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AB211452

Anti-CLEC12B antibody

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(1 Publication)

Rabbit Polyclonal CLEC12B antibody. Suitable for IHC-P, WB and reacts with Human, Mouse samples. Cited in 1 publication. Immunogen corresponding to Synthetic Peptide within Human CLEC12B aa 200 to C-terminus conjugated to Keyhole Limpet Haemocyanin.

View Alternative Names

UNQ5782/PRO16089, CLEC12B, C-type lectin domain family 12 member B, Macrophage antigen H

3 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CLEC12B antibody (AB211452)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CLEC12B antibody (AB211452)

Immunohistochemical analysis of formalin fixed, paraffin embedded Human pancreas tissue labeling CLEC12B with ab211452 at 1/100 dilution.

Western blot - Anti-CLEC12B antibody (AB211452)
  • WB

Supplier Data

Western blot - Anti-CLEC12B antibody (AB211452)

All lanes:

Western blot - Anti-CLEC12B antibody (ab211452) at 1/1000 dilution

All lanes:

Mouse testis tissue lysate at 35 µg

Predicted band size: 32 kDa

false

Western blot - Anti-CLEC12B antibody (AB211452)
  • WB

Supplier Data

Western blot - Anti-CLEC12B antibody (AB211452)

All lanes:

Western blot - Anti-CLEC12B antibody (ab211452) at 1/1000 dilution

All lanes:

K562 cell lysate at 35 µg

Predicted band size: 32 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Mouse, Human

Applications

WB, IHC-P

applications

Immunogen

Synthetic Peptide within Human CLEC12B aa 200 to C-terminus conjugated to Keyhole Limpet Haemocyanin. The exact immunogen used to generate this antibody is proprietary information.

Q2HXU8

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/100", "IHCP-species-notes": "<p></p>", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000", "WB-species-notes": "<p></p>" }, "Mouse": { "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000", "WB-species-notes": "<p></p>" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7.4 Preservative: 0.09% Sodium azide Constituents: PBS
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Inhibitory receptor postulated to negatively regulate immune and non-immune functions (PubMed : 17562706, PubMed : 34310951). Upon phosphorylation, recruits SH2 domain-containing PTPN6 and PTPN11 phosphatases to its ITIM motif and antagonizes activation signals (PubMed : 17562706, PubMed : 34310951). Although it inhibits KLRK1/NKG2D-mediated signaling, it does not bind known ligands of KLRK1/NKG2D and therefore is not its inhibitory counterpart (PubMed : 17562706). May limit activation of myeloid cell subsets in response to infection or tissue inflammation (PubMed : 17562706). May protect target cells against natural killer cell-mediated lysis (PubMed : 17562706). May negatively regulate cell cycle and differentiation of melanocytes via inactivation of STAT3 (PubMed : 34310951).
See full target information CLEC12B
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

The Journal of biological chemistry 297:101190 PubMed34517008

2021

African swine fever virus protein MGF-505-7R promotes virulence and pathogenesis by inhibiting JAK1- and JAK2-mediated signaling.

Applications

Unspecified application

Species

Unspecified reactive species

Dan Li,Jing Zhang,Wenping Yang,Pan Li,Yi Ru,Weifang Kang,LuLu Li,Yong Ran,Haixue Zheng
View all publications
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Product promise

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