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AB13712

Anti-CLLD8/SETDB2 antibody

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(3 Publications)

Goat Polyclonal CLLD8/SETDB2 antibody. Suitable for WB and reacts with Human samples. Cited in 3 publications. Immunogen corresponding to Synthetic Peptide within Human SETDB2 aa 1-50.

View Alternative Names

C13orf4, CLLD8, KMT1F, SETDB2, Histone-lysine N-methyltransferase SETDB2, Chronic lymphocytic leukemia deletion region gene 8 protein, Lysine N-methyltransferase 1F, SET domain bifurcated 2

1 Images
Western blot - Anti-CLLD8/SETDB2 antibody (AB13712)
  • WB

Supplier Data

Western blot - Anti-CLLD8/SETDB2 antibody (AB13712)

Detected by chemiluminescence.

RIPA buffer.

All lanes:

Western blot - Anti-CLLD8/SETDB2 antibody (ab13712) at 0.3 µg/mL

All lanes:

HeLa (Human epithelial cell line from cervix adenocarcinoma) nuclear lysate at 35 µg

Predicted band size: 82 kDa

false

Key facts

Host species

Goat

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

WB

applications

Immunogen

Synthetic Peptide within Human SETDB2 aa 1-50. The exact immunogen used to generate this antibody is proprietary information.

Q96T68

Specificity

This antibody has been shown to detect SETDB2 in overexpression cell extracts.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "", "WB-species-notes": "<p>1 hour primary incubation is recommended for this product.</p>" }, "Mouse": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Rat": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Cow": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Dog": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Pig": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Purification notes
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Storage buffer
pH: 7.3 Preservative: 0.02% Sodium azide Constituents: 99% Tris buffered saline, 0.5% BSA
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Histone methyltransferase involved in left-right axis specification in early development and mitosis. Specifically trimethylates 'Lys-9' of histone H3 (H3K9me3). H3K9me3 is a specific tag for epigenetic transcriptional repression that recruits HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Contributes to H3K9me3 in both the interspersed repetitive elements and centromere-associated repeats. Plays a role in chromosome condensation and segregation during mitosis.
See full target information SETDB2
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Publications (3)

Recent publications for all applications. Explore the full list and refine your search

Oncology reports 45: PubMed33846793

2021

CREB stimulates GPX4 transcription to inhibit ferroptosis in lung adenocarcinoma.

Applications

Unspecified application

Species

Unspecified reactive species

Zhixian Wang,Xiao Zhang,Xiaoting Tian,Yueyue Yang,Lifang Ma,Jiayi Wang,Yongchun Yu

Cancer management and research 12:783-792 PubMed32099474

2020

Oncogenic Roles Of A Histone Methyltransferase SETDB2 In AML1-ETO Positive AML.

Applications

Unspecified application

Species

Unspecified reactive species

Guangfu Mu,Fangping Chen

Cancer cell 35:677-691.e10 PubMed30991027

2019

Small-Molecule Targeting of Oncogenic FTO Demethylase in Acute Myeloid Leukemia.

Applications

Unspecified application

Species

Unspecified reactive species

Yue Huang,Rui Su,Yue Sheng,Lei Dong,Ze Dong,Hongjiao Xu,Tengfeng Ni,Zijie Scott Zhang,Tao Zhang,Chenying Li,Li Han,Zhenyun Zhu,Fulin Lian,Jiangbo Wei,Qiangqiang Deng,Yungui Wang,Mark Wunderlich,Zhiwei Gao,Guoyu Pan,Dafang Zhong,Hu Zhou,Naixia Zhang,Jianhua Gan,Hualiang Jiang,James C Mulloy,Zhijian Qian,Jianjun Chen,Cai-Guang Yang
View all publications
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Product promise

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