Rabbit Polyclonal COL1A1 antibody. Suitable for WB and reacts with Recombinant fragment - Human, Human, Pig samples. Cited in 9 publications. Immunogen corresponding to Recombinant Fragment Protein within Human COL1A1 aa 1200-1450.
View Alternative Names
Collagen alpha-1(I) chain, Alpha-1 type I collagen, COL1A1
- WB
Supplier Data
Western blot - Anti-Collagen I antibody (AB233080)
All lanes:
Western blot - Anti-Collagen I antibody (ab233080) at 2 µg/mL
All lanes:
Recombinant human Collagen I protein
Secondary
All lanes:
HRP-Linked Guinea pig Anti-Rabbit at 1/2000 dilution
Predicted band size: 139 kDa
false
- WB
Supplier Data
Western blot - Anti-Collagen I antibody (AB233080)
All lanes:
Western blot - Anti-Collagen I antibody (ab233080) at 2 µg/mL
Lane 1:
Human placenta lysate
Lane 2:
Human liver lysate
Lane 3:
Pig skin lysate
Secondary
All lanes:
HRP-Linked Guinea pig Anti-Rabbit at 1/2000 dilution
Predicted band size: 139 kDa
false
Reactivity data
Properties and storage information
Form
Purification technique
Purification notes
Storage buffer
Shipped at conditions
Appropriate short-term storage duration
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Aliquoting information
Storage information
Supplementary information
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
Collagen type I plays a central role in maintaining the extracellular matrix and supporting cellular environments. It interacts with other matrix proteins and cells forming complexes that help in tissue development and repair. Type I collagen is especially important in bone matrix working alongside minerals like hydroxyapatite to provide rigidity and support. Anti-collagen antibodies aid in studying its biological functions and interactions which are critical to understanding tissue dynamics.
Pathways
Collagen type I interacts with multiple signaling cascades involved in tissue remodeling and repair. It is a significant player in the TGF-β pathway which regulates fibrosis and wound healing processes. In these pathways proteins such as fibronectin and integrins work in concert with collagen type I to orchestrate cellular responses to damage. Researchers often examine its role in these pathways to uncover therapeutic possibilities for disease interventions.
Product protocols
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Target data
Publications (9)
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iScience 26:107618 PubMed37664614
2023
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Advanced healthcare materials 12:e2301180 PubMed37463568
2023
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Bio-medical materials and engineering 34:289-304 PubMed36617774
2023
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Pharmaceuticals (Basel, Switzerland) 15: PubMed36422523
2022
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BMC complementary medicine and therapies 22:63 PubMed35272637
2022
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Materials today. Bio 14:100234 PubMed35308043
2022
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Cell death & disease 12:474 PubMed33980818
2021
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American journal of translational research 12:6464-6477 PubMed33194044
2020
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Frontiers in cardiovascular medicine 6:170 PubMed31921893
2019
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Product promise
Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.
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