CIS antibody (ab192383)

Lane 1:

MCF-7 whole cell lysate

Lane 2:

Mouse brain lysate

Lane 3:

PC12 whole cell lysate

Predicted band size: 29 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Mouse, Rat, Human

Applications

WB

applications

Immunogen

Synthetic Peptide within Human CISH. The exact immunogen used to generate this antibody is proprietary information.

Q9NSE2

style
left-column

Alternative Products

Primary Antibodies

AB191447

Anti-CISH/CIS antibody - C-terminal

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CISH/CIS antibody - C-terminal (AB191447)

  • 0
  • 0
Primary Antibodies

AB88383

Anti-CISH/CIS antibody

Immunocytochemistry/ Immunofluorescence - Anti-CISH/CIS antibody (AB88383)

  • 0
  • 0

Complementary Products

Secondary Antibodies

AB150077

Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488)

Immunocytochemistry/ Immunofluorescence - Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (AB150077)

  • 5
  • 20
Primary Antibodies

AB16030

Anti-SOCS3 antibody

Western blot - Anti-SOCS3 antibody (AB16030)

  • 4
  • 31
Proteins & Peptides

AB117057

Recombinant Human CISH/CIS protein

SDS-PAGE - Recombinant Human CISH/CIS protein (AB117057)

  • 0
  • 0
Primary Antibodies

AB183218

Anti-TNF alpha antibody [EPR19147]

KO Validated|RabMAb|Recombinant|Lab Essentials

Immunocytochemistry/ Immunofluorescence - Anti-TNF alpha antibody [EPR19147] (AB183218)

  • 5
  • 1
style
left-column

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "", "WB-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "", "WB-species-notes": "<p></p>" }, "Rat": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "", "WB-species-notes": "<p></p>" } } }
style
left-column
style
left-column

Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Purification notes
ab192383 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage buffer
Preservative: 0.1% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine)
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
style
left-column
style
left-column
style
left-column

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
style
left-column

Target data

SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. CIS is involved in the negative regulation of cytokines that signal through the JAK-STAT5 pathway such as erythropoietin, prolactin and interleukin 3 (IL3) receptor. Inhibits STAT5 trans-activation by suppressing its tyrosine phosphorylation. May be a substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity).
See full target information CISH
style
left-column

Publications (1)

Recent publications for all applications. Explore the full list and refine your search

BMC medical genomics 18:38 PubMed40001159

2025

Targeting RECQL4 in hepatocellular carcinoma: from prognosis to therapeutic potential.

Applications

Unspecified application

Species

Unspecified reactive species

Yingchen Li,Linan Yin,Bowen Liu,Yan Liu,Dongfeng He,Xuesong Liu,Ruibao Liu
View all publications
style
left-column
style
left-column
style
right-column

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com