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AB126102

Anti-CLPP antibody

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(3 Publications)

Rabbit Polyclonal CLPP antibody. Suitable for IHC-P, WB and reacts with Human samples. Cited in 3 publications. Immunogen corresponding to Recombinant Fragment Protein within Human CLPP aa 1-250.

View Alternative Names

Caseinolytic mitochondrial matrix peptidase proteolytic subunit, Endopeptidase Clp, CLPP

2 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CLPP antibody (AB126102)
  • IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CLPP antibody (AB126102)

ab126102, at 1/250 dilution, staining CLPP in paraffin-embedded Human colon carcinoma tissue by Immunohistochemistry.

Western blot - Anti-CLPP antibody (AB126102)
  • WB

Unknown

Western blot - Anti-CLPP antibody (AB126102)

12% SDS Page

All lanes:

Western blot - Anti-CLPP antibody (ab126102) at 1/1000 dilution

All lanes:

Jurkat whole cell lysate at 30 µg

Predicted band size: 30 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

WB, IHC-P

applications

Immunogen

Recombinant Fragment Protein within Human CLPP aa 1-250. The exact immunogen used to generate this antibody is proprietary information.

Q16740

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/100 - 1/1000", "IHCP-species-notes": "<p></p>", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/3000", "WB-species-notes": "<p></p>" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7 Preservative: 0.01% Thimerosal (merthiolate) Constituents: 20% Glycerol (glycerin, glycerine), 1.21% Tris, 0.75% Glycine
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Protease component of the ClpXP complex that cleaves peptides and various proteins in an ATP-dependent process. Has low peptidase activity in the absence of CLPX. The ClpXP complex can degrade CSN1S1, CSN2 and CSN3, as well as synthetic peptides (in vitro) and may be responsible for a fairly general and central housekeeping function rather than for the degradation of specific substrates (PubMed : 11923310, PubMed : 15522782). Cleaves PINK1 in the mitochondrion (PubMed : 22354088).
See full target information CLPP
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Publications (3)

Recent publications for all applications. Explore the full list and refine your search

Cell reports. Medicine 5:101840 PubMed39626672

2024

Chemical activation of mitochondrial ClpP to modulate energy metabolism of CD4 T cell for inflammatory bowel diseases treatment.

Applications

Unspecified application

Species

Unspecified reactive species

Jiangnan Zhang,Yunhan Jiang,Dongmei Fan,Zhiqiang Qiu,Xinlian He,Song Liu,Linjie Li,Zhengyi Dai,Lidan Zhang,Ziyi Shu,Lili Li,Hu Zhang,Tao Yang,Youfu Luo

Frontiers in pharmacology 13:859978 PubMed35652041

2022

Rosmarinic Acid Inhibits Mitochondrial Damage by Alleviating Unfolded Protein Response.

Applications

Unspecified application

Species

Unspecified reactive species

Guoen Cai,Fabin Lin,Dihang Wu,Chenxin Lin,Huiyun Chen,Yicong Wei,Huidan Weng,Zhiting Chen,Minxia Wu,En Huang,Zucheng Ye,Qinyong Ye

Journal of thoracic disease 14:507-514 PubMed35280491

2022

Downregulated RPL6 inhibits lung cancer cell proliferation and migration and promotes cell apoptosis by regulating the AKT signaling pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Jin Zhang,Qianli Ma,Yu Han,Huanshun Wen,Zhenrong Zhang,Yang Hao,Fei Xiao,Chaoyang Liang
View all publications
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Product promise

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