Anti-Claudin 5 antibody [EPR7583] ab131259 is a rabbit monoclonal antibody that is used in Claudin 5 western blotting, IHC and immunofluorescence. Suitable for human samples.
- Recombinant format for unrivaled batch-batch consistency: no need for same-lot requests
- Specificity and sensitivity confirmed in IHC with multi-tissue microarray (TMA) validation
- Antibody clone EPR7583 is cited in over 110 publications
Images
![Western blot - Anti-Claudin 5 antibody [EPR7583] (AB131259), expandable thumbnail](https://content.abcam.com/products/images/claudin-5-antibody-epr7583-ab131259--western-blot-img105262.jpg/_jcr_content/renditions/webp-475.webp "Western blot - Anti-Claudin 5 antibody [EPR7583] (AB131259)")
![Western blot - Anti-Claudin 5 antibody [EPR7583] (AB131259), expandable thumbnail](https://content.abcam.com/products/images/claudin-5-antibody-epr7583-ab131259--western-blot-img161195.jpg/_jcr_content/renditions/webp-475.webp "Western blot - Anti-Claudin 5 antibody [EPR7583] (AB131259)")
![Western blot - Anti-Claudin 5 antibody [EPR7583] (AB131259), expandable thumbnail](https://content.abcam.com/products/images/claudin-5-antibody-epr7583-ab131259--western-blot-img25232.jpg/_jcr_content/renditions/webp-475.webp "Western blot - Anti-Claudin 5 antibody [EPR7583] (AB131259)")
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Claudin 5 antibody [EPR7583] (AB131259), expandable thumbnail](https://content.abcam.com/products/images/claudin-5-antibody-epr7583-ab131259--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img127875.jpg/_jcr_content/renditions/webp-475.webp "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Claudin 5 antibody [EPR7583] (AB131259)")
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Claudin 5 antibody [EPR7583] (AB131259), expandable thumbnail](https://content.abcam.com/products/images/claudin-5-antibody-epr7583-ab131259--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img74301.jpg/_jcr_content/renditions/webp-475.webp "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Claudin 5 antibody [EPR7583] (AB131259)")
Publications
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- Alzheimer's research & therapy 15:1532023Is later-life depression a risk factor for Alzheimer's disease or a prodromal symptom: a study using post-mortem human brain tissue?Applications:Unspecified applicationReactive species:Unspecified reactive speciesLindsey I Sinclair,Asher Mohr,Mizuki Morisaki,Martin Edmondson,Selina Chan,A Bone-Connaughton,Gustavo Turecki,Seth LovePubMed 37700368
- Frontiers in immunology 14:11723342023Pterostilbene attenuates microglial inflammation and brain injury after intracerebral hemorrhage in an OPA1-dependent manner.Applications:Unspecified applicationReactive species:Unspecified reactive speciesYang Wu,Qing Hu,Xiaoliang Wang,Hongbo Cheng,Jiegang Yu,Yang Li,Jianing Luo,Qingjiu Zhang,Jianliang Wu,Gengshen ZhangPubMed 37614235
- Archives of pharmacal research 46:564-5722023Paritaprevir ameliorates experimental acute lung injury in vitro and in vivo.Applications:Unspecified applicationReactive species:Unspecified reactive speciesRui Ren,Xin Wang,Zehui Xu,Wanglin JiangPubMed 37306915
- Aging 15:3715-37372023Plasmon-activated water as a therapeutic strategy in Alzheimer's disease by altering gut microbiota.Applications:Unspecified applicationReactive species:Unspecified reactive speciesChia-Hsiung Cheng,Yu-Chuan Liu,Yu-Chen S H Yang,Kun-Ju Lin,Dean Wu,Yun-Ru Liu,Chun-Chao Chang,Chien-Tai Hong,Chaur-Jong HuPubMed 37166426
- Scientific reports 13:52142023Medial prefrontal cortex oxytocin mitigates epilepsy and cognitive impairments induced by traumatic brain injury through reducing neuroinflammation in mice.Applications:Unspecified applicationReactive species:Unspecified reactive speciesWen Chen,Xiaoxiao Man,Yu Zhang,Guangyan Yao,Jing ChenPubMed 36997619
