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AB203200

Anti-CLEC5A antibody

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(2 Publications)

Rabbit Polyclonal CLEC5A antibody. Suitable for IHC-P, Flow Cyt and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Synthetic Peptide within Mouse Clec5a aa 50-150 conjugated to Keyhole Limpet Haemocyanin.

View Alternative Names

CLECSF5, MDL1, CLEC5A, C-type lectin domain family 5 member A, C-type lectin superfamily member 5, Myeloid DAP12-associating lectin 1, MDL-1

2 Images
Flow Cytometry - Anti-CLEC5A antibody (AB203200)
  • Flow Cyt

Supplier Data

Flow Cytometry - Anti-CLEC5A antibody (AB203200)

Flow Cytometric analysis of U937 cells labeling CLEC5A using ab203200 at 1/50 dilution (green) followed by a FITC conjugated secondary, compared to control cells (blue).

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CLEC5A antibody (AB203200)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CLEC5A antibody (AB203200)

Immunohistochemical analysis of formalin-fixed paraffin-embedded Human colon carcinoma tissue labeling CLEC5A with ab203200 at 1/200 dilution, followed by conjugation to the secondary antibody and DAB staining.

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

Flow Cyt, IHC-P

applications

Immunogen

Synthetic Peptide within Mouse Clec5a aa 50-150 conjugated to Keyhole Limpet Haemocyanin. The exact immunogen used to generate this antibody is proprietary information.

Q9R007

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/100 - 1/500", "IHCP-species-notes": "<p>Use at 1/50 - 1/200 with fluorescent detection methods.</p> Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.", "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "1/20 - 1/100", "FlowCyt-species-notes": "<p><a href='/en-us/products/primary-antibodies/rabbit-igg-polyclonal-isotype-control-chip-grade-ab171870'>ab171870</a> - Rabbit polyclonal IgG, is suitable for use as an isotype control with this antibody.</p>" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein A
Storage buffer
pH: 7.4 Preservative: 0.02% Proclin 300 Constituents: 50% Glycerol (glycerin, glycerine), 48.98% TBS, 1X, 1% BSA
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Functions as a positive regulator of osteoclastogenesis (By similarity). Cell surface receptor that signals via TYROBP (PubMed : 10449773). Regulates inflammatory responses (By similarity).. (Microbial infection) Critical macrophage receptor for dengue virus serotypes 1-4 (PubMed : 18496526, PubMed : 21566123). The binding of dengue virus to CLEC5A triggers signaling through the phosphorylation of TYROBP (PubMed : 18496526). This interaction does not result in viral entry, but stimulates pro-inflammatory cytokine release (PubMed : 18496526).
See full target information CLEC5A
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Publications (2)

Recent publications for all applications. Explore the full list and refine your search

Frontiers in cell and developmental biology 9:746932 PubMed34712666

2021

Identification of an Immune-Related Prognostic Gene CLEC5A Based on Immune Microenvironment and Risk Modeling of Ovarian Cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Jiacheng Shen,Tingwei Liu,Jia Lv,Shaohua Xu

Proceedings of the National Academy of Sciences of the United States of America 118: PubMed34551979

2021

Functional succinate dehydrogenase deficiency is a common adverse feature of clear cell renal cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Ritesh K Aggarwal,Rebecca A Luchtel,Venkata Machha,Alexander Tischer,Yiyu Zou,Kith Pradhan,Nadia Ashai,Nandini Ramachandra,Joseph M Albanese,Jung-In Yang,Xiaoyang Wang,Srinivas Aluri,Shanisha Gordon,Ahmed Aboumohamed,Benjamin A Gartrell,Sassan Hafizi,James Pullman,Niraj Shenoy
View all publications
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Product promise

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