AB67936

Anti-CLK4 antibody

Name: Anti-CLK4 antibody (ab67936) | Abcam
Brand: Abcam Limited
SKU: AB67936

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(3 Publications)

Mouse Polyclonal CLK4 antibody. Carrier free. Suitable for WB and reacts with Human samples. Cited in 3 publications. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human CLK4.

View Alternative Names

Dual specificity protein kinase CLK4, CDC-like kinase 4, CLK4

1 Images

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Western blot - Anti-CLK4 antibody (AB67936)

All lanes:

Western blot - Anti-CLK4 antibody (ab67936) at 1/500 dilution

Lane 1:

CLK4 transfected 293T cell lysate at 25 µg

Lane 2:

non transfected 293T cell lysate at 25 µg

Secondary

All lanes:

Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

Predicted band size: 57 kDa

Observed band size: 62 kDa

false

Key facts

Host species

Mouse

Clonality

Polyclonal

Isotype

IgG

Carrier free

Yes

Reacts with

Human

Applications

applications

Immunogen

Recombinant Full Length Protein corresponding to Human CLK4.

Q9HAZ1

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/1000", "WB-species-notes": "<p></p>" } } }

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Protein G

Storage buffer

pH: 7.4 Constituents: PBS

Shipped at conditions

Blue Ice

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine-rich (SR) proteins of the spliceosomal complex and may be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing. Phosphorylates SRSF1 and SRSF3. Required for the regulation of alternative splicing of MAPT/TAU. Regulates the alternative splicing of tissue factor (F3) pre-mRNA in endothelial cells.

See full target information CLK4

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Publications (3)

Recent publications for all applications. Explore the full list and refine your search

Clinical and translational medicine 12:e719 PubMed35092699

2022

Methionine oxidation of CLK4 promotes the metabolic switch and redox homeostasis in esophageal carcinoma via inhibiting MITF selective autophagy.

Applications

Unspecified application

Species

Unspecified reactive species

Yaxing Shen,Heng Zhang,Shihua Yao,Feng Su,Hao Wang,Jun Yin,Yong Fang,Lijie Tan,Kaiguang Zhang,Xiangshan Fan,Ming Zhong,Qingxin Zhou,Jie He,Zhiyong Zhang

The Journal of experimental medicine 217: PubMed32453420

2020

Targeting CLK3 inhibits the progression of cholangiocarcinoma by reprogramming nucleotide metabolism.

Applications

Unspecified application

Species

Unspecified reactive species

Qingxin Zhou,Meihua Lin,Xing Feng,Fei Ma,Yuekun Zhu,Xing Liu,Chao Qu,Hong Sui,Bei Sun,Anlong Zhu,Heng Zhang,He Huang,Zhi Gao,Yongxiang Zhao,Jiangyun Sun,Yuxian Bai,Junfei Jin,Xuehui Hong,Chang Zou,Zhiyong Zhang

Molecules and cells 37:888-98 PubMed25518923

2014

Comparative proteomic profiling of pancreatic ductal adenocarcinoma cell lines.

Applications

Unspecified application

Species

Unspecified reactive species

Yikwon Kim,Dohyun Han,Hophil Min,Jonghwa Jin,Eugene C Yi,Youngsoo Kim

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-CLK4 antibody

Western blot - Anti-CLK4 antibody (AB67936)

Key facts

Host species

Clonality

Isotype

Carrier free

Reacts with

Applications

Immunogen

Complementary Products

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Reactivity data

Properties and storage information

Form

Purification technique

Storage buffer

Shipped at conditions

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Aliquoting information

Storage information

Product protocols

Target data

Publications (3)

Product promise