- Cancers 15:2023Ceramide Synthase 1 Inhibits Brain Metastasis of Non-Small Cell Lung Cancer by Interacting with USP14 and Downregulating the PI3K/AKT/mTOR Signaling Pathway.Applications:Unspecified applicationReactive species:Unspecified reactive speciesYiquan Xu,Junfan Pan,Ying Lin,Yun Wu,Yusheng Chen,Hongru LiPubMed 37046655
- Regenerative therapy 22:192-2022023Usefulness of a humanized tricellular static transwell blood-brain barrier model as a microphysiological system for drug development applications. - A case study based on the benchmark evaluations of blood-brain barrier microphysiological system.Applications:Unspecified applicationReactive species:Unspecified reactive speciesKimiko Nakayama-Kitamura,Yukari Shigemoto-Mogami,Hiroko Toyoda,Ikue Mihara,Hiroyuki Moriguchi,Hitoshi Naraoka,Tomomi Furihata,Seiichi Ishida,Kaoru SatoPubMed 36891355
- International journal of molecular sciences 24:2023YTHDF1 Attenuates TBI-Induced Brain-Gut Axis Dysfunction in Mice.Applications:Unspecified applicationReactive species:Unspecified reactive speciesPeizan Huang,Min Liu,Jing Zhang,Xiang Zhong,Chunlong ZhongPubMed 36835655
- Oxidative medicine and cellular longevity 2023:78577602023P7C3-A20 Attenuates Microglial Inflammation and Brain Injury after ICH through Activating the NAD/Sirt3 Pathway.Applications:Unspecified applicationReactive species:Unspecified reactive speciesYang Wu,Qing Hu,Xun Wu,Ya-Ning Cai,Yun-Ze Zhang,Ying-Xi Wu,Gang Zhu,Jia-Ning Luo,Hong-Bo Cheng,Jie-Gang Yu,Xiao-Liang Wang,Li Gao,Guo-Dong GaoPubMed 36819779
- GeroScience 45:1015-10312022Liver alterations and detection of SARS-CoV-2 RNA and proteins in COVID-19 autopsies.Applications:Unspecified applicationReactive species:Unspecified reactive speciesAdrián Pesti,Krisztina Danics,Tibor Glasz,Tibor Várkonyi,Tamás Barbai,Andrea Reszegi,Ilona Kovalszky,István Vályi-Nagy,Deján Dobi,Gábor Lotz,Zsuzsa Schaff,András KissPubMed 36527584
Key facts
- Isotype
IgG
- Host species
Rabbit
- Storage buffer
pH: 7.2 - 7.4
Preservative: 0.01% Sodium azide
Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA- Form
Liquid
- Clonality
Monoclonal
Immunogen
- The exact immunogen used to generate this antibody is proprietary information.
Reactivity data
Select an application| IHC-P | WB | ICC/IF | IHC-Fr | |
|---|---|---|---|---|
| Human | Tested | Tested | Tested | Not recommended |
| Mouse | Not recommended | Not recommended | Not recommended | Not recommended |
IHC-P
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info 1/100 - 1/1000 | Notes Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
Not recommendedNot recommended
| Species | Dilution info | Notes |
|---|---|---|
Species Mouse | Dilution info - | Notes - |
WB
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info 1/1000 - 1/10000 | Notes ab131259 failed to detect target band in mouse brain tissue. This antibody failed to get signal in cell lines when performing western blot, so we do not recommend to use it when testing cell lines in westen blot. |
Not recommendedNot recommended
| Species | Dilution info | Notes |
|---|---|---|
Species Mouse | Dilution info - | Notes - |
ICC/IF
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info 0.008 µg/mL | Notes - |
Not recommendedNot recommended
| Species | Dilution info | Notes |
|---|---|---|
Species Mouse | Dilution info - | Notes - |
IHC-Fr
Not recommendedNot recommended
| Species | Dilution info | Notes |
|---|---|---|
Species Mouse, Human | Dilution info - | Notes - |
Associated Products
Select an associated product type
1 product for Alternative Product
Target data
Function
Plays a major role in tight junction-specific obliteration of the intercellular space.
Alternative names
Claudin-5, Transmembrane protein deleted in VCFS, TMDVCF, TMVCF, AWAL, CLDN5
Recommended products
Anti-Claudin 5 antibody [EPR7583] ab131259 is a rabbit monoclonal antibody that is used in Claudin 5 western blotting, IHC and immunofluorescence. Suitable for human samples.
