AB121846

Anti-COL22A1 antibody

Name: Anti-COL22A1 antibody (ab121846) | Abcam
Brand: Abcam Limited
SKU: AB121846
Rating: 5 (4 reviews)

(4 Reviews)

(9 Publications)

Rabbit Polyclonal COL22A1 antibody. Suitable for IHC-P, ICC and reacts with Human samples. Cited in 9 publications. Immunogen corresponding to Recombinant Fragment Protein within Human COL22A1 aa 150-300.

View Alternative Names

Collagen alpha-1(XXII) chain, COL22A1

5 Images

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Immunocytochemistry - Anti-COL22A1 antibody (AB121846)

Immunocytochemistry analysis of human cell line U-2 OS cells labelling COL22A1 with ab121846 at 2 μg/mL

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-COL22A1 antibody (AB121846)

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-COL22A1 antibody (AB121846)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human placenta tissue labelling COL22A1 with ab121846 at 1/200 dilution. Heat mediated antigen retrieval performed with citrate buffer pH 6 before commencing with IHC staining protocol.

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-COL22A1 antibody (AB121846)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human small intestine tissue labelling COL22A1 with ab121846 at 1/200 dilution. Heat mediated antigen retrieval performed with citrate buffer pH 6 before commencing with IHC staining protocol.

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-COL22A1 antibody (AB121846)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human stomach tissue labelling COL22A1 with ab121846 at 1/200 dilution. Heat mediated antigen retrieval performed with citrate buffer pH 6 before commencing with IHC staining protocol.

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-COL22A1 antibody (AB121846)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human liver tissue labelling COL22A1 with ab121846 at 1/200 dilution. Heat mediated antigen retrieval performed with citrate buffer pH 6 before commencing with IHC staining protocol.

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

Reacts with

Human

Applications

IHC-P, ICC

applications

Immunogen

Recombinant Fragment Protein within Human COL22A1 aa 150-300. The exact immunogen used to generate this antibody is proprietary information.

Q8NFW1

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "ICC" : {"fullname" : "Immunocytochemistry", "shortname":"ICC"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/200 - 1/500", "IHCP-species-notes": "<p></p> Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.", "ICC-species-checked": "testedAndGuaranteed", "ICC-species-dilution-info": "", "ICC-species-notes": "<p></p>" } } }

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Immunogen

Storage buffer

pH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine)

Shipped at conditions

Blue Ice

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Acts as a cell adhesion ligand for skin epithelial cells and fibroblasts.

See full target information COL22A1

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Publications (9)

Recent publications for all applications. Explore the full list and refine your search

International journal of genomics 2025:6587097 PubMed40438725

2025

COL22A1 Activates the PI3K/AKT Signaling Pathway to Sustain the Malignancy of Glioblastoma.

Applications

Unspecified application

Species

Unspecified reactive species

Tao Zheng,Yuanzhi Huang,Dong Chu,Shiming He

International journal of molecular sciences 24: PubMed36834940

2023

Inhibition of Ribosomal RNA Processing 15 Homolog (RRP15) Suppressed Tumor Growth, Invasion and Epithelial to Mesenchymal Transition (EMT) of Colon Cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Zirong Deng,Yun Xu,Yuchen Cai,Weiling Lin,Libei Zhang,Aoqing Jiang,Yuhang Zhou,Rui Zhao,Heyan Zhao,Zhaoguo Liu,Tingdong Yan

Proceedings of the National Academy of Sciences of the United States of America 120:e2206324120 PubMed36595689

2023

Dystrophin myonuclear domain restoration governs treatment efficacy in dystrophic muscle.

Applications

Unspecified application

Species

Unspecified reactive species

Adrien Morin,Amalia Stantzou,Olga N Petrova,John Hildyard,Thomas Tensorer,Meriem Matouk,Mina V Petkova,Isabelle Richard,Tudor Manoliu,Aurélie Goyenvalle,Sestina Falcone,Markus Schuelke,Corinne Laplace-Builhé,Richard J Piercy,Luis Garcia,Helge Amthor

Communications biology 5:1233 PubMed36371589

2022

Single-cell transcriptome analysis reveals cellular heterogeneity in mouse intra- and extra articular ligaments.

Applications

Unspecified application

Species

Unspecified reactive species

Kyota Ishibashi,Kentaro Ikegami,Takashi Shimbo,Eiji Sasaki,Tomomi Kitayama,Yuzuru Nakamura,Takahiro Tsushima,Yasuyuki Ishibashi,Katsuto Tamai

Journal of cellular and molecular medicine 26:5473-5485 PubMed36196630

2022

Engrailed homeobox 1 transcriptional regulation of COL22A1 inhibits nasopharyngeal carcinoma cell senescence through the G1/S phase arrest.

Applications

Unspecified application

Species

Unspecified reactive species

Mao-Ling Huang,Wen-Long Luo

Frontiers in immunology 13:1017120 PubMed36189307

2022

A novel immune cell signature for predicting osteosarcoma prognosis and guiding therapy.

Applications

Unspecified application

Species

Unspecified reactive species

Runsang Pan,Feng Pan,Zhirui Zeng,Shan Lei,Yan Yang,Yushi Yang,Chujiao Hu,Houping Chen,Xiaobin Tian

Nature communications 13:4989 PubMed36008423

2022

Cellular taxonomy of Hic1 mesenchymal progenitor derivatives in the limb: from embryo to adult.

Applications

Unspecified application

Species

Unspecified reactive species

Martin Arostegui,R Wilder Scott,Kerstin Böse,T Michael Underhill

Nature communications 13:2447 PubMed35508470

2022

Dual functions of microRNA-17 in maintaining cartilage homeostasis and protection against osteoarthritis.

Applications

Unspecified application

Species

Unspecified reactive species

Yun Zhang,Shuaijun Li,Peisheng Jin,Ting Shang,Ruizhu Sun,Laiya Lu,Kaijin Guo,Jiping Liu,Yongjuan Tong,Junbang Wang,Sanhong Liu,Chen Wang,Yubin Kang,Wenmin Zhu,Qian Wang,Xiaoren Zhang,Feng Yin,Yi Eve Sun,Lei Cui

Cell stem cell 25:797-813.e9 PubMed31809738

2019

Hic1 Defines Quiescent Mesenchymal Progenitor Subpopulations with Distinct Functions and Fates in Skeletal Muscle Regeneration.

Applications

Unspecified application

Species

Unspecified reactive species

R Wilder Scott,Martin Arostegui,Ronen Schweitzer,Fabio M V Rossi,T Michael Underhill

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-COL22A1 antibody

Immunocytochemistry - Anti-COL22A1 antibody (AB121846)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-COL22A1 antibody (AB121846)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-COL22A1 antibody (AB121846)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-COL22A1 antibody (AB121846)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-COL22A1 antibody (AB121846)

Key facts

Host species

Clonality

Isotype

Carrier free

Reacts with

Applications

Immunogen

Reactivity data

Properties and storage information

Form

Purification technique

Storage buffer

Shipped at conditions

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Aliquoting information

Storage information

Product protocols

Target data

Publications (9)

Complementary Products

Secondary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Product promise