Rabbit Polyclonal COL1A1 antibody. Suitable for WB and reacts with Recombinant fragment - Human, Human, Pig samples. Cited in 18 publications. Immunogen corresponding to Recombinant Fragment Protein within Human COL1A1 aa 1200-1450.
View Alternative Names
Collagen alpha-1(I) chain, Alpha-1 type I collagen, COL1A1
- WB
Supplier Data
Western blot - Anti-Collagen I antibody (AB233080)
All lanes:
Western blot - Anti-Collagen I antibody (ab233080) at 2 µg/mL
All lanes:
Recombinant human Collagen I protein
Secondary
All lanes:
HRP-Linked Guinea pig Anti-Rabbit at 1/2000 dilution
Predicted band size: 139 kDa
false
- WB
Supplier Data
Western blot - Anti-Collagen I antibody (AB233080)
All lanes:
Western blot - Anti-Collagen I antibody (ab233080) at 2 µg/mL
Lane 1:
Human placenta lysate
Lane 2:
Human liver lysate
Lane 3:
Pig skin lysate
Secondary
All lanes:
HRP-Linked Guinea pig Anti-Rabbit at 1/2000 dilution
Predicted band size: 139 kDa
false
Reactivity data
Properties and storage information
Form
Purification technique
Purification notes
Storage buffer
Shipped at conditions
Appropriate short-term storage duration
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Aliquoting information
Storage information
Supplementary information
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
Collagen type I plays a central role in maintaining the extracellular matrix and supporting cellular environments. It interacts with other matrix proteins and cells forming complexes that help in tissue development and repair. Type I collagen is especially important in bone matrix working alongside minerals like hydroxyapatite to provide rigidity and support. Anti-collagen antibodies aid in studying its biological functions and interactions which are critical to understanding tissue dynamics.
Pathways
Collagen type I interacts with multiple signaling cascades involved in tissue remodeling and repair. It is a significant player in the TGF-β pathway which regulates fibrosis and wound healing processes. In these pathways proteins such as fibronectin and integrins work in concert with collagen type I to orchestrate cellular responses to damage. Researchers often examine its role in these pathways to uncover therapeutic possibilities for disease interventions.
Product protocols
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Target data
Publications (18)
Recent publications for all applications. Explore the full list and refine your search
Tissue engineering and regenerative medicine 22:57-75 PubMed39579168
2024
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Lasers in surgery and medicine 56:298-304 PubMed38304960
2024
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The Journal of biological chemistry 300:105502 PubMed38016515
2023
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Stem cells translational medicine 12:838-848 PubMed37804518
2023
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iScience 26:107618 PubMed37664614
2023
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Advanced healthcare materials 12:e2301180 PubMed37463568
2023
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Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft 250:152141 PubMed37499701
2023
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Bioengineering (Basel, Switzerland) 10: PubMed36978682
2023
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Biomedicines 11: PubMed36979856
2023
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Bio-medical materials and engineering 34:289-304 PubMed36617774
2023
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Product promise
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