- Recombinant format for unrivaled batch-batch consistency: no need for same-lot requests
- Specificity and sensitivity confirmed in IHC with multi-tissue microarray (TMA) validation
- Antibody clone EPR7583 is cited in over 110 publications
Key facts
- Isotype
IgG
- Host species
Rabbit
- Storage buffer
pH: 7.2 - 7.4
Preservative: 0.01% Sodium azide
Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA- Form
Liquid
- Clonality
Monoclonal
- Immunogen
- The exact immunogen used to generate this antibody is proprietary information.
- Clone number
EPR7583
- Purification technique
Affinity purification Protein A
- Specificity
ab131259 failed to detect target band in mouse brain tissue. This antibody is unsuitable to be used in IHC on mouse tissues.
This antibody failed to get signal in cell lines when performing western blot, so we do not recommend to use it when testing cell lines in westen blot.
- Concentration
Storage
- Shipped at conditions
Blue Ice
- Appropriate short-term storage duration
1-2 weeks
- Appropriate short-term storage conditions
+4°C
- Appropriate long-term storage conditions
-20°C
- Aliquoting information
Upon delivery aliquot
- Storage information
Stable for 12 months at -20°C
Notes
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free batch production
For more information, read more on recombinant antibodies.
Rat: We have preliminary internal testing data to indicate this antibody may not react with this species. Please contact us for more information.
Supplementary info
This supplementary information is collated from multiple sources and compiled automatically.
- Activity summary
Claudin 5 also known as CLDN5 is an integral component of tight junction strands within endothelial and epithelial cells. This protein possesses a molecular weight of approximately 23 kDa. It prominently expresses in the vascular endothelial cells of the blood-brain barrier and other blood-tissue barriers. Claudin 5 plays a mechanical role in forming selectively permeable paracellular barriers that regulate the movement of molecules and ions between cells. This function is essential in preserving the tissue-specific environment.
- Biological function summary
Claudin 5 serves as an important element in maintaining the integrity of the blood-brain barrier by creating a selective permeability. It operates as part of a larger tight junction complex interacting mainly with other claudin proteins and proteins such as occludin and ZO-1. These interactions ensure the structural and functional integrity of the cell junctions which helps stabilize the barrier properties against various physiological and pathological insults.
- Pathways
Claudin 5 is involved in important biological pathways such as the tight junction pathway and the barrier permeability regulation pathway. Through these pathways it interacts with proteins like occludin and various signaling molecules. This involvement allows tight regulation of barrier permeability ensuring selective transport and preventing the passage of harmful substances into sensitive areas like the central nervous system.
- Associated diseases and disorders
Claudin 5 plays a significant role in conditions like cerebral edema and Alzheimer's disease. Altered expression or dysfunction of Claudin 5 disrupts the blood-brain barrier contributing to these disorders. In Alzheimer's disease there is evidence of impaired tight junctions where Claudin 5 interacts with other claudins and related proteins like amyloid-beta affecting barrier integrity. Understanding these connections helps in developing therapeutic strategies targeting tight junction stability.
Product promise
Tested
We have tested this species and application combination and it works. It is covered by our product promise.
Expected
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
Predicted
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
Not recommended
We do not recommend this combination. It is not covered by our product promise.
We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.
In the unlikely event of one of our products not working as expected, you are covered by our product promise.
Full details and terms and conditions can be found here:
Terms & Conditions.
