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AB129186

Anti-CLIC3 antibody [EPR8244(B)]

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(1 Publication)

Rabbit Recombinant Monoclonal CLIC3 antibody. Suitable for WB and reacts with Human, Mouse, Rat samples. Cited in 1 publication.

View Alternative Names

Chloride intracellular channel protein 3, Glutaredoxin-like oxidoreductase CLIC3, CLIC3

1 Images
Western blot - Anti-CLIC3 antibody [EPR8244(B)] (AB129186)
  • WB

Unknown

Western blot - Anti-CLIC3 antibody [EPR8244(B)] (AB129186)

All lanes:

Western blot - Anti-CLIC3 antibody [EPR8244(B)] (ab129186) at 1/1000 dilution

Lane 1:

JAR lysates at 10 µg

Lane 2:

Rat kidney lysates at 10 µg

Lane 3:

Mouse kidney lysates at 10 µg

Lane 4:

Human fetal kidney lysates at 10 µg

Secondary

All lanes:

HRP labelled goat anti-rabbit at 1/2000 dilution

Predicted band size: 27 kDa

false

Key facts

Host species

Rabbit

Clonality

Monoclonal

Clone number

EPR8244(B)

Isotype

IgG

Carrier free

No

Reacts with

Mouse, Rat, Human

Applications

WB

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

Reactivity data

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Product details

Patented technology
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein A
Storage buffer
pH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Target data

In the soluble state, catalyzes glutaredoxin-like thiol disulfide exchange reactions with reduced glutathione as electron donor (PubMed : 28198360, PubMed : 37759794). Reduced in a glutathione-dependent way and secreted into the extracellular matrix where it activates TGM2 and promotes blood vessel growth during tissue remodeling as occurs in tumorigenesis. Can reduce specific cysteines in TGM2 and regulate cofactor binding (PubMed : 28198360). Can insert into membranes and form outwardly rectifying chloride ion channels. May participate in cellular growth control.
See full target information CLIC3

Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Allergologia et immunopathologia 52:46-52 PubMed38970264

2024

Knockdown of GNL3 inhibits LUAD cell growth by regulating Wnt-β-catenin pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Guihong Dai,Yuejun Sun
View all publications

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

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