AB111742

Anti-Collagen Type IV alpha 3 (COL4a3) antibody

Name: Anti-Collagen Type IV alpha 3 (COL4a3) antibody (ab111742) | Abcam
Brand: Abcam Limited
SKU: AB111742
Price: 525 USD
Availability: InStock

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(7 Publications)

Rabbit Polyclonal Collagen Type IV alpha 3 (COL4a3) antibody. Suitable for IHC-P, ICC/IF and reacts with Human, African green monkey samples. Cited in 5 publications. Immunogen corresponding to Synthetic Peptide within Human Collagen alpha-3(IV) chain.

View Alternative Names

Collagen alpha-3(IV) chain, Goodpasture antigen, COL4A3

2 Images

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Collagen Type IV alpha 3 (COL4a3) antibody (AB111742)

IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Collagen Type IV alpha 3 (COL4a3) antibody (AB111742)

ab111742 at 1/50 dilution staining COL4A3 in paraffin-embedded Human Brain tissue by Immunohistochemistry. The image on the right is treated with the synthesized peptide.

Immunocytochemistry/ Immunofluorescence - Anti-Collagen Type IV alpha 3 (COL4a3) antibody (AB111742)

ICC/IF

Unknown

Immunocytochemistry/ Immunofluorescence - Anti-Collagen Type IV alpha 3 (COL4a3) antibody (AB111742)

ab111742 at 1/100 dilution staining COL4A3 in COS7 cells by Immunofluorescence. The image on the right is treated with the synthesized peptide.

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

Reacts with

Human, African green monkey

Applications

ICC/IF, IHC-P

applications

Immunogen

Synthetic Peptide within Human Collagen alpha-3(IV) chain. The exact immunogen used to generate this antibody is proprietary information.

Q01955

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/50 - 1/100", "IHCP-species-notes": "<p></p> Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "African green monkey": { "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "1/100 - 1/500", "ICCIF-species-notes": "<p></p>" } } }

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Immunogen

Storage buffer

pH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine), 0.88% Sodium chloride

Shipped at conditions

Blue Ice

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Storage information

Stable for 12 months at -20°C

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.. Tumstatin, a cleavage fragment corresponding to the collagen alpha 3(IV) NC1 domain, possesses both anti-angiogenic and anti-tumor cell activity; these two anti-tumor properties may be regulated via RGD-independent ITGB3-mediated mechanisms.

See full target information Collagen alpha-3(IV) chain

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Publications (7)

Recent publications for all applications. Explore the full list and refine your search

Frontiers in pharmacology 16:1509196 PubMed40183102

2025

The role of atropine in myopia control: insights into choroidal and scleral mechanisms.

Applications

Unspecified application

Species

Unspecified reactive species

Longxiang Huang,Jingjin Zhang,Youfang Luo

Kidney international reports 8:1864-1874 PubMed37705901

2023

COL4A3 Mutation Induced Podocyte Apoptosis by Dysregulation of NADPH Oxidase 4 and MMP-2.

Applications

Unspecified application

Species

Unspecified reactive species

Jun Tong,Qimin Zheng,Xiangchen Gu,Qinjie Weng,Shuwen Yu,Zhengying Fang,Hafiz Muhammad Jafar Hussain,Jing Xu,Hong Ren,Nan Chen,Jingyuan Xie

African health sciences 22:334-342 PubMed36407358

2022

The effects of Juglone-Selenium combination on invasion and metastasis in pancreatic cancer cell lines.

Applications

Unspecified application

Species

Unspecified reactive species

Hilal Arikoglu,Duygu Dursunoglu,Dudu Erkoc Kaya,Ebru Avci

Frontiers in pharmacology 13:990401 PubMed36204234

2022

AZD6738 Inhibits fibrotic response of conjunctival fibroblasts by regulating checkpoint kinase 1/ and / pathways.

Applications

Unspecified application

Species

Unspecified reactive species

Longxiang Huang,Qin Ye,Chunlin Lan,Xiaohui Wang,Yihua Zhu

Cell death & disease 13:522 PubMed35661704

2022

Decoy receptor 2 mediates the apoptosis-resistant phenotype of senescent renal tubular cells and accelerates renal fibrosis in diabetic nephropathy.

Applications

Unspecified application

Species

Unspecified reactive species

Jia Chen,Ke-Hong Chen,Li-Ming Wang,Jia Luo,Quan-You Zheng,Ya-Ni He

Frontiers in genetics 10:628 PubMed31312213

2019

A Nonsense Mutation in COL4A4 Gene Causing Isolated Hematuria in Either Heterozygous or Homozygous State.

Applications

Unspecified application

Species

Unspecified reactive species

Cheng Yang,Yuan Song,Zhaowei Chen,Xiaohan Yuan,Xinhua Chen,Guohua Ding,Yang Guan,Mary McGrath,Chunhua Song,Yongqing Tong,Huiming Wang

Clinical journal of the American Society of Nephrology : CJASN 13:1162-1171 PubMed30012629

2018

Gene Variants and Diabetic Kidney Disease in MODY.

Applications

Unspecified application

Species

Unspecified reactive species

Yiting Wang,Junlin Zhang,Yingwang Zhao,Shanshan Wang,Jie Zhang,Qianqian Han,Rui Zhang,Ruikun Guo,Hanyu Li,Li Li,Tingli Wang,Xi Tang,Changzheng He,Geer Teng,Weiyue Gu,Fang Liu

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-Collagen Type IV alpha 3 (COL4a3) antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Collagen Type IV alpha 3 (COL4a3) antibody (AB111742)

Immunocytochemistry/ Immunofluorescence - Anti-Collagen Type IV alpha 3 (COL4a3) antibody (AB111742)

Key facts

Host species

Clonality

Isotype

Carrier free

Reacts with

Applications

Immunogen

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Reactivity data

Properties and storage information

Form

Purification technique

Storage buffer

Shipped at conditions

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Storage information

Product protocols

Target data

Publications (7)

Product promise