11 product images
![Western blot - Anti-Claudin 5 antibody [EPR7583] (ab131259), expandable thumbnail](https://content.abcam.com/products/images/claudin-5-antibody-epr7583-ab131259--western-blot-img105262.jpg "Western blot - Anti-Claudin 5 antibody [EPR7583] (ab131259)")
Western blot - Anti-Claudin 5 antibody [EPR7583] (ab131259)
All lanes: Western blot - Anti-Claudin 5 antibody [EPR7583] (ab131259) at 1/1000 dilution
Lane 1: Human fetal brain lysate at 10 µg
Lane 2: Human lung squamous cell cancer lysate at 10 µg
Lane 3: Human small cell lung cancer lysate at 10 µg
SecondaryAll lanes: HRP labelled Goat anti Rabbit IgG at 1/2000 dilution
Predicted band size: 23 kDa
![Western blot - Anti-Claudin 5 antibody [EPR7583] (ab131259), expandable thumbnail](https://content.abcam.com/products/images/claudin-5-antibody-epr7583-ab131259--western-blot-img161195.jpg "Western blot - Anti-Claudin 5 antibody [EPR7583] (ab131259)")
Western blot - Anti-Claudin 5 antibody [EPR7583] (ab131259)
Blocking buffer: 5% NFDM/TBST
Dilution buffer: 5% NFDM/TBSTAll lanes: Western blot - Anti-Claudin 5 antibody [EPR7583] (ab131259) at 1/5000 dilution
All lanes: Human small cell lung cancer at 10 µg
SecondaryAll lanes: HRP goat anti-rabbit IgG (H+L) at 1/5000 dilution
Predicted band size: 23 kDa
Observed band size: 20 kDa
![Western blot - Anti-Claudin 5 antibody [EPR7583] (ab131259), expandable thumbnail](https://content.abcam.com/products/images/claudin-5-antibody-epr7583-ab131259--western-blot-img25232.jpg "Western blot - Anti-Claudin 5 antibody [EPR7583] (ab131259)")
Western blot - Anti-Claudin 5 antibody [EPR7583] (ab131259)
Blocking buffer: 5% NFDM/TBST
Dilution buffer: 5% NFDM/TBSTAll lanes: Western blot - Anti-Claudin 5 antibody [EPR7583] (ab131259) at 1/20000 dilution
All lanes: Human lung squamous cell cancer lysate at 10 µg
SecondaryAll lanes: HRP goat anti-rabbit IgG (H+L) at 1/5000 dilution
Predicted band size: 11 kDa, 118 kDa, 13 kDa, 23 kDa, 25 kDa, 27 kDa, 29 kDa, 33 kDa, 34 kDa, 35 kDa, 66 kDa, 69 kDa, 70 kDa
Observed band size: 11 kDa, 118 kDa, 18 kDa, 20 kDa, 25-32 kDa, 40 kDa, 70 kDa, 74 kDa
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Claudin 5 antibody [EPR7583] (ab131259), expandable thumbnail](https://content.abcam.com/products/images/claudin-5-antibody-epr7583-ab131259--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img127875.jpg "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Claudin 5 antibody [EPR7583] (ab131259)")
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Claudin 5 antibody [EPR7583] (ab131259)
Immunohistochemical staining of paraffin embedded human colon with purified ab131259 at a working dilution of 1/1000. The secondary antibody used is HRP goat anti-rabbit IgG H&L (Goat Anti-Rabbit IgG H&L (HRP) ab97051) at 1/500. The sample is counter-stained with hematoxylin. Antigen retrieval was perfomed using Tris-EDTA buffer, pH 9.0. PBS was used instead of the primary antibody as the negative control, and is shown in the inset.
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Claudin 5 antibody [EPR7583] (ab131259), expandable thumbnail](https://content.abcam.com/products/images/claudin-5-antibody-epr7583-ab131259--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img74301.jpg "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Claudin 5 antibody [EPR7583] (ab131259)")
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Claudin 5 antibody [EPR7583] (ab131259)
Immunohistochemical analysis of paraffin embedded Human kidney tissue labelling Claudin 5 with unpurified ab131259 antibody at 1/100 dilution.
Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Claudin 5 antibody [EPR7583] (ab131259), expandable thumbnail](https://content.abcam.com/products/images/claudin-5-antibody-epr7583-ab131259--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img98433.jpg "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Claudin 5 antibody [EPR7583] (ab131259)")
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Claudin 5 antibody [EPR7583] (ab131259)
Immunohistochemical analysis of paraffin embedded Human lung tissue labelling Claudin 5 with unpurified ab131259 antibody at 1/100 dilution.
Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Claudin 5 antibody [EPR7583] (ab131259), expandable thumbnail](https://content.abcam.com/products/images/claudin-5-antibody-epr7583-ab131259--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img63795.jpg "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Claudin 5 antibody [EPR7583] (ab131259)")
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Claudin 5 antibody [EPR7583] (ab131259)
Unpurified ab131259 showing positive staining in Normal tonsil tissue.
Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Claudin 5 antibody [EPR7583] (ab131259), expandable thumbnail](https://content.abcam.com/products/images/claudin-5-antibody-epr7583-ab131259--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img107723.jpg "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Claudin 5 antibody [EPR7583] (ab131259)")
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Claudin 5 antibody [EPR7583] (ab131259)
Unpurified ab131259 showing positive staining in Normal placenta tissue.
Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Claudin 5 antibody [EPR7583] (ab131259), expandable thumbnail](https://content.abcam.com/products/images/claudin-5-antibody-epr7583-ab131259--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img11046.jpg "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Claudin 5 antibody [EPR7583] (ab131259)")
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Claudin 5 antibody [EPR7583] (ab131259)
Unpurified ab131259 showing positive staining in Normal uterus tissue.
Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Claudin 5 antibody [EPR7583] (ab131259), expandable thumbnail](https://content.abcam.com/products/images/claudin-5-antibody-epr7583-ab131259--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img66933.jpg "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Claudin 5 antibody [EPR7583] (ab131259)")
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Claudin 5 antibody [EPR7583] (ab131259)
Unpurified ab131259 showing positive staining in Normal colon tissue.
Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
![Immunocytochemistry/ Immunofluorescence - Anti-Claudin 5 antibody [EPR7583] (ab131259), expandable thumbnail](https://content.abcam.com/products/images/claudin-5-antibody-epr7583-ab131259--immunocytochemistry-immunofluorescence-img408358.jpg "Immunocytochemistry/ Immunofluorescence - Anti-Claudin 5 antibody [EPR7583] (ab131259)")
Immunocytochemistry/ Immunofluorescence - Anti-Claudin 5 antibody [EPR7583] (ab131259)
ab131259 staining Claudin 5 in HUV-EC cells. The cells were fixed with 100% methanol (5 min), permeabilized with 0.1% PBS-Tween for 5 minutes and then blocked with 1% BSA/10% normal goat serum/0.3M glycine in 0.1%PBS-Tween for 1h. The cells were then incubated overnight at 4°C with ab131259 at 0.008µg/ml and Anti-alpha Tubulin antibody [DM1A] - Loading Control ab7291, Mouse monoclonal [DM1A] to alpha Tubulin - Loading Control. Cells were then incubated with Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) preadsorbed ab150081, Goat polyclonal Secondary Antibody to Rabbit IgG - H&L (Alexa Fluor® 488), pre-adsorbed at 1/1000 dilution (shown in green) and Goat Anti-Mouse IgG H&L (Alexa Fluor® 594) preadsorbed ab150120, Goat polyclonal Secondary Antibody to Mouse IgG - H&L (Alexa Fluor® 594), pre-adsorbed at 1/1000 dilution (shown in pseudocolour red). Nuclear DNA was labelled with DAPI (shown in blue). Image was acquired with a high-content analyser (Operetta CLS, Perkin Elmer) and a maximum intensity projection of confocal sections is shown.
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Claudin 5 antibody [EPR7583] (ab131259), expandable thumbnail](https://content.abcam.com/products/images/claudin-5-antibody-epr7583-ab131259--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img98433.jpg/_jcr_content/renditions/webp-475.webp "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Claudin 5 antibody [EPR7583] (ab131259)")
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Claudin 5 antibody [EPR7583] (ab131259), expandable thumbnail](https://content.abcam.com/products/images/claudin-5-antibody-epr7583-ab131259--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img63795.jpg/_jcr_content/renditions/webp-475.webp "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Claudin 5 antibody [EPR7583] (ab131259)")
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Claudin 5 antibody [EPR7583] (ab131259), expandable thumbnail](https://content.abcam.com/products/images/claudin-5-antibody-epr7583-ab131259--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img107723.jpg/_jcr_content/renditions/webp-475.webp "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Claudin 5 antibody [EPR7583] (ab131259)")
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Claudin 5 antibody [EPR7583] (ab131259), expandable thumbnail](https://content.abcam.com/products/images/claudin-5-antibody-epr7583-ab131259--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img11046.jpg/_jcr_content/renditions/webp-475.webp "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Claudin 5 antibody [EPR7583] (ab131259)")
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Claudin 5 antibody [EPR7583] (ab131259), expandable thumbnail](https://content.abcam.com/products/images/claudin-5-antibody-epr7583-ab131259--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img66933.jpg/_jcr_content/renditions/webp-475.webp "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Claudin 5 antibody [EPR7583] (ab131259)")
![Immunocytochemistry/ Immunofluorescence - Anti-Claudin 5 antibody [EPR7583] (ab131259), expandable thumbnail](https://content.abcam.com/products/images/claudin-5-antibody-epr7583-ab131259--immunocytochemistry-immunofluorescence-img408358.jpg/_jcr_content/renditions/webp-475.webp "Immunocytochemistry/ Immunofluorescence - Anti-Claudin 5 antibody [EPR7583] (ab131259)")
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